microRNA-7 is a novel inhibitor of YY1 contributing to colorectal tumorigenesis N Zhang, X Li, CW Wu, Y Dong, M Cai, MTS Mok, H Wang, J Chen, ... Oncogene 32 (42), 5078-5088, 2013 | 243 | 2013 |
Reconstruction of enhancer–target networks in 935 samples of human primary cells, tissues and cell lines Q Cao, C Anyansi, X Hu, L Xu, L Xiong, W Tang, MTS Mok, C Cheng, ... Nature genetics 49 (10), 1428-1436, 2017 | 224 | 2017 |
Targeting monocyte-intrinsic enhancer reprogramming improves immunotherapy efficacy in hepatocellular carcinoma M Liu, J Zhou, X Liu, Y Feng, W Yang, F Wu, OKW Cheung, H Sun, ... Gut 69 (2), 365-379, 2020 | 150 | 2020 |
An inflammatory-CCRK circuitry drives mTORC1-dependent metabolic and immunosuppressive reprogramming in obesity-associated hepatocellular carcinoma H Sun, W Yang, Y Tian, X Zeng, J Zhou, MTS Mok, W Tang, Y Feng, L Xu, ... Nature communications 9 (1), 5214, 2018 | 95 | 2018 |
Aberrant enhancer hypomethylation contributes to hepatic carcinogenesis through global transcriptional reprogramming L Xiong, F Wu, Q Wu, L Xu, OK Cheung, W Kang, MT Mok, LLM Szeto, ... Nature communications 10 (1), 335, 2019 | 88 | 2019 |
Identification of BRCA1 missense substitutions that confer partial functional activity: potential moderate risk variants? PK Lovelock, AB Spurdle, MTS Mok, DJ Farrugia, SR Lakhani, S Healey, ... Breast Cancer Research 9, 1-13, 2007 | 74 | 2007 |
Epigenetic activation of Wnt/β-catenin signaling in NAFLD-associated hepatocarcinogenesis Y Tian, MTS Mok, P Yang, ASL Cheng Cancers 8 (8), 76, 2016 | 56 | 2016 |
Aberrant cholesterol metabolic signaling impairs antitumor immunosurveillance through natural killer T cell dysfunction in obese liver W Tang, J Zhou, W Yang, Y Feng, H Wu, MTS Mok, L Zhang, Z Liang, ... Cellular & Molecular Immunology 19 (7), 834-847, 2022 | 55 | 2022 |
Stimulation of in vivo nuclear transport dynamics of actin and its co-factors IQGAP1 and Rac1 in response to DNA replication stress MA Johnson, M Sharma, MTS Mok, BR Henderson Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1833 (10), 2334-2347, 2013 | 52 | 2013 |
CCRK is a novel signalling hub exploitable in cancer immunotherapy MT Mok, J Zhou, W Tang, X Zeng, AW Oliver, SE Ward, AS Cheng Pharmacology & therapeutics 186, 138-151, 2018 | 50 | 2018 |
Inhibitory role of Smad7 in hepatocarcinogenesis in mice and in vitro J Wang, J Zhao, ESH Chu, MTS Mok, MYY Go, K Man, R Heuchel, ... The Journal of pathology 230 (4), 441-452, 2013 | 46 | 2013 |
Androgen receptor drives hepatocellular carcinogenesis by activating enhancer of zeste homolog 2-mediated Wnt/β-catenin signaling H Song, Z Yu, X Sun, J Feng, Q Yu, H Khan, X Zhu, L Huang, M Li, ... EBioMedicine 35, 155-166, 2018 | 44 | 2018 |
Mitochondrial targeting of adenomatous polyposis coli protein is stimulated by truncating cancer mutations: regulation of Bcl-2 and implications for cell survival M Brocardo, Y Lei, A Tighe, SS Taylor, MTS Mok, BR Henderson Journal of Biological Chemistry 283 (9), 5950-5959, 2008 | 43 | 2008 |
Loss of tumor suppressor IGFBP4 drives epigenetic reprogramming in hepatic carcinogenesis YY Lee, MTS Mok, W Kang, W Yang, W Tang, F Wu, L Xu, M Yan, Z Yu, ... Nucleic acids research 46 (17), 8832-8847, 2018 | 37 | 2018 |
The anti-diabetic drug exenatide, a glucagon-like peptide-1 receptor agonist, counteracts hepatocarcinogenesis through cAMP–PKA–EGFR–STAT3 axis M Zhou, MTS Mok, H Sun, AW Chan, Y Huang, ASL Cheng, G Xu Oncogene 36 (29), 4135-4149, 2017 | 37 | 2017 |
Regulation of β-catenin trafficking to the membrane in living cells M Johnson, M Sharma, C Jamieson, JM Henderson, MTS Mok, L Bendall, ... Cellular signalling 21 (2), 339-348, 2009 | 37 | 2009 |
Cell cycle-related kinase reprograms the liver immune microenvironment to promote cancer metastasis X Zeng, J Zhou, Z Xiong, H Sun, W Yang, MTS Mok, J Wang, J Li, M Liu, ... Cellular & Molecular Immunology 18 (4), 1005-1015, 2021 | 35 | 2021 |
Truncated HBx‐dependent silencing of GAS2 promotes hepatocarcinogenesis through deregulation of cell cycle, senescence and p53‐mediated apoptosis R Zhu, MTS Mok, W Kang, SSK Lau, WK Yip, Y Chen, PBS Lai, ... The Journal of Pathology 237 (1), 38-49, 2015 | 34 | 2015 |
A comparison of BRCA1 nuclear localization with 14 DNA damage response proteins and domains: identification of specific differences between BRCA1 and 53BP1 at DNA damage … MTS Mok, BR Henderson Cellular signalling 22 (1), 47-56, 2010 | 32 | 2010 |
Mouse mammary tumor virus‐like env sequences in human breast cancer MTS Mok, JS Lawson, BJ Iacopetta, NJ Whitaker International journal of cancer 122 (12), 2864-2870, 2008 | 31 | 2008 |