| RAG-1-deficient mice have no mature B and T lymphocytes P Mombaerts, J Iacomini, RS Johnson, K Herrup, S Tonegawa, ... Cell 68 (5), 869-877, 1992 | 3797 | 1992 |
| HIF-1α is essential for myeloid cell-mediated inflammation T Cramer, Y Yamanishi, BE Clausen, I Förster, R Pawlinski, N Mackman, ... Cell 112 (5), 645-657, 2003 | 2475 | 2003 |
| HIF‐1α is required for solid tumor formation and embryonic vascularization HE Ryan, J Lo, RS Johnson The EMBO journal, 1998 | 2045 | 1998 |
| HIF1α and HIF2α: sibling rivalry in hypoxic tumour growth and progression B Keith, RS Johnson, MC Simon Nature Reviews Cancer 12 (1), 9-22, 2012 | 2029 | 2012 |
| NF-κB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1α J Rius, M Guma, C Schachtrup, K Akassoglou, AS Zinkernagel, V Nizet, ... Nature 453 (7196), 807-811, 2008 | 1863 | 2008 |
| Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene E Araki, MA Lipes, ME Patti, JC Brüning, B Haag III, RS Johnson, ... Nature 372 (6502), 186-190, 1994 | 1733 | 1994 |
| HIF1α induces the recruitment of bone marrow-derived vascular modulatory cells to regulate tumor angiogenesis and invasion R Du, KV Lu, C Petritsch, P Liu, R Ganss, E Passegué, H Song, ... Cancer cell 13 (3), 206-220, 2008 | 1437 | 2008 |
| The IKKβ subunit of IκB kinase (IKK) is essential for nuclear factor κB activation and prevention of apoptosis ZW Li, W Chu, Y Hu, M Delhase, T Deerinck, M Ellisman, R Johnson, ... The Journal of experimental medicine 189 (11), 1839-1845, 1999 | 1258 | 1999 |
| Loss of PTEN facilitates HIF-1-mediated gene expression W Zundel, C Schindler, D Haas-Kogan, A Koong, F Kaper, E Chen, ... Genes & development 14 (4), 391-396, 2000 | 1230 | 2000 |
| Biology of HIF-1α A Weidemann, RS Johnson Cell Death & Differentiation 15 (4), 621-627, 2008 | 1224 | 2008 |
| HIF transcription factors, inflammation, and immunity A Palazon, AW Goldrath, V Nizet, RS Johnson Immunity 41 (4), 518-528, 2014 | 1175 | 2014 |
| Hypoxia promotes fibrogenesis in vivo via HIF-1 stimulation of epithelial-to-mesenchymal transition DF Higgins, K Kimura, WM Bernhardt, N Shrimanker, Y Akai, ... The Journal of clinical investigation 117 (12), 3810-3820, 2007 | 1157 | 2007 |
| Abnormal morphogenesis but intact IKK activation in mice lacking the IKKα subunit of IκB kinase Y Hu, V Baud, M Delhase, P Zhang, T Deerinck, M Ellisman, R Johnson, ... Science 284 (5412), 316-320, 1999 | 1129 | 1999 |
| Hypoxia-inducible factor-1α is a positive factor in solid tumor growth HE Ryan, M Poloni, W McNulty, D Elson, M Gassmann, JM Arbeit, ... Cancer research 60 (15), 4010-4015, 2000 | 1087 | 2000 |
| Regulation of the HIF-1α level is essential for hematopoietic stem cells K Takubo, N Goda, W Yamada, H Iriuchishima, E Ikeda, Y Kubota, ... Cell stem cell 7 (3), 391-402, 2010 | 1065 | 2010 |
| Hypoxia in cartilage: HIF-1α is essential for chondrocyte growth arrest and survival E Schipani, HE Ryan, S Didrickson, T Kobayashi, M Knight, RS Johnson Genes & development 15 (21), 2865-2876, 2001 | 977 | 2001 |
| Uncoupling of obesity from insulin resistance through a targeted mutation in aP2, the adipocyte fatty acid binding protein GS Hotamisligil, RS Johnson, RJ Distel, R Ellis, VE Papaioannou, ... Science 274 (5291), 1377-1379, 1996 | 976 | 1996 |
| Hypoxia: a key regulator of angiogenesis in cancer D Liao, RS Johnson Cancer and Metastasis Reviews 26, 281-290, 2007 | 961 | 2007 |
| Hypoxia-induced neutrophil survival is mediated by HIF-1α–dependent NF-κB activity SR Walmsley, C Print, N Farahi, C Peyssonnaux, RS Johnson, T Cramer, ... The Journal of experimental medicine 201 (1), 105-115, 2005 | 946 | 2005 |
| The hypoxia-inducible factor α pathway couples angiogenesis to osteogenesis during skeletal development Y Wang, C Wan, L Deng, X Liu, X Cao, SR Gilbert, ML Bouxsein, ... The Journal of clinical investigation 117 (6), 1616-1626, 2007 | 888 | 2007 |
