| Optogenetic and potassium channel gene therapy in a rodent model of focal neocortical epilepsy RC Wykes, JH Heeroma, L Mantoan, K Zheng, DC MacDonald, ... Science translational medicine 4 (161), 161ra152-161ra152, 2012 | 314 | 2012 |
| Functional evidence for the expression of P2X1, P2X4 and P2X7 receptors in human lung mast cells K Wareham, C Vial, RCE Wykes, P Bradding, EP Seward British journal of pharmacology 157 (7), 1215-1224, 2009 | 115 | 2009 |
| Epilepsy gene therapy using an engineered potassium channel A Snowball, E Chabrol, RC Wykes, T Shekh-Ahmad, JH Cornford, A Lieb, ... Journal of neuroscience 39 (16), 3159-3169, 2019 | 107 | 2019 |
| Functional transient receptor potential melastatin 7 channels are critical for human mast cell survival RCE Wykes, M Lee, SM Duffy, W Yang, EP Seward, P Bradding The Journal of Immunology 179 (6), 4045-4052, 2007 | 102 | 2007 |
| Gene therapy in epilepsy—is it time for clinical trials? DM Kullmann, S Schorge, MC Walker, RC Wykes Nature Reviews Neurology 10 (5), 300-304, 2014 | 95 | 2014 |
| Focal cortical seizures start as standing waves and propagate respecting homotopic connectivity LF Rossi, RC Wykes, DM Kullmann, M Carandini Nature communications 8 (1), 217, 2017 | 87 | 2017 |
| Full-bandwidth electrophysiology of seizures and epileptiform activity enabled by flexible graphene microtransistor depth neural probes A Bonaccini Calia, E Masvidal-Codina, TM Smith, N Schäfer, D Rathore, ... Nature Nanotechnology 17 (3), 301-309, 2022 | 78 | 2022 |
| Optogenetic approaches to treat epilepsy RC Wykes, DM Kullmann, I Pavlov, V Magloire Journal of neuroscience methods 260, 215-220, 2016 | 70 | 2016 |
| Gene therapy and editing: Novel potential treatments for neuronal channelopathies RC Wykes, G Lignani Neuropharmacology 132, 108-117, 2018 | 56 | 2018 |
| Seizures and disturbed brain potassium dynamics in the leukodystrophy megalencephalic leukoencephalopathy with subcortical cysts M Dubey, E Brouwers, EMC Hamilton, O Stiedl, M Bugiani, H Koch, ... Annals of Neurology 83 (3), 636-649, 2018 | 44 | 2018 |
| Changes in the physiology of CA1 hippocampal pyramidal neurons in preplaque CRND8 mice R Wykes, A Kalmbach, M Eliava, J Waters Neurobiology of aging 33 (8), 1609-1623, 2012 | 36 | 2012 |
| Differential regulation of endogenous N-and P/Q-type Ca2+ channel inactivation by Ca2+/calmodulin impacts on their ability to support exocytosis in chromaffin cells RCE Wykes, CS Bauer, SU Khan, JL Weiss, EP Seward Journal of Neuroscience 27 (19), 5236-5248, 2007 | 33 | 2007 |
| Gene therapy in status epilepticus MC Walker, S Schorge, DM Kullmann, RC Wykes, JH Heeroma, ... Epilepsia 54, 43-45, 2013 | 27 | 2013 |
| Genetic dissection of down syndrome-associated alterations in APP/amyloid-β biology using mouse models JL Tosh, ER Rhymes, P Mumford, HT Whittaker, LJ Pulford, SJ Noy, ... Scientific Reports 11 (1), 5736, 2021 | 22 | 2021 |
| Converging mechanisms of epileptogenesis and their insight in glioblastoma KE Hills, K Kostarelos, RC Wykes Frontiers in molecular neuroscience 15, 903115, 2022 | 21 | 2022 |
| WONOEP appraisal: Network concept from an imaging perspective RC Wykes, HM Khoo, L Caciagli, H Blumenfeld, P Golshani, J Kapur, ... Epilepsia 60 (7), 1293-1305, 2019 | 19 | 2019 |
| Characterization of optogenetically-induced cortical spreading depression in awake mice using graphene micro-transistor arrays E Masvidal-Codina, TM Smith, D Rathore, Y Gao, X Illa, E Prats-Alfonso, ... Journal of Neural Engineering 18 (5), 055002, 2021 | 18 | 2021 |
| Adiabatic dynamic causal modelling A Jafarian, P Zeidman, RC Wykes, M Walker, KJ Friston NeuroImage 238, 118243, 2021 | 17 | 2021 |
| The enlightened brain: novel imaging methods focus on epileptic networks at multiple scales LF Rossi, DM Kullmann, RC Wykes Frontiers in cellular neuroscience 12, 82, 2018 | 17 | 2018 |
| Semiology, clustering, periodicity and natural history of seizures in an experimental occipital cortical epilepsy model BL Chang, M Leite, A Snowball, A Lieb, E Chabrol, MC Walker, ... Disease Models & Mechanisms 11 (12), dmm036194, 2018 | 15 | 2018 |