Molecular mechanisms of steroid receptor-mediated actions by synthetic progestins used in HRT and contraception D Africander, N Verhoog, JP Hapgood Steroids 76 (7), 636-652, 2011 | 315 | 2011 |
The injectable-only contraceptive medroxyprogesterone acetate, unlike norethisterone acetate and progesterone, regulates inflammatory genes in endocervical cells via the … Y Govender, C Avenant, NJD Verhoog, RM Ray, NJ Grantham, ... PloS one 9 (5), e96497, 2014 | 84 | 2014 |
Differential regulation of endogenous pro-inflammatory cytokine genes by medroxyprogesterone acetate and norethisterone acetate in cell lines of the female genital tract D Africander, R Louw, N Verhoog, D Noeth, JP Hapgood Contraception 84 (4), 423-435, 2011 | 75 | 2011 |
Glucocorticoid-independent repression of tumor necrosis factor (TNF) α-stimulated interleukin (IL)-6 expression by the glucocorticoid receptor: a potential mechanism for … NJD Verhoog, A Du Toit, C Avenant, JP Hapgood Journal of Biological Chemistry 286 (22), 19297-19310, 2011 | 61 | 2011 |
Disease-and treatment-associated acquired glucocorticoid resistance L Wilkinson, NJD Verhoog, A Louw Endocrine Connections 7 (12), R328-R349, 2018 | 49 | 2018 |
Evaluation of the Phytoestrogenic Activity of Cyclopia genistoides (Honeybush) Methanol Extracts and Relevant Polyphenols NJD Verhoog, E Joubert, A Louw Journal of Agricultural and Food Chemistry 55 (11), 4371-4381, 2007 | 41 | 2007 |
Screening of four Cyclopia (honeybush) species for putative phyto-oestrogenic activity by oestrogen receptor binding assays NJD Verhoog, E Joubert, A Louw South African Journal of Science 103 (1-2), 13-21, 2007 | 29 | 2007 |
Inhibition of corticosteroid-binding globulin gene expression by glucocorticoids involves C/EBPβ N Verhoog, F Allie-Reid, W Vanden Berghe, C Smith, G Haegeman, ... PloS one 9 (10), e110702, 2014 | 28 | 2014 |
Acquired glucocorticoid resistance due to homologous glucocorticoid receptor downregulation: a modern look at an age-old problem LML Spies, NJD Verhoog, A Louw Cells 10 (10), 2529, 2021 | 26 | 2021 |
The association of acute phase proteins in stress and inflammation-induced T2D T Speelman, L Dale, A Louw, NJD Verhoog Cells 11 (14), 2163, 2022 | 20 | 2022 |
Novel role for receptor dimerization in post-translational processing and turnover of the GRα L Wilkinson, N Verhoog, A Louw Scientific reports 8 (1), 14266, 2018 | 20 | 2018 |
Chemoprevention of LA7-Induced Mammary Tumor Growth by SM6Met, a Well-Characterized Cyclopia Extract OR Oyenihi, A Krygsman, N Verhoog, D De Beer, MJ Saayman, ... Frontiers in Pharmacology 9, 650, 2018 | 18 | 2018 |
Point mutation I634A in the glucocorticoid receptor causes embryonic lethality by reduced ligand binding S Timmermans, NJD Verhoog, K Van Looveren, S Dewaele, T Hochepied, ... Journal of Biological Chemistry 298 (2), 2022 | 9 | 2022 |
Combinatorial treatments of tamoxifen and SM6Met, an extract from Cyclopia subternata Vogel, are superior to either treatment alone in MCF-7 cells L Van Dyk, NJD Verhoog, A Louw Frontiers in Pharmacology 13, 1017690, 2022 | 4 | 2022 |
Glucocorticoidindependent Repression of TNFa-stimulated IL-6 Expression by the Glucocorticoid Receptor: A potential Mechanism For the Protection Againsts an Excessive … N Verhoog, A Du Toit, C Avenant, JP Hapgood J Biol Chem 286, 19297-19310, 2011 | 4 | 2011 |
Disease-and treatment-associated acquired glucocorticoid resistance. Endocr Connect.(2018) 7: R328–49. doi: 10.1530 L Wilkinson, NJD Verhoog, A Louw EC-18-0421, 0 | 4 | |
Cyclopia extracts act as selective estrogen receptor subtype downregulators in estrogen receptor positive breast cancer cell lines: Comparison to standard of care … FR Olayoku, NJD Verhoog, A Louw Frontiers in Pharmacology 14, 1122031, 2023 | 3 | 2023 |
The anti-aromatase and anti-estrogenic activity of plant products in the treatment of estrogen receptor-positive breast cancer NJD Verhoog, LML Spies The Journal of Steroid Biochemistry and Molecular Biology, 106581, 2024 | 2 | 2024 |
Acquired glucocorticoid resistance due to homologous glucocorticoid receptor downregulation: a modern look at an age-old problem. Cells 2021, 10: 2529 LL Spies, N Verhoog, A Louw s Note: MDPI stays neutral with regard to jurisdictional claims in published …, 2021 | 2 | 2021 |
Investigation of differential TNFα-induced interleukin-6 gene regulation by synthesis progestins medroxyprogesterone acetate (MPA) and norethindrone acetate (NET-A) in human … NJD Verhoog | 2 | 2010 |