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Jianhai Du
Jianhai Du
West Virginia University
Dirección de correo verificada de wvumedicine.org - Página principal
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Biochemical adaptations of the retina and retinal pigment epithelium support a metabolic ecosystem in the vertebrate eye
MA Kanow, MM Giarmarco, CSR Jankowski, K Tsantilas, AL Engel, J Du, ...
elife 6, e28899, 2017
3142017
Glucose, lactate, and shuttling of metabolites in vertebrate retinas
JB Hurley, KJ Lindsay, J Du
Journal of neuroscience research 93 (7), 1079-1092, 2015
2332015
Deregulated Myc requires MondoA/Mlx for metabolic reprogramming and tumorigenesis
PA Carroll, D Diolaiti, L McFerrin, H Gu, D Djukovic, J Du, PF Cheng, ...
Cancer cell 27 (2), 271-285, 2015
2102015
Role of autophagy in angiogenesis in aortic endothelial cells
J Du, RJ Teng, T Guan, A Eis, S Kaul, GG Konduri, Y Shi
American Journal of Physiology-Cell Physiology 302 (2), C383-C391, 2012
2062012
The Retinal Pigment Epithelium utilizes Fatty Acids for Ketonegenesis: Implications for Metabolic Coupling with the Outer Retina.
J Adijanto, J Du, C Moffat, EL Seifert, JB Hurley, NJ Philp
Journal of Biological Chemistry, 2014
1602014
Pyruvate Kinase and Aspartate-Glutamate Carrier Distributions Reveal Key Metabolic Links Between Neurons and Glia in Retina
JK Lindsay, J Du, RS Sloat, L Contreras, DJ Linton, JS Turner, M Sadilek, ...
Proceedings of the National Academy of Sciences, 2014
1252014
Noncanonical cAMP pathway and p38 MAPK mediate β2-adrenergic receptor-induced IL-6 production in neonatal mouse cardiac fibroblasts
F Yin, YY Wang, JH Du, C Li, ZZ Lu, C Han, YY Zhang
Journal of molecular and cellular cardiology 40 (3), 384-393, 2006
1162006
Reductive carboxylation is a major metabolic pathway in the retinal pigment epithelium
J Du, A Yanagida, K Knight, AL Engel, AH Vo, C Jankowski, M Sadilek, ...
Proceedings of the National Academy of Sciences 113 (51), 14710-14715, 2016
1102016
Inhibitory crosstalk between ERK and AMPK in the growth and proliferation of cardiac fibroblasts
J Du, T Guan, H Zhang, Y Xia, F Liu, Y Zhang
Biochemical and biophysical research communications 368 (2), 402-407, 2008
1092008
A Novel Protein Kinase A-independent, β-Arrestin-1-dependent Signaling Pathway for p38 Mitogen-activated Protein Kinase Activation by β2-Adrenergic Receptors∗
K Gong, Z Li, M Xu, J Du, Z Lv, Y Zhang
Journal of Biological Chemistry 283 (43), 29028-29036, 2008
1042008
Phototransduction influences metabolic flux and nucleotide metabolism in mouse retina
J Du, A Rountree, WM Cleghorn, L Contreras, KJ Lindsay, M Sadilek, ...
Journal of Biological Chemistry 291 (9), 4698-4710, 2016
982016
Reprogramming metabolism by targeting sirtuin 6 attenuates retinal degeneration
L Zhang, J Du, S Justus, CW Hsu, L Bonet-Ponce, WH Wu, YT Tsai, ...
The Journal of clinical investigation 126 (12), 4659-4673, 2016
942016
Cross talk between NADPH oxidase and autophagy in pulmonary artery endothelial cells with intrauterine persistent pulmonary hypertension
RJ Teng, J Du, S Welak, T Guan, A Eis, Y Shi, GG Konduri
American Journal of Physiology-Lung Cellular and Molecular Physiology 302 (7 …, 2012
942012
Modulating GLUT1 expression in retinal pigment epithelium decreases glucose levels in the retina: impact on photoreceptors and Müller glial cells
A Swarup, IS Samuels, BA Bell, JYS Han, J Du, E Massenzio, ED Abel, ...
American Journal of Physiology-Cell Physiology 316 (1), C121-C133, 2019
932019
Inhibition of mitochondrial pyruvate transport by zaprinast causes massive accumulation of aspartate at the expense of glutamate in the retina
J Du, WM Cleghorn, L Contreras, K Lindsay, AM Rountree, AO Chertov, ...
Journal of Biological Chemistry 288 (50), 36129-36140, 2013
932013
Loss of MPC1 reprograms retinal metabolism to impair visual function
A Grenell, Y Wang, M Yam, A Swarup, TL Dilan, A Hauer, JD Linton, ...
Proceedings of the National Academy of Sciences 116 (9), 3530-3535, 2019
902019
Human retinal pigment epithelial cells prefer proline as a nutrient and transport metabolic intermediates to the retinal side
JR Chao, K Knight, AL Engel, C Jankowski, Y Wang, MA Manson, H Gu, ...
Journal of Biological Chemistry 292 (31), 12895-12905, 2017
902017
Metabolic signature of the aging eye in mice
Y Wang, A Grenell, F Zhong, M Yam, A Hauer, E Gregor, S Zhu, D Lohner, ...
Neurobiology of aging 71, 223-233, 2018
852018
β‐Adrenergic receptors stimulate interleukin‐6 production through Epac‐dependent activation of PKCδ/p38 MAPK signalling in neonatal mouse cardiac fibroblasts
C Chen, J Du, W Feng, Y Song, Z Lu, M Xu, Z Li, Y Zhang
British journal of pharmacology 166 (2), 676-688, 2012
832012
Proline mediates metabolic communication between retinal pigment epithelial cells and the retina
M Yam, AL Engel, Y Wang, S Zhu, A Hauer, R Zhang, D Lohner, J Huang, ...
Journal of Biological Chemistry 294 (26), 10278-10289, 2019
802019
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