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Armando Rossello
Armando Rossello
Full Professor of Medicinal Chemistry, Università di Pisa, Dipartimento di Farmacia
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Synthesis, antifungal activity, and molecular modeling studies of new inverted oxime ethers of oxiconazole
A Rossello, S Bertini, A Lapucci, M Macchia, A Martinelli, S Rapposelli, ...
Journal of Medicinal Chemistry 45 (22), 4903-4912, 2002
1782002
The ALCAM shedding by the metalloprotease ADAM17/TACE is involved in motility of ovarian carcinoma cells
O Rosso, T Piazza, I Bongarzone, A Rossello, D Mezzanzanica, ...
Molecular Cancer Research 5 (12), 1246-1253, 2007
1422007
Matrix metalloproteinase inhibitors: new challenges in the era of post broad-spectrum inhibitors
E Nuti, T Tuccinardi, A Rossello
Current pharmaceutical design 13 (20), 2087-2100, 2007
1402007
Combining the tail and the ring approaches for obtaining potent and isoform-selective carbonic anhydrase inhibitors: solution and X-ray crystallographic studies
M Bozdag, M Ferraroni, E Nuti, D Vullo, A Rossello, F Carta, A Scozzafava, ...
Bioorganic & Medicinal Chemistry 22 (1), 334-340, 2014
1162014
New N-arylsulfonyl-N-alkoxyaminoacetohydroxamic acids as selective inhibitors of gelatinase A (MMP-2)
A Rossello, E Nuti, E Orlandini, P Carelli, S Rapposelli, M Macchia, ...
Bioorganic & medicinal chemistry 12 (9), 2441-2450, 2004
1042004
Amber force field implementation, molecular modelling study, synthesis and MMP-1/MMP-2 inhibition profile of (R)-and (S)-N-hydroxy-2-(N-isopropoxybiphenyl-4-ylsulfonamido)-3 …
T Tuccinardi, A Martinelli, E Nuti, P Carelli, F Balzano, G Uccello-Barretta, ...
Bioorganic & medicinal chemistry 14 (12), 4260-4276, 2006
992006
Strategies to target ADAM17 in disease: from its discovery to the iRhom revolution
M Calligaris, D Cuffaro, S Bonelli, DP Spanò, A Rossello, E Nuti, ...
Molecules 26 (4), 944, 2021
902021
Vascular ADAM17 as a novel therapeutic target in mediating cardiovascular hypertrophy and perivascular fibrosis induced by angiotensin II
T Takayanagi, SJ Forrester, T Kawai, T Obama, T Tsuji, KJ Elliott, E Nuti, ...
Hypertension 68 (4), 949-955, 2016
842016
N-O-Isopropyl Sulfonamido-Based Hydroxamates: Design, Synthesis and Biological Evaluation of Selective Matrix Metalloproteinase-13 Inhibitors as Potential …
E Nuti, F Casalini, SI Avramova, S Santamaria, G Cercignani, L Marinelli, ...
Journal of medicinal chemistry 52 (15), 4757-4773, 2009
812009
New NO-releasing pharmacodynamic hybrids of losartan and its active metabolite: design, synthesis, and biopharmacological properties
MC Breschi, V Calderone, M Digiacomo, M Macchia, A Martelli, ...
Journal of medicinal chemistry 49 (8), 2628-2639, 2006
802006
Inhibition of metalloproteinases derived from tumours: new insights in the treatment of human glioblastoma
P Gabelloni, E Da Pozzo, S Bendinelli, B Costa, E Nuti, F Casalini, ...
Neuroscience 168 (2), 514-522, 2010
752010
N-O-Isopropyl Sulfonamido-Based Hydroxamates as Matrix Metalloproteinase Inhibitors: Hit Selection and in Vivo Antiangiogenic Activity
E Nuti, AR Cantelmo, C Gallo, A Bruno, B Bassani, C Camodeca, ...
Journal of Medicinal Chemistry 58 (18), 7224-7240, 2015
732015
Design, synthesis, biological evaluation, and NMR studies of a new series of arylsulfones as selective and potent matrix metalloproteinase-12 inhibitors
E Nuti, L Panelli, F Casalini, SI Avramova, E Orlandini, S Santamaria, ...
Journal of medicinal chemistry 52 (20), 6347-6361, 2009
692009
Deficient natural killer cell NKp30‐mediated function and altered NCR3 splice variants in hepatocellular carcinoma
S Mantovani, B Oliviero, A Lombardi, S Varchetta, D Mele, A Sangiovanni, ...
Hepatology 69 (3), 1165-1179, 2019
662019
Crystallization of bi-functional ligand protein complexes
C Antoni, L Vera, L Devel, MP Catalani, B Czarny, E Cassar-Lajeunesse, ...
Journal of Structural Biology 182 (3), 246-254, 2013
632013
Dual inhibitors of matrix metalloproteinases and carbonic anhydrases: iminodiacetyl-based hydroxamate− benzenesulfonamide conjugates
SM Marques, E Nuti, A Rossello, CT Supuran, T Tuccinardi, A Martinelli, ...
Journal of medicinal chemistry 51 (24), 7968-7979, 2008
632008
α-Biphenylsulfonylamino 2-methylpropyl phosphonates: Enantioselective synthesis and selective inhibition of MMPs
A Biasone, P Tortorella, C Campestre, M Agamennone, S Preziuso, ...
Bioorganic & medicinal chemistry 15 (2), 791-799, 2007
622007
Design, synthesis and molecular modeling study of iminodiacetyl monohydroxamic acid derivatives as MMP inhibitors
MA Santos, SM Marques, T Tuccinardi, P Carelli, L Panelli, A Rossello
Bioorganic & medicinal chemistry 14 (22), 7539-7550, 2006
622006
Structural insights on carbonic anhydrase inhibitory action, isoform selectivity, and potency of sulfonamides and coumarins incorporating arylsulfonylureido groups
M Bozdag, M Ferraroni, F Carta, D Vullo, L Lucarini, E Orlandini, ...
Journal of Medicinal Chemistry 57 (21), 9152-9167, 2014
612014
Carbonic anhydrase and matrix metalloproteinase inhibitors. Inhibition of human tumor-associated isozymes IX and cytosolic isozyme I and II with sulfonylated hydroxamates
E Nuti, E Orlandini, S Nencetti, A Rossello, A Innocenti, A Scozzafava, ...
Bioorganic & medicinal chemistry 15 (6), 2298-2311, 2007
612007
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