Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound‐B WE Klunk, H Engler, A Nordberg, Y Wang, G Blomqvist, DP Holt, ... Annals of Neurology: Official Journal of the American Neurological …, 2004 | 5360 | 2004 |
Synthesis and Evaluation of 11C-Labeled 6-Substituted 2-Arylbenzothiazoles as Amyloid Imaging Agents CA Mathis, Y Wang, DP Holt, GF Huang, ML Debnath, WE Klunk Journal of medicinal chemistry 46 (13), 2740-2754, 2003 | 1190 | 2003 |
PET imaging of serotonin 1A receptor binding in depression WC Drevets, E Frank, JC Price, DJ Kupfer, D Holt, PJ Greer, Y Huang, ... Biological psychiatry 46 (10), 1375-1387, 1999 | 904 | 1999 |
Kinetic modeling of amyloid binding in humans using PET imaging and Pittsburgh Compound-B JC Price, WE Klunk, BJ Lopresti, X Lu, JA Hoge, SK Ziolko, DP Holt, ... Journal of Cerebral Blood Flow & Metabolism 25 (11), 1528-1547, 2005 | 791 | 2005 |
Uncharged thioflavin-T derivatives bind to amyloid-beta protein with high affinity and readily enter the brain WE Klunk, Y Wang, G Huang, ML Debnath, DP Holt, CA Mathis Life sciences 69 (13), 1471-1484, 2001 | 593 | 2001 |
A lipophilic thioflavin-T derivative for positron emission tomography (PET) imaging of amyloid in brain CA Mathis, BJ Bacskai, ST Kajdasz, ME McLellan, MP Frosch, BT Hyman, ... Bioorganic & medicinal chemistry letters 12 (3), 295-298, 2002 | 497 | 2002 |
Imaging Aβ plaques in living transgenic mice with multiphoton microscopy and methoxy-X04, a systemically administered Congo red derivative WE Klunk, BJ Bacskai, CA Mathis, ST Kajdasz, ME McLellan, MP Frosch, ... Journal of Neuropathology & Experimental Neurology 61 (9), 797-805, 2002 | 474 | 2002 |
Binding of the positron emission tomography tracer Pittsburgh compound-B reflects the amount of amyloid-β in Alzheimer's disease brain but not in transgenic mouse brain WE Klunk, BJ Lopresti, MD Ikonomovic, IM Lefterov, RP Koldamova, ... Journal of Neuroscience 25 (46), 10598-10606, 2005 | 465 | 2005 |
The binding of 2-(4′-methylaminophenyl) benzothiazole to postmortem brain homogenates is dominated by the amyloid component WE Klunk, Y Wang, G Huang, ML Debnath, DP Holt, L Shao, RL Hamilton, ... Journal of Neuroscience 23 (6), 2086-2092, 2003 | 375 | 2003 |
Biodistribution, tumor detection, and radiation dosimetry of 18F-DCFBC, a low-molecular-weight inhibitor of prostate-specific membrane antigen, in patients with metastatic … SY Cho, KL Gage, RC Mease, S Senthamizhchelvan, DP Holt, ... Journal of Nuclear Medicine 53 (12), 1883-1891, 2012 | 336 | 2012 |
Longitudinal cognitive decline is associated with fibrillar amyloid-beta measured by [11C]PiB SM Resnick, J Sojkova, Y Zhou, Y An, W Ye, DP Holt, RF Dannals, ... Neurology 74 (10), 807-815, 2010 | 315 | 2010 |
18F-DCFBC PET/CT for PSMA-based detection and characterization of primary prostate cancer SP Rowe, KL Gage, SF Faraj, KJ Macura, TC Cornish, ... Journal of Nuclear Medicine 56 (7), 1003-1010, 2015 | 236 | 2015 |
Abnormal sympathetic innervation of viable myocardium and the substrate of ventricular tachycardia after myocardial infarction T Sasano, MR Abraham, KC Chang, H Ashikaga, KJ Mills, DP Holt, ... Journal of the American College of Cardiology 51 (23), 2266-2275, 2008 | 197 | 2008 |
PET measures of amphetamine-induced dopamine release in ventral versus dorsal striatum WC Drevets, JC Price, DJ Kupfer, PE Kinahan, B Lopresti, D Holt, ... Neuropsychopharmacology 21 (6), 694-709, 1999 | 137 | 1999 |
Development of a PET/SPECT agent for amyloid imaging in Alzheimer’s disease Y Wang, WE Klunk, ML Debnath, GF Huang, DP Holt, L Shao, CA Mathis Journal of Molecular Neuroscience 24, 55-62, 2004 | 131 | 2004 |
Gender-specific aging effects on the serotonin 1A receptor CC Meltzer, WC Drevets, JC Price, CA Mathis, B Lopresti, PJ Greer, ... Brain research 895 (1-2), 9-17, 2001 | 128 | 2001 |
11C-JHU75528: a radiotracer for PET imaging of CB1 cannabinoid receptors AG Horti, H Fan, H Kuwabara, J Hilton, HT Ravert, DP Holt, M Alexander, ... Journal of Nuclear Medicine 47 (10), 1689-1696, 2006 | 125 | 2006 |
18F-FPEB, a PET radiopharmaceutical for quantifying metabotropic glutamate 5 receptors: a first-in-human study of radiochemical safety, biokinetics, and radiation dosimetry DF Wong, R Waterhouse, H Kuwabara, J Kim, JR Brašić, W Chamroonrat, ... Journal of nuclear medicine 54 (3), 388-396, 2013 | 123 | 2013 |
Comparison of prostate-specific membrane antigen–based 18F-DCFBC PET/CT to conventional imaging modalities for detection of hormone-naïve and castration-resistant metastatic … SP Rowe, KJ Macura, A Ciarallo, E Mena, A Blackford, R Nadal, ... Journal of Nuclear Medicine 57 (1), 46-53, 2016 | 121 | 2016 |
Using a reference tissue model with spatial constraint to quantify [11C] Pittsburgh compound B PET for early diagnosis of Alzheimer's disease Y Zhou, SM Resnick, W Ye, H Fan, DP Holt, WE Klunk, CA Mathis, ... Neuroimage 36 (2), 298-312, 2007 | 119 | 2007 |