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Laura D Healy
Laura D Healy
Postdoctoral Researcher, The Scripps Research Institute, Oregon Health & Science University
Dirección de correo verificada de scripps.edu
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Activated protein C inhibits neutrophil extracellular trap formation in vitro and activation in vivo
LD Healy, C Puy, JA Fernández, A Mitrugno, RS Keshari, NA Taku, ...
Journal of Biological Chemistry 292 (21), 8616-8629, 2017
1222017
Vitamin K–dependent protein S: beyond the protein C pathway
B Dahlbäck
Seminars in thrombosis and hemostasis 44 (02), 176-184, 2018
942018
The BCR-ABL inhibitor ponatinib inhibits platelet immunoreceptor tyrosine-based activation motif (ITAM) signaling, platelet activation and aggregate formation under shear
CP Loren, JE Aslan, RA Rigg, MS Nowak, LD Healy, A Gruber, BJ Druker, ...
Thrombosis research 135 (1), 155-160, 2015
882015
Oral administration of Bruton's tyrosine kinase inhibitors impairs GPVI-mediated platelet function
RA Rigg, JE Aslan, LD Healy, M Wallisch, MLD Thierheimer, CP Loren, ...
American Journal of Physiology-Cell Physiology 310 (5), C373-C380, 2016
832016
Histone deacetylase 6-mediated deacetylation of α-tubulin coordinates cytoskeletal and signaling events during platelet activation
JE Aslan, KG Phillips, LD Healy, A Itakura, J Pang, OJT McCarty
American Journal of Physiology-Cell Physiology 305 (12), C1230-C1239, 2013
492013
Heat shock protein 70 regulates platelet integrin activation, granule secretion and aggregation
RA Rigg, LD Healy, MS Nowak, J Mallet, MLD Thierheimer, J Pang, ...
American Journal of Physiology-Cell Physiology 310 (7), C568-C575, 2016
372016
Protease-activated receptor 4 activity promotes platelet granule release and platelet-leukocyte interactions
RA Rigg, LD Healy, TT Chu, ATP Ngo, A Mitrugno, J Zilberman-Rudenko, ...
Platelets 30 (1), 126-135, 2019
362019
Colocalization of neutrophils, extracellular DNA and coagulation factors during NETosis: development and utility of an immunofluorescence-based microscopy platform
LD Healy, C Puy, A Itakura, T Chu, DK Robinson, A Bylund, KG Phillips, ...
Journal of immunological methods 435, 77-84, 2016
362016
Measurement science in the circulatory system
CM Jones, SM Baker-Groberg, FA Cianchetti, JJ Glynn, LD Healy, ...
Cellular and molecular bioengineering 7, 1-14, 2014
332014
Hepatic thrombopoietin gene silencing reduces platelet count and breast cancer progression in transgenic MMTV-PyMT mice
T Shirai, AS Revenko, J Tibbitts, ATP Ngo, A Mitrugno, LD Healy, ...
Blood Advances 3 (20), 3080-3091, 2019
302019
Thrombin mutant W215A/E217A treatment improves neurological outcome and attenuates central nervous system damage in experimental autoimmune encephalomyelitis
NG Verbout, X Yu, LD Healy, KG Phillips, EI Tucker, A Gruber, ...
Metabolic brain disease 30, 57-65, 2015
262015
Regulation of immune cell signaling by activated protein C
LD Healy, RA Rigg, JH Griffin, OJT McCarty
Journal of leukocyte biology 103 (6), 1197-1203, 2018
212018
Activated protein C and PAR1‐derived and PAR3‐derived peptides are anti‐inflammatory by suppressing macrophage NLRP3 inflammasomes
LD Healy, JA Fernández, LO Mosnier, JH Griffin
Journal of Thrombosis and Haemostasis 19 (1), 269-280, 2021
162021
Pharmacological targeting of coagulation factor XI attenuates experimental autoimmune encephalomyelitis in mice
TCL Kohs, ME Fallon, EC Oseas, LD Healy, EI Tucker, D Gailani, ...
Metabolic brain disease 38 (7), 2383-2391, 2023
82023
Antithrombotic strategies after bioprosthetic aortic valve replacement: a systematic review
JN Papak, JC Chiovaro, N Noelck, LD Healy, M Freeman, JA Quin, ...
The Annals of thoracic surgery 107 (5), 1571-1581, 2019
72019
Contact system sends defensins to the rescue
LD Healy, OJT McCarty
Blood, The Journal of the American Society of Hematology 133 (5), 385-386, 2019
32019
Comparing antithrombotic strategies after bioprosthetic aortic valve replacement: a systematic review
J Papak, J Chiovaro, N Noelck, L Healy, M Freeman, R Paynter, A Low, ...
22018
An orthosteric/allosteric bivalent peptide agonist comprising covalently linked protease-activated receptor-derived peptides mimics in vitro and in vivo activities of activated …
LD Healy, JA Fernández, R Aiolfi, LO Mosnier, JH Griffin
Journal of Thrombosis and Haemostasis, 2024
12024
OC 49.2 Pharmacological Targeting of the Contact Pathway Attenuates Experimental Autoimmune Encephalomyelitis in Mice
T Kohs, M Fallon, E Oseas, L Healy, C Lorentz, E Tucker, O McCarty, ...
Research and Practice in Thrombosis and Haemostasis 7, 2023
12023
Heat shock protein 70 (Hsp70) regulates platelet integrin activation, granule secretion and aggregation
RA Rigg, LD Healy, MS Nowak, J Mallet, MLD Thierheimer, J Pang, ...
JOURNAL OF THROMBOSIS AND HAEMOSTASIS 14, 109-109, 2016
12016
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Artículos 1–20