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Sebastian Leth-Petersen
Sebastian Leth-Petersen
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Dirección de correo verificada de sund.ku.dk - Página principal
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Synthesis and Structure–Activity Relationships of N-Benzyl Phenethylamines as 5-HT2A/2C Agonists
M Hansen, K Phonekeo, JS Paine, S Leth-Petersen, M Begtrup, ...
ACS chemical neuroscience 5 (3), 243-249, 2014
1302014
Triazoloquinazolines as a novel class of phosphodiesterase 10A (PDE10A) inhibitors
J Kehler, A Ritzen, M Langgård, SL Petersen, MM Farah, C Bundgaard, ...
Bioorganic & medicinal chemistry letters 21 (12), 3738-3742, 2011
632011
Detailed characterization of the in vitro pharmacological and pharmacokinetic properties of N-(2-hydroxybenzyl)-2, 5-dimethoxy-4-cyanophenylethylamine (25CN-NBOH), a highly …
AA Jensen, JD McCorvy, S Leth-Petersen, C Bundgaard, G Liebscher, ...
Journal of Pharmacology and Experimental Therapeutics 361 (3), 441-453, 2017
512017
Metabolic fate of hallucinogenic NBOMes
S Leth-Petersen, C Gabel-Jensen, N Gillings, S Lehel, HD Hansen, ...
Chemical research in toxicology 29 (1), 96-100, 2016
512016
Characterization of the hepatic cytochrome P450 enzymes involved in the metabolism of 25I‐NBOMe and 25I‐NBOH
LM Nielsen, NB Holm, S Leth‐Petersen, JL Kristensen, L Olsen, K Linnet
Drug testing and analysis 9 (5), 671-679, 2017
452017
Correlating the Metabolic Stability of Psychedelic 5-HT2A Agonists with Anecdotal Reports of Human Oral Bioavailability
S Leth-Petersen, C Bundgaard, M Hansen, MA Carnerup, J Kehler, ...
Neurochemical research 39, 2018-2023, 2014
312014
The importance of small polar radiometabolites in molecular neuroimaging: A PET study with [11C]Cimbi-36 labeled in two positions
A Johansen, HD Hansen, C Svarer, S Lehel, S Leth-Petersen, ...
Journal of Cerebral Blood Flow & Metabolism 38 (4), 659-668, 2018
282018
N-Methylanilide and N-methylbenzamide derivatives as phosphodiesterase 10A (PDE10A) inhibitors
JP Kilburn, J Kehler, M Langgård, MN Erichsen, S Leth-Petersen, ...
Bioorganic & medicinal chemistry 21 (19), 6053-6062, 2013
252013
5-HT2A/5-HT2C Receptor Pharmacology and Intrinsic Clearance of N-Benzylphenethylamines Modified at the Primary Site of Metabolism
S Leth-Petersen, IN Petersen, AA Jensen, C Bundgaard, M Bæk, J Kehler, ...
ACS chemical neuroscience 7 (11), 1614-1619, 2016
172016
Structure-Activity Relationships of Constrained Phenylethylamine Ligands for the Serotonin 5-HT2 Receptors
V Isberg, J Paine, S Leth-Petersen, JL Kristensen, DE Gloriam
PLoS One 8 (11), e78515, 2013
172013
5-HT2A agonists for use in treatment of depression
JL Kristensen, AA Jensen, E Märcher-rørsted, LP Sebastian
US Patent 11,246,860, 2022
112022
Accelerating preclinical PET-screening: reductive amination with [11 C] methoxybenzaldehydes
MM Herth, S Leth-Petersen, S Lehel, M Hansen, GM Knudsen, N Gillings, ...
RSC Advances 4 (41), 21347-21350, 2014
102014
Locomotor effects of 3, 4-methylenedioxymethamphetamine (MDMA) and its deuterated form in mice: psychostimulant effects, stereotypy, and sensitization
MD Berquist, S Leth-Petersen, JL Kristensen, WE Fantegrossi
Psychopharmacology 237, 431-442, 2020
92020
In vivo effects of 3, 4-methylenedioxymethamphetamine (MDMA) and its deuterated form in rodents: Drug discrimination and thermoregulation
MD Berquist, S Leth-Petersen, JL Kristensen, WE Fantegrossi
Drug and Alcohol Dependence 208, 107850, 2020
52020
Synthesis, radiofluorination, and preliminary evaluation of the potential 5‐HT2A receptor agonists [18F]Cimbi‐92 and [18F]Cimbi‐150
FG Edgar, HD Hansen, S Leth‐Petersen, A Ettrup, JL Kristensen, ...
Journal of Labelled Compounds and Radiopharmaceuticals 60 (12), 586-591, 2017
42017
5-HT2A agonists for use in treatment of depression
JL Kristensen, AA Jensen, E Märcher-rørsted, LP Sebastian
US Patent 11,642,336, 2023
12023
5-HT2A agonists for use in treatment of depression
JL Kristensen, AA Jensen, E Märcher-rørsted, LP Sebastian
US Patent 11,633,390, 2023
12023
5-HT2A Agonists for Use in Treatment of Depression
JL Kristensen, AA Jensen, EM Rorsted, SL Petersen
US2022062257. Google Scholar There is no corresponding record for this reference, 2022
12022
An Improved Radiolabelling Strategy for the 5-HT2A Agonist,[C-11] Cimbi-36
N Gillings, S Lehel, M Herth, S Leth-Petersen, J Madsen, C Gabel-Jensen, ...
JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS 58, S296-S296, 2015
12015
Effects of serotonergic hallucinogen R(−)‐2,5‐Dimethoxy‐4‐iodoamphetamine (DOI) on temporal discrimination in mice
MP Trahan, S Leth‐Petersen, WE Fantegrossi
The FASEB Journal 31, 1059.7-1059.7, 2017
2017
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