Chemically defined generation of human cardiomyocytes PW Burridge, E Matsa, P Shukla, ZC Lin, JM Churko, AD Ebert, F Lan, ... Nature methods 11 (8), 855-860, 2014 | 1721 | 2014 |
High-throughput screening of tyrosine kinase inhibitor cardiotoxicity with human induced pluripotent stem cells A Sharma, PW Burridge, WL McKeithan, R Serrano, P Shukla, N Sayed, ... Science translational medicine 9 (377), eaaf2584, 2017 | 377 | 2017 |
Identification of a new modulator of the intercalated disc in a zebrafish model of arrhythmogenic cardiomyopathy A Asimaki, S Kapoor, E Plovie, A Karin Arndt, E Adams, ZZ Liu, CA James, ... Science translational medicine 6 (240), 240ra74-240ra74, 2014 | 285 | 2014 |
Patient-specific and genome-edited induced pluripotent stem cell–derived cardiomyocytes elucidate single-cell phenotype of Brugada syndrome P Liang, K Sallam, H Wu, Y Li, I Itzhaki, P Garg, Y Zhang, V Termglichan, ... Journal of the American College of Cardiology 68 (19), 2086-2096, 2016 | 232 | 2016 |
Overview of high throughput sequencing technologies to elucidate molecular pathways in cardiovascular diseases JM Churko, GL Mantalas, MP Snyder, JC Wu Circulation research 112 (12), 1613-1623, 2013 | 215 | 2013 |
Epigenetic regulation of phosphodiesterases 2A and 3A underlies compromised β-adrenergic signaling in an iPSC model of dilated cardiomyopathy H Wu, J Lee, LG Vincent, Q Wang, M Gu, F Lan, JM Churko, KI Sallam, ... Cell stem cell 17 (1), 89-100, 2015 | 201 | 2015 |
iPSC-derived cardiomyocytes reveal abnormal TGF-β signalling in left ventricular non-compaction cardiomyopathy K Kodo, SG Ong, F Jahanbani, V Termglinchan, K Hirono, ... Nature cell biology 18 (10), 1031-1042, 2016 | 197 | 2016 |
Activation of PDGF pathway links LMNA mutation to dilated cardiomyopathy J Lee, V Termglinchan, S Diecke, I Itzhaki, CK Lam, P Garg, E Lau, ... Nature 572 (7769), 335-340, 2019 | 188 | 2019 |
Defining human cardiac transcription factor hierarchies using integrated single-cell heterogeneity analysis JM Churko, P Garg, B Treutlein, M Venkatasubramanian, H Wu, J Lee, ... Nature communications 9 (1), 4906, 2018 | 187 | 2018 |
Transcriptome profiling of patient-specific human iPSC-cardiomyocytes predicts individual drug safety and efficacy responses in vitro E Matsa, PW Burridge, KH Yu, JH Ahrens, V Termglinchan, H Wu, C Liu, ... Cell stem cell 19 (3), 311-325, 2016 | 182 | 2016 |
Human induced pluripotent stem cell–derived cardiomyocytes as an in vitro model for coxsackievirus B3–induced myocarditis and antiviral drug screening platform A Sharma, C Marceau, R Hamaguchi, PW Burridge, K Rajarajan, ... Circulation research 115 (6), 556-566, 2014 | 172 | 2014 |
Pannexin1 and pannexin3 delivery, cell surface dynamics, and cytoskeletal interactions R Bhalla-Gehi, S Penuela, JM Churko, Q Shao, DW Laird Journal of Biological Chemistry 285 (12), 9147-9160, 2010 | 149 | 2010 |
Loss of pannexin 1 attenuates melanoma progression by reversion to a melanocytic phenotype S Penuela, L Gyenis, A Ablack, JM Churko, AC Berger, DW Litchfield, ... Journal of Biological Chemistry 287 (34), 29184-29193, 2012 | 135 | 2012 |
Implications of pannexin 1 and pannexin 3 for keratinocyte differentiation SJ Celetti, KN Cowan, S Penuela, Q Shao, J Churko, DW Laird Journal of cell science 123 (8), 1363-1372, 2010 | 134 | 2010 |
VEGF-C and aortic cardiomyocytes guide coronary artery stem development HI Chen, A Poduri, H Numi, R Kivela, P Saharinen, AS McKay, B Raftrey, ... The Journal of clinical investigation 124 (11), 4899-4914, 2014 | 128 | 2014 |
Characterization of the molecular mechanisms underlying increased ischemic damage in the aldehyde dehydrogenase 2 genetic polymorphism using a human … AD Ebert, K Kodo, P Liang, H Wu, BC Huber, J Riegler, J Churko, J Lee, ... Science translational medicine 6 (255), 255ra130-255ra130, 2014 | 125 | 2014 |
Generation of human iPSCs from human peripheral blood mononuclear cells using non-integrative Sendai virus in chemically defined conditions JM Churko, PW Burridge, JC Wu Cellular Cardiomyoplasty: Methods and Protocols, 81-88, 2013 | 102 | 2013 |
MMP inhibitors attenuate doxorubicin cardiotoxicity by preventing intracellular and extracellular matrix remodelling BYH Chan, A Roczkowsky, WJ Cho, M Poirier, C Sergi, V Keschrumrus, ... Cardiovascular research 117 (1), 188-200, 2021 | 92 | 2021 |
Novel codon-optimized mini-intronic plasmid for efficient, inexpensive and xeno-free induction of pluripotency S Diecke, J Lu, J Lee, V Termglinchan, NG Kooreman, PW Burridge, ... Scientific reports 5 (1), 8081, 2015 | 86 | 2015 |
Gap junction remodeling in skin repair following wounding and disease JM Churko, DW Laird Physiology 28 (3), 190-198, 2013 | 84 | 2013 |