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David R Spring
David R Spring
Dirección de correo verificada de ch.cam.ac.uk - Página principal
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Fluorescent chemosensors for Zn2+
Z Xu, J Yoon, DR Spring
Chemical Society Reviews 39 (6), 1996-2006, 2010
10802010
Diversity-oriented synthesis as a tool for the discovery of novel biologically active small molecules
WRJD Galloway, A Isidro-Llobet, DR Spring
Nature communications 1 (1), 80, 2010
8862010
Quorum sensing in Gram-negative bacteria: small-molecule modulation of AHL and AI-2 quorum sensing pathways
WRJD Galloway, JT Hodgkinson, SD Bowden, M Welch, DR Spring
Chemical reviews 111 (1), 28-67, 2011
7792011
Zn2+-Triggered Amide Tautomerization Produces a Highly Zn2+-Selective, Cell-Permeable, and Ratiometric Fluorescent Sensor
Z Xu, KH Baek, HN Kim, J Cui, X Qian, DR Spring, I Shin, J Yoon
Journal of the American Chemical Society 132 (2), 601-610, 2010
7302010
Arene C–H functionalisation using a removable/modifiable or a traceless directing group strategy
F Zhang, DR Spring
Chemical Society Reviews 43 (20), 6906-6919, 2014
6342014
Peptide stapling techniques based on different macrocyclisation chemistries
YH Lau, P De Andrade, Y Wu, DR Spring
Chemical Society Reviews 44 (1), 91-102, 2015
5752015
Cleavable linkers in antibody–drug conjugates
JD Bargh, A Isidro-Llobet, JS Parker, DR Spring
Chemical Society Reviews 48 (16), 4361-4374, 2019
5172019
Diversity-oriented synthesis: producing chemical tools for dissecting biology
CJ O'Connor, HSG Beckmann, DR Spring
Chemical Society Reviews 41 (12), 4444-4456, 2012
4592012
Combating multidrug‐resistant bacteria: current strategies for the discovery of novel antibacterials
KMG O'Connell, JT Hodgkinson, HF Sore, M Welch, GPC Salmond, ...
Angewandte Chemie International Edition 52 (41), 10706-10733, 2013
4542013
The molecular basis of the host response to lipopolysaccharide
CE Bryant, DR Spring, M Gangloff, NJ Gay
Nature Reviews Microbiology 8 (1), 8-14, 2010
4462010
Diversity-oriented synthesis; a challenge for synthetic chemists
DR Spring
Organic & biomolecular chemistry 1 (22), 3867-3870, 2003
4342003
Palladium-catalysed cross-coupling of organosilicon reagents
HF Sore, WRJD Galloway, DR Spring
Chemical Society Reviews 41 (5), 1845-1866, 2012
4132012
Chemical genetics to chemical genomics: small molecules offer big insights
DR Spring
Chemical Society Reviews 34 (6), 472-482, 2005
3922005
Diversity-oriented synthesis; a spectrum of approaches and results
RJ Spandl, A Bender, DR Spring
Organic & biomolecular chemistry 6 (7), 1149-1158, 2008
3722008
Finding new components of the target of rapamycin (TOR) signaling network through chemical genetics and proteome chips
J Huang, H Zhu, SJ Haggarty, DR Spring, H Hwang, F Jin, M Snyder, ...
Proceedings of the National Academy of Sciences 101 (47), 16594-16599, 2004
3162004
A lysosome-targetable fluorescent probe for imaging hydrogen sulfide in living cells
T Liu, Z Xu, DR Spring, J Cui
Organic letters 15 (9), 2310-2313, 2013
3142013
The multifaceted nature of antimicrobial peptides: Current synthetic chemistry approaches and future directions
BH Gan, J Gaynord, SM Rowe, T Deingruber, DR Spring
Chemical Society Reviews 50 (13), 7820-7880, 2021
3112021
Site-selective modification strategies in antibody–drug conjugates
SJ Walsh, JD Bargh, FM Dannheim, AR Hanby, H Seki, AJ Counsell, X Ou, ...
Chemical Society Reviews 50 (2), 1305-1353, 2021
3102021
Peptides as a platform for targeted therapeutics for cancer: Peptide–drug conjugates (PDCs)
BM Cooper, J Iegre, DH O'Donovan, MÖ Halvarsson, DR Spring
Chemical society reviews 50 (3), 1480-1494, 2021
2782021
Applications of small molecule activators and inhibitors of quorum sensing in Gram-negative bacteria
WRJD Galloway, JT Hodgkinson, S Bowden, M Welch, DR Spring
Trends in microbiology 20 (9), 449-458, 2012
2502012
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