| Loss of PLA2G6 leads to elevated mitochondrial lipid peroxidation and mitochondrial dysfunction KJ Kinghorn, JI Castillo-Quan, F Bartolome, PR Angelova, L Li, S Pope, ... Brain 138 (7), 1801-1816, 2015 | 192 | 2015 |
| Pathogenic VCP mutations induce mitochondrial uncoupling and reduced ATP levels F Bartolome, HC Wu, VS Burchell, E Preza, S Wray, CJ Mahoney, NC Fox, ... Neuron 78 (1), 57-64, 2013 | 180 | 2013 |
| Measurement of mitochondrial NADH and FAD autofluorescence in live cells F Bartolomé, AY Abramov Mitochondrial Medicine: Volume I, Probing Mitochondrial Function, 263-270, 2015 | 171 | 2015 |
| Early diagnosis of mild cognitive impairment and Alzheimer's disease based on salivary lactoferrin E Carro, F Bartolomé, F Bermejo-Pareja, A Villarejo-Galende, JA Molina, ... Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring 8, 131-138, 2017 | 167 | 2017 |
| Mutations in HPCA cause autosomal-recessive primary isolated dystonia G Charlesworth, PR Angelova, F Bartolomé-Robledo, M Ryten, ... The American Journal of Human Genetics 96 (4), 657-665, 2015 | 98 | 2015 |
| Decreased salivary lactoferrin levels are specific to Alzheimer's disease M González-Sánchez, F Bartolome, D Antequera, V Puertas-Martín, ... EBioMedicine 57, 2020 | 89 | 2020 |
| Amyloid β-induced impairments on mitochondrial dynamics, hippocampal neurogenesis, and memory are restored by phosphodiesterase 7 inhibition F Bartolome, M de la Cueva, C Pascual, D Antequera, T Fernandez, C Gil, ... Alzheimer's Research & Therapy 10, 1-15, 2018 | 81 | 2018 |
| Motor neuron preservation and decrease of in vivo TDP-43 phosphorylation by protein CK-1δ kinase inhibitor treatment L Martínez-González, C Rodríguez-Cueto, D Cabezudo, F Bartolomé, ... Scientific reports 10 (1), 4449, 2020 | 67 | 2020 |
| Pathogenic p62/SQSTM1 mutations impair energy metabolism through limitation of mitochondrial substrates F Bartolome, N Esteras, A Martin-Requero, C Boutoleau-Bretonniere, ... Scientific reports 7 (1), 1666, 2017 | 66 | 2017 |
| Enhanced proteasome-dependent degradation of the CDK inhibitor p27kip1 in immortalized lymphocytes from Alzheimer's dementia patients U Munoz, F Bartolomé, F Bermejo, Á Martín-Requero Neurobiology of aging 29 (10), 1474-1484, 2008 | 58 | 2008 |
| Kynurenic acid levels are increased in the CSF of Alzheimer’s disease patients M González-Sánchez, J Jiménez, A Narváez, D Antequera, ... Biomolecules 10 (4), 571, 2020 | 54 | 2020 |
| Salivary lactoferrin as biomarker for Alzheimer's disease: Brain‐immunity interactions F Bermejo‐Pareja, T Del Ser, M Valentí, M de la Fuente, F Bartolome, ... Alzheimer's & Dementia 16 (8), 1196-1204, 2020 | 53 | 2020 |
| HMG-CoA reductase inhibitor simvastatin inhibits cell cycle progression at the G1/S checkpoint in immortalized lymphocytes from Alzheimer's disease patients independently of … SG Sala, U Munoz, F Bartolome, F Bermejo, Á Martín-Requero Journal of Pharmacology and Experimental Therapeutics 324 (1), 352-359, 2008 | 51 | 2008 |
| Amyloid-β impairs mitochondrial dynamics and autophagy in Alzheimer’s disease experimental models M de la Cueva, D Antequera, L Ordoñez-Gutierrez, F Wandosell, ... Scientific Reports 12 (1), 10092, 2022 | 44 | 2022 |
| Mutations in valosin-containing protein (VCP) decrease ADP/ATP translocation across the mitochondrial membrane and impair energy metabolism in human neurons MHR Ludtmann, C Arber, F Bartolome, M de Vicente, E Preza, E Carro, ... Journal of Biological Chemistry 292 (21), 8907-8917, 2017 | 42 | 2017 |
| Recapitulation of pathological TDP-43 features in immortalized lymphocytes from sporadic ALS patients D Posa, L Martínez-González, F Bartolomé, S Nagaraj, G Porras, ... Molecular neurobiology 56, 2424-2432, 2019 | 36 | 2019 |
| Altered cell cycle‐related gene expression in brain and lymphocytes from a transgenic mouse model of Alzheimer’s disease [amyloid precursor protein/presenilin 1 (PS1)] N Esteras, F Bartolomé, C Alquézar, D Antequera, U Munoz, E Carro, ... European Journal of Neuroscience 36 (5), 2609-2618, 2012 | 34 | 2012 |
| Obesity and neuroinflammatory phenotype in mice lacking endothelial megalin F Bartolome, D Antequera, E Tavares, C Pascual, R Maldonado, ... Journal of Neuroinflammation 14, 1-10, 2017 | 33 | 2017 |
| From kinase inhibitors to multitarget ligands as powerful drug leads for Alzheimer's disease using protein‐templated synthesis V Nozal, A García‐Rubia, EP Cuevas, C Pérez, C Tosat‐Bitrián, ... Angewandte Chemie 133 (35), 19493-19503, 2021 | 30 | 2021 |
| Alteration in cell cycle-related proteins in lymphoblasts from carriers of the c. 709-1G> A PGRN mutation associated with FTLD-TDP dementia C Alquezar, N Esteras, F Bartolomé, JJ Merino, A Alzualde, AL de Munain, ... Neurobiology of aging 33 (2), 429. e7-429. e20, 2012 | 27 | 2012 |
