Scar1 and the related Wiskott–Aldrich syndrome protein, WASP, regulate the actin cytoskeleton through the Arp2/3 complex LM Machesky, RH Insall Current biology 8 (25), 1347-1356, 1998 | 1211 | 1998 |
Scar, a WASp-related protein, activates nucleation of actin filaments by the Arp2/3 complex LM Machesky, RD Mullins, HN Higgs, DA Kaiser, L Blanchoin, RC May, ... Proceedings of the National Academy of Sciences 96 (7), 3739-3744, 1999 | 1011 | 1999 |
Phagocytosis and the actin cytoskeleton RC May, LM Machesky Journal of cell science 114 (6), 1061-1077, 2001 | 978 | 2001 |
The small GTPases Rho and Rac are required for the establishment of cadherin-dependent cell–cell contacts VMM Braga, LM Machesky, A Hall, NA Hotchin The Journal of cell biology 137 (6), 1421-1431, 1997 | 977 | 1997 |
Purification of a cortical complex containing two unconventional actins from Acanthamoeba by affinity chromatography on profilin-agarose. LM Machesky, SJ Atkinson, C Ampe, J Vandekerckhove, TD Pollard The Journal of cell biology 127 (1), 107-115, 1994 | 709 | 1994 |
Regulation of phospholipase C-γ1 by profilin and tyrosine phosphorylation PJ Goldschmidt-Clermont, JW Kim, LM Machesky, SG Rhee, TD Pollard Science 251 (4998), 1231-1233, 1991 | 680 | 1991 |
Phosphatidylinositol 4, 5-bisphosphate induces actin-based movement of raft-enriched vesicles through WASP-Arp2/3 AL Rozelle, LM Machesky, M Yamamoto, MHE Driessens, RH Insall, ... Current Biology 10 (6), 311-320, 2000 | 632 | 2000 |
The actin-binding protein profilin binds to PIP2 and inhibits its hydrolysis by phospholipase C PJ Goldschmidt-Clermont, LM Machesky, JJ Baldassare, TD Pollard Science 247 (4950), 1575-1578, 1990 | 595 | 1990 |
Role of actin polymerization and adhesion to extracellular matrix in Rac-and Rho-induced cytoskeletal reorganization LM Machesky, A Hall The Journal of cell biology 138 (4), 913-926, 1997 | 505 | 1997 |
Actin dynamics at the leading edge: from simple machinery to complex networks RH Insall, LM Machesky Developmental cell 17 (3), 310-322, 2009 | 502 | 2009 |
Rab27a is required for regulated secretion in cytotoxic T lymphocytes JC Stinchcombe, DC Barral, EH Mules, S Booth, AN Hume, LM Machesky, ... The Journal of cell biology 152 (4), 825-834, 2001 | 478 | 2001 |
The Arp2/3 complex: a multifunctional actin organizer LM Machesky, KL Gould Current opinion in cell biology 11 (1), 117-121, 1999 | 433 | 1999 |
Involvement of the Arp2/3 complex in phagocytosis mediated by FcγR or CR3 RC May, E Caron, A Hall, LM Machesky Nature cell biology 2 (4), 246-248, 2000 | 424 | 2000 |
Configuration of human dendritic cell cytoskeleton by Rho GTPases, the WAS protein, and differentiation S Burns, AJ Thrasher, MP Blundell, L Machesky, GE Jones Blood, The Journal of the American Society of Hematology 98 (4), 1142-1149, 2001 | 412 | 2001 |
Signalling to actin assembly via the WASP (Wiskott-Aldrich syndrome protein)-family proteins and the Arp2/3 complex TH Millard, SJ Sharp, LM Machesky Biochemical Journal 380 (1), 1-17, 2004 | 397 | 2004 |
Rho: a connection between membrane receptor signalling and the cytoskeleton LM Machesky, A Hall Trends in cell biology 6 (8), 304-310, 1996 | 385 | 1996 |
Lamellipodia and filopodia in metastasis and invasion LM Machesky FEBS letters 582 (14), 2102-2111, 2008 | 362 | 2008 |
The actin-bundling protein fascin stabilizes actin in invadopodia and potentiates protrusive invasion A Li, JC Dawson, M Forero-Vargas, HJ Spence, X Yu, I König, K Anderson, ... Current biology 20 (4), 339-345, 2010 | 352 | 2010 |
Regulation of cadherin function by Rho and Rac: modulation by junction maturation and cellular context VMM Braga, A Del Maschio, L Machesky, E Dejana Molecular biology of the cell 10 (1), 9-22, 1999 | 343 | 1999 |
Signaling to actin dynamics LM Machesky, RH Insall The Journal of cell biology 146 (2), 267-272, 1999 | 340 | 1999 |