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Roy A Black
Roy A Black
Affiliate Professor of Chemistry, U. of Washington
Dirección de correo verificada de uw.edu
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A metalloproteinase disintegrin that releases tumour-necrosis factor-α from cells
RA Black, CT Rauch, CJ Kozlosky, JJ Peschon, JL Slack, MF Wolfson, ...
Nature 385 (6618), 729-733, 1997
42911997
A metalloproteinase disintegrin that releases tumour-necrosis factor-α from cells
RA Black, CT Rauch, CJ Kozlosky, JJ Peschon, JL Slack, MF Wolfson, ...
Nature 385 (6618), 729-733, 1997
42911997
An essential role for ectodomain shedding in mammalian development
JJ Peschon, JL Slack, P Reddy, KL Stocking, SW Sunnarborg, DC Lee, ...
Science 282 (5392), 1281-1284, 1998
20021998
Molecular cloning of the interleukin-1β converting enzyme
DP Cerretti, CJ Kozlosky, B Mosley, N Nelson, K Van Ness, ...
Science, 97-100, 1992
15971992
A novel proteolytic cleavage involved in Notch signaling: the role of the disintegrin-metalloprotease TACE
C Brou, F Logeat, N Gupta, C Bessia, O LeBail, JR Doedens, A Cumano, ...
Molecular cell 5 (2), 207-216, 2000
15252000
Viral inhibition of inflammation: cowpox virus encodes an inhibitor of the interleukin-1β converting enzyme
CA Ray, RA Black, SR Kronheim, TA Greenstreet, PR Sleath, ...
Cell 69 (4), 597-604, 1992
13431992
Evidence that tumor necrosis factor α converting enzyme is involved in regulated α-secretase cleavage of the Alzheimer amyloid protein precursor
JD Buxbaum, KN Liu, Y Luo, JL Slack, KL Stocking, JJ Peschon, ...
Journal of Biological Chemistry 273 (43), 27765-27767, 1998
13401998
Protection against a lethal dose of endotoxin by an inhibitor of tumour necrosis factor processing
KM Mohler, PR Sleath, JN Fitzner, DP Cerretti, M Alderson, SS Kerwar, ...
Nature 370 (6486), 218-220, 1994
7581994
Functional analysis of the domain structure of tumor necrosis factor-α converting enzyme
P Reddy, JL Slack, R Davis, DP Cerretti, CJ Kozlosky, RA Blanton, ...
Journal of Biological Chemistry 275 (19), 14608-14614, 2000
6832000
ADAMs: focus on the protease domain
RA Black, JM White
Current opinion in cell biology 10 (5), 654-659, 1998
6431998
Tumor necrosis factor-α converting enzyme (TACE) regulates epidermal growth factor receptor ligand availability
SW Sunnarborg, CL Hinkle, M Stevenson, WE Russell, CS Raska, ...
Journal of Biological Chemistry 277 (15), 12838-12845, 2002
5262002
Crystal structure of the catalytic domain of human tumor necrosis factor-α-converting enzyme
K Maskos, C Fernandez-Catalan, R Huber, GP Bourenkov, H Bartunik, ...
Proceedings of the National Academy of Sciences 95 (7), 3408-3412, 1998
5011998
Generation of biologically active interleukin-1 beta by proteolytic cleavage of the inactive precursor.
RA Black, SR Kronheim, M Cantrell, MC Deeley, CJ March, KS Prickett, ...
Journal of Biological Chemistry 263 (19), 9437-9442, 1988
5001988
Tumor necrosis factor α-converting enzyme
RA Black
Handbook of Proteolytic Enzymes, 726-729, 2004
4622004
Rapid and specific conversion of precursor interleukin 1 beta (IL-1 beta) to an active IL-1 species by human mast cell chymase.
H Mizutani, N Schechter, G Lazarus, RA Black, TS Kupper
The Journal of experimental medicine 174 (4), 821-825, 1991
4411991
Activation of interleukin‐1β by a co‐induced protease
RA Black, SR Kronheim, PR Sleath
FEBS letters 247 (2), 386-390, 1989
3871989
Cleavage of interleukin 1 beta (IL-1 beta) precursor to produce active IL-1 beta by a conserved extracellular cysteine protease from Streptococcus pyogenes
V Kapur, MW Majesky, LL Li, RA Black, JM Musser
Proceedings of the National Academy of Sciences 90 (16), 7676-7680, 1993
3361993
A metalloprotease inhibitor blocks shedding of the 80-kD TNF receptor and TNF processing in T lymphocytes.
PD Crowe, BN Walter, KM Mohler, C Otten-Evans, RA Black, CF Ware
The Journal of experimental medicine 181 (3), 1205-1210, 1995
3091995
Metalloproteases regulate T‐cell proliferation and effector function via LAG‐3
N Li, Y Wang, K Forbes, KM Vignali, BS Heale, P Saftig, D Hartmann, ...
The EMBO journal 26 (2), 494-504, 2007
3032007
A metalloprotease inhibitor blocks shedding of the IL-6 receptor and the p60 TNF receptor.
J Müllberg, FH Durie, C Otten-Evans, MR Alderson, S Rose-John, ...
Journal of immunology (Baltimore, Md.: 1950) 155 (11), 5198-5205, 1995
3031995
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