Tau aggregation and its interplay with amyloid-β RM Nisbet, JC Polanco, LM Ittner, J Götz Acta neuropathologica 129, 207-220, 2015 | 406 | 2015 |
Inhibition of γ‐secretase causes increased secretion of amyloid precursor protein C‐terminal fragments in association with exosomes RA Sharples, LJ Vella, RM Nisbet, R Naylor, K Perez, KJ Barnham, ... The FASEB Journal 22 (5), 1469-1478, 2008 | 277 | 2008 |
The role of exosomes in the processing of proteins associated with neurodegenerative diseases LJ Vella, RA Sharples, RM Nisbet, R Cappai, AF Hill European Biophysics Journal 37, 323-332, 2008 | 265 | 2008 |
Ultrasound treatment of neurological diseases—current and emerging applications G Leinenga, C Langton, R Nisbet, J Goetz Nature Reviews Neurology 12 (3), 161-174, 2016 | 261 | 2016 |
Molecular pathogenesis of the tauopathies J Götz, G Halliday, RM Nisbet Annual Review of Pathology: Mechanisms of Disease 14 (1), 239-261, 2019 | 245 | 2019 |
Combined effects of scanning ultrasound and a tau-specific single chain antibody in a tau transgenic mouse model RM Nisbet, A Van der Jeugd, G Leinenga, HT Evans, PW Janowicz, ... Brain 140 (5), 1220-1230, 2017 | 200 | 2017 |
Co-immunoprecipitation with tau isoform-specific antibodies reveals distinct protein interactions and highlights a putative role for 2N tau in disease C Liu, X Song, R Nisbet, J Goetz Journal of Biological Chemistry 291 (15), 8173-8188, 2016 | 165 | 2016 |
March separate, strike together—Role of phosphorylated TAU in mitochondrial dysfunction in Alzheimer's disease A Eckert, R Nisbet, A Grimm, J Götz Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1842 (8 …, 2014 | 128 | 2014 |
Engineering of an anti‐epidermal growth factor receptor antibody to single chain format and labeling by sortase A‐mediated protein ligation MP Madej, G Coia, CC Williams, JM Caine, LA Pearce, R Attwood, ... Biotechnology and bioengineering 109 (6), 1461-1470, 2012 | 90 | 2012 |
Ultrasound-mediated blood-brain barrier opening enhances delivery of therapeutically relevant formats of a tau-specific antibody PW Janowicz, G Leinenga, J Götz, RM Nisbet Scientific reports 9 (1), 9255, 2019 | 73 | 2019 |
Amyloid-β and Tau in Alzheimer’s disease: novel pathomechanisms and non-pharmacological treatment strategies RM Nisbet, J Götz Journal of Alzheimer's Disease 64 (s1), S517-S527, 2018 | 59 | 2018 |
Conformation sensors that distinguish monomeric proteins from oligomers in live cells YM Ramdzan, RM Nisbet, J Miller, S Finkbeiner, AF Hill, DM Hatters Chemistry & biology 17 (4), 371-379, 2010 | 50 | 2010 |
Conformational detection of prion protein with biarsenical labeling and FlAsH fluorescence BM Coleman, RM Nisbet, S Han, R Cappai, DM Hatters, AF Hill Biochemical and biophysical research communications 380 (3), 564-568, 2009 | 46 | 2009 |
Residues surrounding the glycosylphosphatidylinositol anchor attachment site of PrP modulate prion infection: insight from the resistance of rabbits to prion disease RM Nisbet, CF Harrison, VA Lawson, CL Masters, R Cappai, AF Hill Journal of virology 84 (13), 6678-6686, 2010 | 35 | 2010 |
Comparison of alternative nucleophiles for Sortase A-mediated bioconjugation and application in neuronal cell labelling S Baer, J Nigro, MP Madej, RM Nisbet, R Suryadinata, G Coia, LPT Hong, ... Organic & Biomolecular Chemistry 12 (17), 2675-2685, 2014 | 29 | 2014 |
Current and emerging strategies for enhancing antibody delivery to the brain R Bajracharya, AC Caruso, LJ Vella, RM Nisbet Pharmaceutics 13 (12), 2014, 2021 | 27 | 2021 |
A sporadic Alzheimer's blood-brain barrier model for developing ultrasound-mediated delivery of Aducanumab and anti-Tau antibodies JM Wasielewska, JCS Chaves, RL Johnston, LA Milton, D Hernández, ... Theranostics 12 (16), 6826, 2022 | 26 | 2022 |
Structural studies of the tethered N‐terminus of the Alzheimer's disease amyloid‐β peptide RM Nisbet, SD Nuttall, R Robert, JM Caine, O Dolezal, M Hattarki, ... Proteins: Structure, Function, and Bioinformatics 81 (10), 1748-1758, 2013 | 24 | 2013 |
Central amyloid-β-specific single chain variable fragment ameliorates Aβ aggregation and neurotoxicity RM Nisbet, J Nigro, K Breheney, J Caine, MK Hattarki, SD Nuttall Protein Engineering, Design & Selection 26 (10), 571-580, 2013 | 23 | 2013 |
A novel antibody targeting tau phosphorylated at serine 235 detects neurofibrillary tangles D Brici, J Götz, RM Nisbet Journal of Alzheimer's Disease 61 (3), 899-905, 2018 | 18 | 2018 |