A metalloproteinase disintegrin that releases tumour-necrosis factor-α from cells RA Black, CT Rauch, CJ Kozlosky, JJ Peschon, JL Slack, MF Wolfson, ... Nature 385 (6618), 729-733, 1997 | 4291 | 1997 |
A metalloproteinase disintegrin that releases tumour-necrosis factor-α from cells RA Black, CT Rauch, CJ Kozlosky, JJ Peschon, JL Slack, MF Wolfson, ... Nature 385 (6618), 729-733, 1997 | 4291 | 1997 |
An essential role for ectodomain shedding in mammalian development JJ Peschon, JL Slack, P Reddy, KL Stocking, SW Sunnarborg, DC Lee, ... Science 282 (5392), 1281-1284, 1998 | 2002 | 1998 |
Molecular cloning of the interleukin-1β converting enzyme DP Cerretti, CJ Kozlosky, B Mosley, N Nelson, K Van Ness, ... Science, 97-100, 1992 | 1597 | 1992 |
A novel proteolytic cleavage involved in Notch signaling: the role of the disintegrin-metalloprotease TACE C Brou, F Logeat, N Gupta, C Bessia, O LeBail, JR Doedens, A Cumano, ... Molecular cell 5 (2), 207-216, 2000 | 1525 | 2000 |
Viral inhibition of inflammation: cowpox virus encodes an inhibitor of the interleukin-1β converting enzyme CA Ray, RA Black, SR Kronheim, TA Greenstreet, PR Sleath, ... Cell 69 (4), 597-604, 1992 | 1343 | 1992 |
Evidence that tumor necrosis factor α converting enzyme is involved in regulated α-secretase cleavage of the Alzheimer amyloid protein precursor JD Buxbaum, KN Liu, Y Luo, JL Slack, KL Stocking, JJ Peschon, ... Journal of Biological Chemistry 273 (43), 27765-27767, 1998 | 1340 | 1998 |
Protection against a lethal dose of endotoxin by an inhibitor of tumour necrosis factor processing KM Mohler, PR Sleath, JN Fitzner, DP Cerretti, M Alderson, SS Kerwar, ... Nature 370 (6486), 218-220, 1994 | 758 | 1994 |
Functional analysis of the domain structure of tumor necrosis factor-α converting enzyme P Reddy, JL Slack, R Davis, DP Cerretti, CJ Kozlosky, RA Blanton, ... Journal of Biological Chemistry 275 (19), 14608-14614, 2000 | 683 | 2000 |
ADAMs: focus on the protease domain RA Black, JM White Current opinion in cell biology 10 (5), 654-659, 1998 | 643 | 1998 |
Tumor necrosis factor-α converting enzyme (TACE) regulates epidermal growth factor receptor ligand availability SW Sunnarborg, CL Hinkle, M Stevenson, WE Russell, CS Raska, ... Journal of Biological Chemistry 277 (15), 12838-12845, 2002 | 526 | 2002 |
Crystal structure of the catalytic domain of human tumor necrosis factor-α-converting enzyme K Maskos, C Fernandez-Catalan, R Huber, GP Bourenkov, H Bartunik, ... Proceedings of the National Academy of Sciences 95 (7), 3408-3412, 1998 | 501 | 1998 |
Generation of biologically active interleukin-1 beta by proteolytic cleavage of the inactive precursor. RA Black, SR Kronheim, M Cantrell, MC Deeley, CJ March, KS Prickett, ... Journal of Biological Chemistry 263 (19), 9437-9442, 1988 | 500 | 1988 |
Tumor necrosis factor α-converting enzyme RA Black Handbook of Proteolytic Enzymes, 726-729, 2004 | 462 | 2004 |
Rapid and specific conversion of precursor interleukin 1 beta (IL-1 beta) to an active IL-1 species by human mast cell chymase. H Mizutani, N Schechter, G Lazarus, RA Black, TS Kupper The Journal of experimental medicine 174 (4), 821-825, 1991 | 441 | 1991 |
Activation of interleukin‐1β by a co‐induced protease RA Black, SR Kronheim, PR Sleath FEBS letters 247 (2), 386-390, 1989 | 387 | 1989 |
Cleavage of interleukin 1 beta (IL-1 beta) precursor to produce active IL-1 beta by a conserved extracellular cysteine protease from Streptococcus pyogenes V Kapur, MW Majesky, LL Li, RA Black, JM Musser Proceedings of the National Academy of Sciences 90 (16), 7676-7680, 1993 | 336 | 1993 |
A metalloprotease inhibitor blocks shedding of the 80-kD TNF receptor and TNF processing in T lymphocytes. PD Crowe, BN Walter, KM Mohler, C Otten-Evans, RA Black, CF Ware The Journal of experimental medicine 181 (3), 1205-1210, 1995 | 309 | 1995 |
Metalloproteases regulate T‐cell proliferation and effector function via LAG‐3 N Li, Y Wang, K Forbes, KM Vignali, BS Heale, P Saftig, D Hartmann, ... The EMBO journal 26 (2), 494-504, 2007 | 303 | 2007 |
A metalloprotease inhibitor blocks shedding of the IL-6 receptor and the p60 TNF receptor. J Müllberg, FH Durie, C Otten-Evans, MR Alderson, S Rose-John, ... Journal of immunology (Baltimore, Md.: 1950) 155 (11), 5198-5205, 1995 | 303 | 1995 |