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Michal Hocek
Michal Hocek
Institute of Organic Chemistry and Biochemistry ASCR
Dirección de correo verificada de natur.cuni.cz - Página principal
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C-Nucleosides: Synthetic Strategies and Biological Applications
M Hocek
Chemical reviews 109 (12), 6729-6764, 2009
4032009
Synthesis and cytostatic activity of substituted 6-phenylpurine bases and nucleosides: application of the Suzuki− Miyaura cross-coupling reactions of 6-chloropurine derivatives …
M Hocek, A Holý, I Votruba, H Dvořáková
Journal of Medicinal Chemistry 43 (9), 1817-1825, 2000
3002000
Cross-coupling reactions of nucleoside triphosphates followed by polymerase incorporation. Construction and applications of base-functionalized nucleic acids
M Hocek, M Fojta
Organic & biomolecular chemistry 6 (13), 2233-2241, 2008
1862008
Aminophenyl-and nitrophenyl-labeled nucleoside triphosphates: synthesis, enzymatic incorporation, and electrochemical detection
H Cahová, L Havran, P Brázdilová, H Pivonkova, R Pohl, M Fojta, ...
Angewandte Chemie-International Edition 47 (11), 2059-2062, 2008
1802008
Cytostatic 6-arylpurine nucleosides. 6. SAR in anti-HCV and cytostatic activity of extended series of 6-hetarylpurine ribonucleosides
M Hocek, P Nauš, R Pohl, I Votruba, PA Furman, PM Tharnish, MJ Otto
Journal of medicinal chemistry 48 (18), 5869-5873, 2005
1742005
Nucleobase modification as redox DNA labelling for electrochemical detection
M Hocek, M Fojta
Chemical Society Reviews 40 (12), 5802-5814, 2011
1732011
Synthesis of base-modified 2′-deoxyribonucleoside triphosphates and their use in enzymatic synthesis of modified DNA for applications in bioanalysis and chemical biology
M Hocek
The Journal of organic chemistry 79 (21), 9914-9921, 2014
1712014
Ferrocenylethynyl derivatives of nucleoside triphosphates: synthesis, incorporation, electrochemistry, and bioanalytical applications
P Brázdilová, M Vrábel, R Pohl, H Pivoňková, L Havran, M Hocek, M Fojta
Chemistry–A European Journal 13 (34), 9527-9533, 2007
1632007
An efficient method for the construction of functionalized DNA bearing amino acid groups through cross‐coupling reactions of nucleoside triphosphates followed by primer …
P Čapek, H Cahová, R Pohl, M Hocek, C Gloeckner, A Marx
Chemistry–A European Journal 13 (21), 6196-6203, 2007
1622007
Cross-coupling reactions of unprotected halopurine bases, nucleosides, nucleotides and nucleoside triphosphates with 4-boronophenylalanine in water. Synthesis of (purin-8-yl …
P Čapek, R Pohl, M Hocek
Organic & Biomolecular Chemistry 4 (11), 2278-2284, 2006
1542006
Direct C− H arylation of purines: Development of methodology and its use in regioselective synthesis of 2, 6, 8-trisubstituted purines
I Čerňa, R Pohl, B Klepetářová, M Hocek
Organic letters 8 (23), 5389-5392, 2006
1492006
Cytostatic 6-arylpurine nucleosides III. Synthesis and structure-activity relationship study in cytostatic activity of 6-aryl-, 6-hetaryl-and 6-benzylpurine ribonucleosides
M Hocek, A Holý, I Votruba, H Dvořáková
Collection of Czechoslovak Chemical Communications 66 (3), 483-499, 2001
1472001
A Rotational BODIPY Nucleotide: An Environment‐Sensitive Fluorescence‐Lifetime Probe for DNA Interactions and Applications in Live‐Cell Microscopy
D Dziuba, P Jurkiewicz, M Cebecauer, M Hof, M Hocek
Angewandte Chemie 128 (1), 182-186, 2016
1412016
Base‐Modified DNA Labeled by [Ru(bpy)3]2+ and [Os(bpy)3]2+ Complexes: Construction by Polymerase Incorporation of Modified Nucleoside Triphosphates …
M Vrabel, P Horakova, H Pivoňková, L Kalachova, H Černocká, H Cahova, ...
Chemistry–A European Journal 15 (5), 1144-1154, 2009
1372009
Synthesis and significant cytostatic activity of 7-hetaryl-7-deazaadenosines
A Bourderioux, P Nauš, P Perlíková, R Pohl, I Pichová, I Votruba, ...
Journal of medicinal chemistry 54 (15), 5498-5507, 2011
1332011
Direct polymerase synthesis of reactive aldehyde‐functionalized DNA and its conjugation and staining with hydrazines
V Raindlová, R Pohl, M Šanda, M Hocek
Angewandte Chemie 122 (6), 1082-1084, 2010
133*2010
6-(Het) aryl-7-deazapurine ribonucleosides as novel potent cytostatic agents
P Nauš, R Pohl, I Votruba, P Džubák, M Hajdúch, R Ameral, G Birkuš, ...
Journal of medicinal chemistry 53 (1), 460-470, 2010
1132010
Syntheses of Purines Bearing Carbon Substituents in Positions 2, 6 or 8 by Metal‐or Organometal‐Mediated C− C Bond‐Forming Reactions
M Hocek
European Journal of Organic Chemistry 2003 (2), 245-254, 2003
1132003
Pyrrolo[2,3‐d]pyrimidine (7‐deazapurine) as a privileged scaffold in design of antitumor and antiviral nucleosides
P Perlíková, M Hocek
Medicinal Research Reviews 37 (6), 1429-1460, 2017
1112017
An efficient synthesis of 2-substituted 6-methylpurine bases and nucleosides by Fe-or Pd-catalyzed cross-coupling reactions of 2, 6-dichloropurines
M Hocek, H Dvořáková
The Journal of Organic Chemistry 68 (14), 5773-5776, 2003
1102003
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