| ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition S Doll, B Proneth, YY Tyurina, E Panzilius, S Kobayashi, I Ingold, M Irmler, ... Nature chemical biology 13 (1), 91-98, 2017 | 2864 | 2017 |
| Increasing the efficiency of homology-directed repair for CRISPR-Cas9-induced precise gene editing in mammalian cells VT Chu, T Weber, B Wefers, W Wurst, S Sander, K Rajewsky, R Kühn Nature biotechnology 33 (5), 543-548, 2015 | 1479 | 2015 |
| Glutathione peroxidase 4 senses and translates oxidative stress into 12/15-lipoxygenase dependent-and AIF-mediated cell death A Seiler, M Schneider, H Förster, S Roth, EK Wirth, C Culmsee, N Plesnila, ... Cell metabolism 8 (3), 237-248, 2008 | 1400 | 2008 |
| Selenium utilization by GPX4 is required to prevent hydroperoxide-induced ferroptosis I Ingold, C Berndt, S Schmitt, S Doll, G Poschmann, K Buday, A Roveri, ... Cell 172 (3), 409-422. e21, 2018 | 1251 | 2018 |
| High-throughput discovery of novel developmental phenotypes ME Dickinson, AM Flenniken, X Ji, L Teboul, MD Wong, JK White, ... Nature 537 (7621), 508-514, 2016 | 1134 | 2016 |
| Impaired stress response and reduced anxiety in mice lacking a functional corticotropin-releasing hormone receptor 1 P Timpl, R Spanagel, I Sillaber, A Kresse, JMHM Reul, GK Stalla, ... Nature genetics 19 (2), 162-166, 1998 | 1113 | 1998 |
| Arc/Arg3. 1 is essential for the consolidation of synaptic plasticity and memories N Plath, O Ohana, B Dammermann, ML Errington, D Schmitz, C Gross, ... Neuron 52 (3), 437-444, 2006 | 978 | 2006 |
| Targeted disruption of the trkB neurotrophin receptor gene results in nervous system lesions and neonatal death R Klein, RJ Smeyne, W Wurst, LK Long, BA Auerbach, AL Joyner, ... Cell 75 (1), 113-122, 1993 | 856 | 1993 |
| The knockout mouse project Nature genetics 36 (9), 921-924, 2004 | 774 | 2004 |
| A humanized version of Foxp2 affects cortico-basal ganglia circuits in mice W Enard, S Gehre, K Hammerschmidt, SM Hölter, T Blass, M Somel, ... Cell 137 (5), 961-971, 2009 | 703 | 2009 |
| Neural plate patterning: upstream and downstream of the isthmic organizer W Wurst, L Bally-Cuif Nature Reviews Neuroscience 2 (2), 99-108, 2001 | 645 | 2001 |
| Multiple developmental defects in Engrailed-1 mutant mice: an early mid-hindbrain deletion and patterning defects in forelimbs and sternum W Wurst, AB Auerbach, AL Joyner Development 120 (7), 2065-2075, 1994 | 611 | 1994 |
| Essential role for mitochondrial thioredoxin reductase in hematopoiesis, heart development, and heart function M Conrad, C Jakupoglu, SG Moreno, S Lippl, A Banjac, M Schneider, ... Molecular and cellular biology 24 (21), 9414-9423, 2004 | 585 | 2004 |
| Aberrant methylation of t RNA s links cellular stress to neuro‐developmental disorders S Blanco, S Dietmann, JV Flores, S Hussain, C Kutter, P Humphreys, ... The EMBO journal 33 (18), 2020-2039, 2014 | 566 | 2014 |
| Hdac2 regulates the cardiac hypertrophic response by modulating Gsk3β activity CM Trivedi, Y Luo, Z Yin, M Zhang, W Zhu, T Wang, T Floss, M Goettlicher, ... Nature medicine 13 (3), 324-331, 2007 | 556 | 2007 |
| Limbic corticotropin-releasing hormone receptor 1 mediates anxiety-related behavior and hormonal adaptation to stress MB Müller, S Zimmermann, I Sillaber, TP Hagemeyer, JM Deussing, ... Nature neuroscience 6 (10), 1100-1107, 2003 | 556 | 2003 |
| A comparative phenotypic and genomic analysis of C57BL/6J and C57BL/6N mouse strains MM Simon, S Greenaway, JK White, H Fuchs, V Gailus-Durner, S Wells, ... Genome biology 14, 1-22, 2013 | 544 | 2013 |
| Rescue of the En-1 mutant phenotype by replacement of En-1 with En-2 M Hanks, W Wurst, L Anson-Cartwright, AB Auerbach, AL Joyner Science 269 (5224), 679-682, 1995 | 499 | 1995 |
| Loss of parkin or PINK1 function increases Drp1-dependent mitochondrial fragmentation AK Lutz, N Exner, ME Fett, JS Schlehe, K Kloos, K Lämmermann, ... Journal of Biological Chemistry 284 (34), 22938-22951, 2009 | 470 | 2009 |
| Parkinson's disease mutations in PINK1 result in decreased Complex I activity and deficient synaptic function VA Morais, P Verstreken, A Roethig, J Smet, A Snellinx, M Vanbrabant, ... EMBO molecular medicine 1 (2), 99-111, 2009 | 462 | 2009 |
Ralf KühnDirección de correo verificada de mdc-berlin.de
