| Hypoxia and the extracellular matrix: drivers of tumour metastasis DM Gilkes, GL Semenza, D Wirtz Nature Reviews Cancer 14 (6), 430-439, 2014 | 1546 | 2014 |
| Hypoxia-inducible factors and RAB22A mediate formation of microvesicles that stimulate breast cancer invasion and metastasis T Wang, DM Gilkes, N Takano, L Xiang, W Luo, CJ Bishop, P Chaturvedi, ... Proceedings of the National Academy of Sciences 111 (31), E3234-E3242, 2014 | 559 | 2014 |
| Hypoxia-inducible factor 1 is a master regulator of breast cancer metastatic niche formation CCL Wong, DM Gilkes, H Zhang, J Chen, H Wei, P Chaturvedi, SI Fraley, ... Proceedings of the National Academy of Sciences 108 (39), 16369-16374, 2011 | 545 | 2011 |
| HIF-1 regulates CD47 expression in breast cancer cells to promote evasion of phagocytosis and maintenance of cancer stem cells H Zhang, H Lu, L Xiang, JW Bullen, C Zhang, D Samanta, DM Gilkes, ... Proceedings of the National Academy of Sciences 112 (45), E6215-E6223, 2015 | 413 | 2015 |
| ATM and Chk2‐dependent phosphorylation of MDMX contribute to p53 activation after DNA damage L Chen, DM Gilkes, Y Pan, WS Lane, J Chen The EMBO journal 24 (19), 3411-3422, 2005 | 353 | 2005 |
| Role of hypoxia-inducible factors in breast cancer metastasis DM Gilkes, GL Semenza Future oncology 9 (11), 1623-1636, 2013 | 328 | 2013 |
| Hypoxia-inducible factor–dependent breast cancer–mesenchymal stem cell bidirectional signaling promotes metastasis P Chaturvedi, DM Gilkes, CCL Wong, W Luo, H Zhang, H Wei, N Takano, ... The Journal of clinical investigation 123 (1), 2012 | 324 | 2012 |
| MDMX overexpression prevents p53 activation by the MDM2 inhibitor Nutlin B Hu, DM Gilkes, B Farooqi, SM Sebti, J Chen Journal of Biological Chemistry 281 (44), 33030-33035, 2006 | 300 | 2006 |
| BRCA1 and BRCA2 mutations and treatment strategies for breast cancer I Godet, DM Gilkes Integrative cancer science and therapeutics 4 (1), 10.15761/ICST. 1000228, 2017 | 277 | 2017 |
| Inhibitors of hypoxia-inducible factor 1 block breast cancer metastatic niche formation and lung metastasis CCL Wong, H Zhang, DM Gilkes, J Chen, H Wei, P Chaturvedi, ME Hubbi, ... Journal of molecular medicine 90, 803-815, 2012 | 267 | 2012 |
| Efficient p53 activation and apoptosis by simultaneous disruption of binding to MDM2 and MDMX B Hu, DM Gilkes, J Chen Cancer Research 67 (18), 8810-8817, 2007 | 267 | 2007 |
| Activation of dendritic cells via inhibition of Jak2/STAT3 signaling Y Nefedova, P Cheng, D Gilkes, M Blaskovich, AA Beg, SM Sebti, ... The Journal of Immunology 175 (7), 4338-4346, 2005 | 241 | 2005 |
| Hypoxia-inducible factor-dependent signaling between triple-negative breast cancer cells and mesenchymal stem cells promotes macrophage recruitment P Chaturvedi, DM Gilkes, N Takano, GL Semenza Proceedings of the National Academy of Sciences 111 (20), E2120-E2129, 2014 | 240 | 2014 |
| Hypoxia-inducible factors and cancer JC Jun, A Rathore, H Younas, D Gilkes, VY Polotsky Current sleep medicine reports 3, 1-10, 2017 | 235 | 2017 |
| Extracellular fluid viscosity enhances cell migration and cancer dissemination K Bera, A Kiepas, I Godet, Y Li, P Mehta, B Ifemembi, CD Paul, A Sen, ... Nature 611 (7935), 365-373, 2022 | 214 | 2022 |
| Fate-mapping post-hypoxic tumor cells reveals a ROS-resistant phenotype that promotes metastasis I Godet, YJ Shin, JA Ju, IC Ye, G Wang, DM Gilkes Nature communications 10 (1), 4862, 2019 | 214 | 2019 |
| Single-cell morphology encodes metastatic potential PH Wu, DM Gilkes, JM Phillip, A Narkar, TWT Cheng, J Marchand, ... Science advances 6 (4), eaaw6938, 2020 | 182 | 2020 |
| Synergistic IL-6 and IL-8 paracrine signalling pathway infers a strategy to inhibit tumour cell migration H Jayatilaka, P Tyle, JJ Chen, M Kwak, J Ju, HJ Kim, JSH Lee, PH Wu, ... Nature communications 8 (1), 15584, 2017 | 182 | 2017 |
| Sirtuin-7 inhibits the activity of hypoxia-inducible factors ME Hubbi, H Hu, DM Gilkes, GL Semenza Journal of Biological Chemistry 288 (29), 20768-20775, 2013 | 169 | 2013 |
| MDMX regulation of p53 response to ribosomal stress DM Gilkes, L Chen, J Chen The EMBO journal 25 (23), 5614-5625, 2006 | 161 | 2006 |
Inês GodetMemorial Sloan Kettering Cancer CenterDirección de correo verificada de mskcc.org
