| Structure, mechanism and crystallographic fragment screening of the SARS-CoV-2 NSP13 helicase JA Newman, A Douangamath, S Yadzani, Y Yosaatmadja, A Aimon, ... Nature Communications 12 (1), 4848, 2021 | 181 | 2021 |
| Binding mode of the breakthrough inhibitor AZD9291 to epidermal growth factor receptor revealed Y Yosaatmadja, S Silva, JM Dickson, AV Patterson, JB Smaill, ... Journal of structural biology 192 (3), 539-544, 2015 | 140 | 2015 |
| TAS‐120 cancer target binding: defining reactivity and revealing the first fibroblast growth factor receptor 1 (FGFR1) irreversible structure M Kalyukina, Y Yosaatmadja, MJ Middleditch, AV Patterson, JB Smaill, ... ChemMedChem 14 (4), 494-500, 2019 | 108 | 2019 |
| Crystal structures of three classes of non-steroidal anti-inflammatory drugs in complex with aldo-keto reductase 1C3 JU Flanagan, Y Yosaatmadja, RM Teague, MZL Chai, AP Turnbull, ... Public Library of Science 7 (8), e43965, 2012 | 70 | 2012 |
| Radiation damage and racemic protein crystallography reveal the unique structure of the GASA/snakin protein superfamily H Yeung, CJ Squire, Y Yosaatmadja, S Panjikar, G López, A Molina, ... Angewandte Chemie 128 (28), 8062-8065, 2016 | 63 | 2016 |
| Characterization of the SARS-CoV-2 ExoN (nsp14ExoN–nsp10) complex: implications for its role in viral genome stability and inhibitor identification HT Baddock, S Brolih, Y Yosaatmadja, M Ratnaweera, M Bielinski, ... Nucleic acids research 50 (3), 1484-1500, 2022 | 56 | 2022 |
| The interaction of human neuroglobin with hydrogen sulphide T Brittain, Y Yosaatmadja, K Henty IUBMB life 60 (2), 135-138, 2008 | 54 | 2008 |
| Structures of human peroxiredoxin 3 suggest self-chaperoning assembly that maintains catalytic state NA Yewdall, H Venugopal, A Desfosses, V Abrishami, Y Yosaatmadja, ... Structure 24 (7), 1120-1129, 2016 | 53 | 2016 |
| The SNM1A DNA repair nuclease HT Baddock, Y Yosaatmadja, JA Newman, CJ Schofield, O Gileadi, ... DNA repair 95, 102941, 2020 | 34 | 2020 |
| Mechanistic and evolutionary insights from the reciprocal promiscuity of two pyridoxal phosphate-dependent enzymes VWC Soo, Y Yosaatmadja, CJ Squire, WM Patrick Journal of Biological Chemistry 291 (38), 19873-19887, 2016 | 33 | 2016 |
| Crystal structures and fragment screening of SARS-CoV-2 NSP14 reveal details of exoribonuclease activation and mRNA capping and provide starting points for antiviral drug … N Imprachim, Y Yosaatmadja, JA Newman Nucleic Acids Research 51 (1), 475-487, 2023 | 32 | 2023 |
| 2-Oxo-3, 4-dihydropyrimido [4, 5-d] pyrimidinyl derivatives as new irreversible pan fibroblast growth factor receptor (FGFR) inhibitors X Li, CP Guise, R Taghipouran, Y Yosaatmadja, A Ashoorzadeh, WK Paik, ... European Journal of Medicinal Chemistry 135, 531-543, 2017 | 29 | 2017 |
| Harnessing ester bond chemistry for protein ligation PG Young, Y Yosaatmadja, PWR Harris, IKH Leung, EN Baker, CJ Squire Chemical communications 53 (9), 1502-1505, 2017 | 28 | 2017 |
| The 1.65 Å resolution structure of the complex of AZD4547 with the kinase domain of FGFR1 displays exquisite molecular recognition Y Yosaatmadja, AV Patterson, JB Smaill, CJ Squire Acta Crystallographica Section D: Biological Crystallography 71 (3), 525-533, 2015 | 27 | 2015 |
| Structural and mechanistic insights into the Artemis endonuclease and strategies for its inhibition Y Yosaatmadja, HT Baddock, JA Newman, M Bielinski, AE Gavard, ... Nucleic acids research 49 (16), 9310-9326, 2021 | 26 | 2021 |
| Rotational freedom, steric hindrance, and protein dynamics explain BLU554 selectivity for the hinge cysteine of FGFR4 X Lin, Y Yosaatmadja, M Kalyukina, MJ Middleditch, Z Zhang, X Lu, ... ACS Medicinal Chemistry Letters 10 (8), 1180-1186, 2019 | 22 | 2019 |
| A phosphate binding pocket is a key determinant of exo-versus endo-nucleolytic activity in the SNM1 nuclease family HT Baddock, JA Newman, Y Yosaatmadja, M Bielinski, CJ Schofield, ... Nucleic acids research 49 (16), 9294-9309, 2021 | 15 | 2021 |
| Structure of AKR1C3 with 3-phenoxybenzoic acid bound VJ Jackson, Y Yosaatmadja, JU Flanagan, CJ Squire Acta Crystallographica Section F: Structural Biology and Crystallization …, 2012 | 14 | 2012 |
| 1.85 angstrom structure of EGFR kinase domain with gefitinib Y Yosaatmadja, C Squire, C McKeage, M Flanagan Protein Data Bank. Available online: https://www. rcsb. org/structure/4WKQ …, 2014 | 12 | 2014 |
| Characterisation of the SARS-CoV-2 ExoN (nsp14ExoN-nsp10) complex: implications for its role in viral genome stability and inhibitor identification. bioRxiv; 2020 August 13 … HT Baddock, S Brolih, Y Yosaatmadja, M Ratnaweera, M Bielinski, ... | 7 | |
Christopher J SquireUniversity of AucklandDirección de correo verificada de auckland.ac.nz