Mitochondrial iron trafficking and the integration of iron metabolism between the mitochondrion and cytosol DR Richardson, DJR Lane, EM Becker, MLH Huang, M Whitnall, ... Proceedings of the National Academy of Sciences 107 (24), 10775-10782, 2010 | 571 | 2010 |
Humans possess two mitochondrial ferredoxins, Fdx1 and Fdx2, with distinct roles in steroidogenesis, heme, and Fe/S cluster biosynthesis AD Sheftel, O Stehling, AJ Pierik, HP Elsässer, U Mühlenhoff, H Webert, ... Proceedings of the National Academy of Sciences 107 (26), 11775-11780, 2010 | 365 | 2010 |
Direct interorganellar transfer of iron from endosome to mitochondrion AD Sheftel, AS Zhang, C Brown, OS Shirihai, P Ponka Blood, The Journal of the American Society of Hematology 110 (1), 125-132, 2007 | 318 | 2007 |
The long history of iron in the Universe and in health and disease AD Sheftel, AB Mason, P Ponka Biochimica et Biophysica Acta (BBA)-General Subjects 1820 (3), 161-187, 2012 | 293 | 2012 |
Iron–sulfur proteins in health and disease A Sheftel, O Stehling, R Lill Trends in Endocrinology & Metabolism 21 (5), 302-314, 2010 | 260 | 2010 |
Human ind1, an iron-sulfur cluster assembly factor for respiratory complex I AD Sheftel, O Stehling, AJ Pierik, DJA Netz, S Kerscher, HP Elsässer, ... Molecular and cellular biology, 2009 | 251 | 2009 |
The human mitochondrial ISCA1, ISCA2, and IBA57 proteins are required for [4Fe-4S] protein maturation AD Sheftel, C Wilbrecht, O Stehling, B Niggemeyer, HP Elsässer, ... Molecular biology of the cell 23 (7), 1157-1166, 2012 | 236 | 2012 |
Overexpression of mitochondrial ferritin causes cytosolic iron depletion and changes cellular iron homeostasis G Nie, AD Sheftel, SF Kim, P Ponka Blood 105 (5), 2161-2167, 2005 | 208 | 2005 |
Human CIA2A-FAM96A and CIA2B-FAM96B integrate iron homeostasis and maturation of different subsets of cytosolic-nuclear iron-sulfur proteins O Stehling, J Mascarenhas, AA Vashisht, AD Sheftel, B Niggemeyer, ... Cell metabolism 18 (2), 187-198, 2013 | 191 | 2013 |
Intracellular kinetics of iron in reticulocytes: evidence for endosome involvement in iron targeting to mitochondria AS Zhang, AD Sheftel, P Ponka Blood 105 (1), 368-375, 2005 | 140 | 2005 |
Erythroid cell mitochondria receive endosomal iron by a “kiss-and-run” mechanism A Hamdi, TM Roshan, TM Kahawita, AB Mason, AD Sheftel, P Ponka Biochimica Et Biophysica Acta (BBA)-Molecular Cell Research 1863 (12), 2859-2867, 2016 | 122 | 2016 |
Prognostic usefulness of insulin-like growth factor-binding protein 7 in heart failure with reduced ejection fraction: a novel biomarker of myocardial diastolic function? PU Gandhi, HK Gaggin, AD Sheftel, AM Belcher, RB Weiner, AL Baggish, ... The American journal of cardiology 114 (10), 1543-1549, 2014 | 87 | 2014 |
Non-heme induction of heme oxygenase-1 does not alter cellular iron metabolism AD Sheftel, SF Kim, P Ponka Journal of Biological Chemistry 282 (14), 10480-10486, 2007 | 81 | 2007 |
Do mammalian cells really need to export and import heme? P Ponka, AD Sheftel, AM English, DS Bohle, D Garcia-Santos Trends in biochemical sciences 42 (5), 395-406, 2017 | 71 | 2017 |
In vivo tumor growth is inhibited by cytosolic iron deprivation caused by the expression of mitochondrial ferritin G Nie, G Chen, AD Sheftel, K Pantopoulos, P Ponka Blood 108 (7), 2428-2434, 2006 | 70 | 2006 |
Mitochondrial iron metabolism and sideroblastic anemia AD Sheftel, DR Richardson, J Prchal, P Ponka Acta haematologica 122 (2-3), 120-133, 2009 | 64 | 2009 |
The power plant of the cell is also a smithy: the emerging role of mitochondria in cellular iron homeostasis AD Sheftel, R Lill Annals of medicine 41 (2), 82-99, 2009 | 63 | 2009 |
Functional consequences of the human DMT1 (SLC11A2) mutation on protein expression and iron uptake M Priwitzerova, G Nie, AD Sheftel, D Pospisilova, V Divoky, P Ponka Blood 106 (12), 3985-3987, 2005 | 58 | 2005 |
Nramp1 equips macrophages for efficient iron recycling S Soe-Lin, AD Sheftel, B Wasyluk, P Ponka Experimental hematology 36 (8), 929-937, 2008 | 57 | 2008 |
The anemia of “haemoglobin-deficit”(hbd/hbd) mice is caused by a defect in transferrin cycling AS Zhang, AD Sheftel, P Ponka Experimental hematology 34 (5), 593-598, 2006 | 50 | 2006 |