Induction of cachexia in mice by systemically administered myostatin TA Zimmers, MV Davies, LG Koniaris, P Haynes, AF Esquela, ... Science 296 (5572), 1486-1488, 2002 | 1174 | 2002 |
Suppressor of cytokine signaling-3 (SOCS-3), a potential mediator of interleukin-6-dependent insulin resistance in hepatocytes JJ Senn, PJ Klover, IA Nowak, TA Zimmers, LG Koniaris, RW Furlanetto, ... Journal of Biological Chemistry 278 (16), 13740-13746, 2003 | 921 | 2003 |
Chronic exposure to interleukin-6 causes hepatic insulin resistance in mice PJ Klover, TA Zimmers, LG Koniaris, RA Mooney Diabetes 52 (11), 2784-2789, 2003 | 654 | 2003 |
IL-6 and PD-L1 antibody blockade combination therapy reduces tumour progression in murine models of pancreatic cancer TA Mace, R Shakya, JR Pitarresi, B Swanson, CW McQuinn, S Loftus, ... Gut 67 (2), 320-332, 2018 | 484 | 2018 |
JAK/STAT3 pathway inhibition blocks skeletal muscle wasting downstream of IL-6 and in experimental cancer cachexia A Bonetto, T Aydogdu, X Jin, Z Zhang, R Zhan, L Puzis, LG Koniaris, ... American Journal of Physiology-Endocrinology and Metabolism 303 (3), E410-E421, 2012 | 464 | 2012 |
Liver regeneration LG Koniaris, IH McKillop, SI Schwartz, TA Zimmers Journal of the American College of Surgeons 197 (4), 634-659, 2003 | 421 | 2003 |
STAT3 activation in skeletal muscle links muscle wasting and the acute phase response in cancer cachexia A Bonetto, T Aydogdu, N Kunzevitzky, DC Guttridge, S Khuri, LG Koniaris, ... PloS one 6 (7), e22538, 2011 | 393 | 2011 |
Characterization of growth-differentiation factor 15, a transforming growth factor β superfamily member induced following liver injury EC Hsiao, LG Koniaris, T Zimmers-Koniaris, SM Sebald, TV Huynh, ... Molecular and cellular biology 20 (10), 3742-3751, 2000 | 355 | 2000 |
Regulation of muscle mass by follistatin and activins SJ Lee, YS Lee, TA Zimmers, A Soleimani, MM Matzuk, K Tsuchida, ... Molecular endocrinology 24 (10), 1998-2008, 2010 | 338 | 2010 |
Acute inhibition of myostatin-family proteins preserves skeletal muscle in mouse models of cancer cachexia MEB Klimek, T Aydogdu, MJ Link, M Pons, LG Koniaris, TA Zimmers Biochemical and biophysical research communications 391 (3), 1548-1554, 2010 | 336 | 2010 |
Growth differentiation factor-15/macrophage inhibitory cytokine-1 induction after kidney and lung injury TA Zimmers, X Jin, EC Hsiao, SA McGrath, AF Esquela, LG Koniaris Shock 23 (6), 543-548, 2005 | 294 | 2005 |
BMP9 and BMP10 are critical for postnatal retinal vascular remodeling N Ricard, D Ciais, S Levet, M Subileau, C Mallet, TA Zimmers, SJ Lee, ... Blood, The Journal of the American Society of Hematology 119 (25), 6162-6171, 2012 | 293 | 2012 |
STAT3 in the systemic inflammation of cancer cachexia TA Zimmers, ML Fishel, A Bonetto Seminars in cell & developmental biology 54, 28-41, 2016 | 245 | 2016 |
Paradoxical effects of short‐and long‐term interleukin‐6 exposure on liver injury and repair X Jin, TA Zimmers, EA Perez, RH Pierce, Z Zhang, LG Koniaris Hepatology 43 (3), 474-484, 2006 | 245 | 2006 |
Chemotherapy-related cachexia is associated with mitochondrial depletion and the activation of ERK1/2 and p38 MAPKs R Barreto, DL Waning, H Gao, Y Liu, TA Zimmers, A Bonetto Oncotarget 7 (28), 43442, 2016 | 203 | 2016 |
Massive liver growth in mice induced by systemic interleukin 6 administration TA Zimmers, IH McKillop, RH Pierce, JY Yoo, LG Koniaris Hepatology 38 (2), 326-334, 2003 | 198 | 2003 |
Cancer and chemotherapy contribute to muscle loss by activating common signaling pathways R Barreto, G Mandili, FA Witzmann, F Novelli, TA Zimmers, A Bonetto Frontiers in physiology 7, 472, 2016 | 183 | 2016 |
Pancreas cancer‐associated weight loss AE Hendifar, MQB Petzel, TA Zimmers, CS Denlinger, LM Matrisian, ... The oncologist 24 (5), 691-701, 2019 | 172 | 2019 |
Mutations in the Trp-Ser-X-Trp-Ser motif of the erythropoietin receptor abolish processing, ligand binding, and activation of the receptor. A Yoshimura, T Zimmers, D Neumann, G Longmore, Y Yoshimura, ... Journal of Biological Chemistry 267 (16), 11619-11625, 1992 | 159 | 1992 |
Bone morphogenetic protein 9 (BMP9) controls lymphatic vessel maturation and valve formation S Levet, D Ciais, G Merdzhanova, C Mallet, TA Zimmers, SJ Lee, ... Blood, The Journal of the American Society of Hematology 122 (4), 598-607, 2013 | 155 | 2013 |