Histone acetyltransferases SY Roth, JM Denu, CD Allis Annual review of biochemistry 70 (1), 81-120, 2001 | 2778 | 2001 |
The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase BJ North, BL Marshall, MT Borra, JM Denu, E Verdin Molecular cell 11 (2), 437-444, 2003 | 1919 | 2003 |
Mechanism of human SIRT1 activation by resveratrol MT Borra, BC Smith, JM Denu Journal of Biological Chemistry 280 (17), 17187-17195, 2005 | 1342 | 2005 |
Sirt3 mediates reduction of oxidative damage and prevention of age-related hearing loss under caloric restriction S Someya, W Yu, WC Hallows, J Xu, JM Vann, C Leeuwenburgh, ... Cell 143 (5), 802-812, 2010 | 1274 | 2010 |
Specific and reversible inactivation of protein tyrosine phosphatases by hydrogen peroxide: evidence for a sulfenic acid intermediate and implications for redox regulation JM Denu, KG Tanner Biochemistry 37 (16), 5633-5642, 1998 | 1188 | 1998 |
Synergistic coupling of histone H3 phosphorylation and acetylation in response to epidermal growth factor stimulation P Cheung, KG Tanner, WL Cheung, P Sassone-Corsi, JM Denu, CD Allis Molecular cell 5 (6), 905-915, 2000 | 993 | 2000 |
Sirtuins deacetylate and activate mammalian acetyl-CoA synthetases WC Hallows, S Lee, JM Denu Proceedings of the National Academy of Sciences 103 (27), 10230-10235, 2006 | 949 | 2006 |
Silent information regulator 2 family of NAD- dependent histone/protein deacetylases generates a unique product, 1-O-acetyl-ADP-ribose KG Tanner, J Landry, R Sternglanz, JM Denu Proceedings of the National Academy of Sciences 97 (26), 14178-14182, 2000 | 742 | 2000 |
Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome AS Hebert, KE Dittenhafer-Reed, W Yu, DJ Bailey, ES Selen, ... Molecular cell 49 (1), 186-199, 2013 | 695 | 2013 |
Activation of the Protein Deacetylase SIRT6 by Long-chain Fatty Acids and Widespread Deacylation by Mammalian Sirtuins*♦ JL Feldman, J Baeza, JM Denu Journal of Biological Chemistry 288 (43), 31350-31356, 2013 | 683 | 2013 |
Circadian Clock NAD+ Cycle Drives Mitochondrial Oxidative Metabolism in Mice CB Peek, AH Affinati, KM Ramsey, HY Kuo, W Yu, LA Sena, O Ilkayeva, ... Science 342 (6158), 1243417, 2013 | 682 | 2013 |
Protein tyrosine phosphatases: mechanisms of catalysis and regulation JM Denu, JE Dixon Current opinion in chemical biology 2 (5), 633-641, 1998 | 557 | 1998 |
SIRT3 deacetylates mitochondrial 3-hydroxy-3-methylglutaryl CoA synthase 2 and regulates ketone body production T Shimazu, MD Hirschey, L Hua, KE Dittenhafer-Reed, B Schwer, ... Cell metabolism 12 (6), 654-661, 2010 | 538 | 2010 |
Form and function in protein dephosphorylation JM Denu, JA Stuckey, MA Saper, JE Dixon Cell 87 (3), 361-364, 1996 | 510 | 1996 |
Diet-microbiota interactions mediate global epigenetic programming in multiple host tissues KA Krautkramer, JH Kreznar, KA Romano, EI Vivas, GA Barrett-Wilt, ... Molecular cell 64 (5), 982-992, 2016 | 505 | 2016 |
Chemical mechanisms of histone lysine and arginine modifications BC Smith, JM Denu Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1789 (1), 45-57, 2009 | 488 | 2009 |
SIRT3 Protein Deacetylates Isocitrate Dehydrogenase 2 (IDH2) and Regulates Mitochondrial Redox Status*♦ W Yu, KE Dittenhafer-Reed, JM Denu Journal of Biological Chemistry 287 (17), 14078-14086, 2012 | 469 | 2012 |
Crystal structure of the dual specificity protein phosphatase VHR J Yuvaniyama, JM Denu, JE Dixon, MA Saper Science 272 (5266), 1328-1331, 1996 | 448 | 1996 |
Sirt3 promotes the urea cycle and fatty acid oxidation during dietary restriction WC Hallows, W Yu, BC Smith, MK Devires, JJ Ellinger, S Someya, ... Molecular cell 41 (2), 139-149, 2011 | 445 | 2011 |
Interactions between Roseburia intestinalis and diet modulate atherogenesis in a murine model K Kasahara, KA Krautkramer, E Org, KA Romano, RL Kerby, EI Vivas, ... Nature microbiology 3 (12), 1461-1471, 2018 | 411 | 2018 |