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M. Dominik Fischer
M. Dominik Fischer
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Initial results from a first-in-human gene therapy trial on X-linked retinitis pigmentosa caused by mutations in RPGR
J Cehajic-Kapetanovic, K Xue, C Martinez-Fernandez de la Camara, ...
Nature medicine 26 (3), 354-359, 2020
2882020
Noninvasive, In Vivo Assessment of Mouse Retinal Structure Using Optical Coherence Tomography
MD Fischer, G Huber, SC Beck, N Tanimoto, R Muehlfriedel, E Fahl, ...
PloS one 4 (10), e7507, 2009
2492009
Restoration of cone vision in the CNGA3−/− mouse model of congenital complete lack of cone photoreceptor function
S Michalakis, R Mühlfriedel, N Tanimoto, V Krishnamoorthy, S Koch, ...
Molecular therapy 18 (12), 2057-2063, 2010
2322010
Spectral domain optical coherence tomography in mouse models of retinal degeneration
G Huber, SC Beck, C Grimm, A Sahaboglu-Tekgoz, F Paquet-Durand, ...
Investigative ophthalmology & visual science 50 (12), 5888-5895, 2009
2132009
Heregulin ameliorates the dystrophic phenotype in mdx mice
TOB Krag, S Bogdanovich, CJ Jensen, MD Fischer, J Hansen-Schwartz, ...
Proceedings of the National Academy of Sciences 101 (38), 13856-13860, 2004
2092004
Immune responses to retinal gene therapy using adeno-associated viral vectors–Implications for treatment success and safety
K Bucher, E Rodríguez-Bocanegra, D Dauletbekov, MD Fischer
Progress in retinal and eye research 83, 100915, 2021
1582021
Safety and vision outcomes of subretinal gene therapy targeting cone photoreceptors in achromatopsia: a nonrandomized controlled trial
MD Fischer, S Michalakis, B Wilhelm, D Zobor, R Muehlfriedel, S Kohl, ...
JAMA ophthalmology 138 (6), 643-651, 2020
1572020
Preparation of high-quality next-generation sequencing libraries from picogram quantities of target DNA
NJ Parkinson, S Maslau, B Ferneyhough, G Zhang, L Gregory, D Buck, ...
Genome research 22 (1), 125-133, 2012
1512012
AAV8 can induce innate and adaptive immune response in the primate eye
FF Reichel, DL Dauletbekov, R Klein, T Peters, GA Ochakovski, IP Seitz, ...
Molecular Therapy 25 (12), 2648-2660, 2017
1402017
Expression profiling reveals metabolic and structural components of extraocular muscles
MD Fischer, JR Gorospe, E Felder, S Bogdanovich, F Pedrosa-Domellof, ...
Physiological Genomics 9 (2), 71-84, 2002
1362002
A key role for cyclic nucleotide gated (CNG) channels in cGMP-related retinitis pigmentosa
F Paquet-Durand, S Beck, S Michalakis, T Goldmann, G Huber, ...
Human molecular genetics 20 (5), 941-947, 2011
1282011
Codon-optimized RPGR improves stability and efficacy of AAV8 gene therapy in two mouse models of X-linked retinitis pigmentosa
MD Fischer, ME McClements, CMF de la Camara, JS Bellingrath, ...
Molecular Therapy 25 (8), 1854-1865, 2017
1242017
Retinal gene therapy: surgical vector delivery in the translation to clinical trials
GA Ochakovski, KU Bartz-Schmidt, MD Fischer
Frontiers in neuroscience 11, 174, 2017
1082017
Definition of the unique human extraocular muscle allotype by expression profiling
MD Fischer, MT Budak, M Bakay, JR Gorospe, D Kjellgren, ...
Physiological genomics 22 (3), 283-291, 2005
1032005
Vision tests in the mouse: Functional phenotyping with electroretinography
N Tanimoto, RL Muehlfriedel, MD Fischer, E Fahl, P Humphries, M Biel, ...
Front Biosci 14, 2730-2737, 2009
932009
Superior retinal gene transfer and biodistribution profile of subretinal versus intravitreal delivery of AAV8 in nonhuman primates
IP Seitz, S Michalakis, B Wilhelm, FF Reichel, GA Ochakovski, E Zrenner, ...
Investigative ophthalmology & visual science 58 (13), 5792-5801, 2017
882017
Efficacy and safety of retinal gene therapy using adeno-associated virus vector for patients with choroideremia: a randomized clinical trial
MD Fischer, GA Ochakovski, B Beier, IP Seitz, Y Vaheb, C Kortuem, ...
JAMA ophthalmology 137 (11), 1247-1254, 2019
832019
Humoral immune response after intravitreal but not after subretinal AAV8 in primates and patients
FF Reichel, T Peters, B Wilhelm, M Biel, M Ueffing, B Wissinger, ...
Investigative Ophthalmology & Visual Science 59 (5), 1910-1915, 2018
762018
A new method to monitor visual field defects caused by photoreceptor degeneration by quantitative optical coherence tomography
MD Fischer, JC Fleischhauer, MC Gillies, FK Sutter, H Helbig, ...
Investigative ophthalmology & visual science 49 (8), 3617-3621, 2008
762008
Bone spicule pigment formation in retinitis pigmentosa: insights from a mouse model
GB Jaissle, CA May, SA Van De Pavert, A Wenzel, E Claes-May, A Gießl, ...
Graefe's Archive for Clinical and Experimental Ophthalmology 248 (8), 1063-1070, 2010
702010
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