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paul klenerman
paul klenerman
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Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK
M Voysey, SAC Clemens, SA Madhi, LY Weckx, PM Folegatti, PK Aley, ...
The Lancet 397 (10269), 99-111, 2021
56132021
PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression
CL Day, DE Kaufmann, P Kiepiela, JA Brown, ES Moodley, S Reddy, ...
Nature 443 (7109), 350-354, 2006
33202006
Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: a preliminary report of a phase 1/2, single-blind, randomised controlled trial
PM Folegatti, KJ Ewer, PK Aley, B Angus, S Becker, ...
The Lancet 396 (10249), 467-478, 2020
28982020
The human cell atlas
A Regev, SA Teichmann, ES Lander, I Amit, C Benoist, E Birney, ...
elife 6, e27041, 2017
22062017
Memory CD8+ T cells vary in differentiation phenotype in different persistent virus infections
V Appay, PR Dunbar, M Callan, P Klenerman, GMA Gillespie, L Papagno, ...
Nature medicine 8 (4), 379-385, 2002
19672002
Guidelines for the use of flow cytometry and cell sorting in immunological studies
A Cossarizza, HD Chang, A Radbruch, A Acs, D Adam, S Adam‐Klages, ...
European journal of immunology 49 (10), 1457-1973, 2019
18982019
Safety and immunogenicity of ChAdOx1 nCoV-19 vaccine administered in a prime-boost regimen in young and old adults (COV002): a single-blind, randomised, controlled, phase 2/3 trial
MN Ramasamy, AM Minassian, KJ Ewer, AL Flaxman, PM Folegatti, ...
The Lancet 396 (10267), 1979-1993, 2020
17622020
Analysis of successful immune responses in persons infected with hepatitis C virus
F Lechner, DKH Wong, PR Dunbar, R Chapman, RT Chung, ...
The Journal of experimental medicine 191 (9), 1499-1512, 2000
16472000
Genetic mechanisms of critical illness in COVID-19
E Pairo-Castineira, S Clohisey, L Klaric, AD Bretherick, K Rawlik, D Pasko, ...
Nature 591 (7848), 92-98, 2021
14162021
Single-dose administration and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine: a pooled analysis of four …
M Voysey, SAC Clemens, SA Madhi, LY Weckx, PM Folegatti, PK Aley, ...
The Lancet 397 (10277), 881-891, 2021
14022021
Broad and strong memory CD4+ and CD8+ T cells induced by SARS-CoV-2 in UK convalescent individuals following COVID-19
Y Peng, AJ Mentzer, G Liu, X Yao, Z Yin, D Dong, W Dejnirattisai, ...
Nature immunology 21 (11), 1336-1345, 2020
12662020
Evidence of escape of SARS-CoV-2 variant B. 1.351 from natural and vaccine-induced sera
D Zhou, W Dejnirattisai, P Supasa, C Liu, AJ Mentzer, HM Ginn, Y Zhao, ...
Cell 184 (9), 2348-2361. e6, 2021
11862021
Dominant influence of HLA-B in mediating the potential co-evolution of HIV and HLA
P Kiepiela, AJ Leslie, I Honeyborne, D Ramduth, C Thobakgale, S Chetty, ...
Nature 432 (7018), 769-775, 2004
10112004
SARS-CoV-2 Omicron-B. 1.1. 529 leads to widespread escape from neutralizing antibody responses
W Dejnirattisai, J Huo, D Zhou, J Zahradník, P Supasa, C Liu, ...
Cell 185 (3), 467-484. e15, 2022
9902022
Positive selection of HIV-1 cytotoxic T lymphocyte escape variants during primary infection
DA Price, PJR Goulder, P Klenerman, AK Sewell, PJ Easterbrook, ...
Proceedings of the National Academy of Sciences 94 (5), 1890-1895, 1997
9181997
COVID-19 vaccine coverage in health-care workers in England and effectiveness of BNT162b2 mRNA vaccine against infection (SIREN): a prospective, multicentre, cohort study
VJ Hall, S Foulkes, A Saei, N Andrews, B Oguti, A Charlett, E Wellington, ...
The Lancet 397 (10286), 1725-1735, 2021
8082021
Mapping the human genetic architecture of COVID-19
Writing group Writing group leaders Pathak Gita A. 6 Andrews Shea J. 7 Kanai ...
Nature 600 (7889), 472-477, 2021
8042021
Reduced neutralization of SARS-CoV-2 B. 1.617 by vaccine and convalescent serum
C Liu, HM Ginn, W Dejnirattisai, P Supasa, B Wang, A Tuekprakhon, ...
Cell 184 (16), 4220-4236. e13, 2021
7812021
Oncostatin M drives intestinal inflammation and predicts response to tumor necrosis factor–neutralizing therapy in patients with inflammatory bowel disease
NR West, AN Hegazy, BMJ Owens, SJ Bullers, B Linggi, S Buonocore, ...
Nature medicine 23 (5), 579-589, 2017
7282017
Medium-term effects of SARS-CoV-2 infection on multiple vital organs, exercise capacity, cognition, quality of life and mental health, post-hospital discharge
B Raman, MP Cassar, EM Tunnicliffe, N Filippini, L Griffanti, ...
EClinicalMedicine 31, 2021
7182021
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