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Patrick J. Hanley
Patrick J. Hanley
Chief & Director, Cellular Therapy Program
Dirección de correo verificada de childrensnational.org - Página principal
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Cytotoxic T lymphocyte therapy with donor T cells prevents and treats adenovirus and Epstein-Barr virus infections after haploidentical and matched unrelated stem cell …
AM Leen, A Christin, GD Myers, H Liu, CR Cruz, PJ Hanley, ...
Blood, The Journal of the American Society of Hematology 114 (19), 4283-4292, 2009
3762009
Functionally active virus-specific T cells that target CMV, adenovirus, and EBV can be expanded from naive T-cell populations in cord blood and will target a range of viral …
PJ Hanley, CRY Cruz, B Savoldo, AM Leen, M Stanojevic, M Khalil, ...
Blood, The Journal of the American Society of Hematology 114 (9), 1958-1967, 2009
2932009
Efficient manufacturing of therapeutic mesenchymal stromal cells with the use of the Quantum Cell Expansion System
PJ Hanley, Z Mei, AG Durett, M da Graca Cabreira-Harrison, M Klis, W Li, ...
Cytotherapy 16 (8), 1048-1058, 2014
1732014
Adoptive immunotherapy for primary immunodeficiency disorders with virus-specific T lymphocytes
S Naik, SK Nicholas, CA Martinez, AM Leen, PJ Hanley, SM Gottschalk, ...
Journal of Allergy and Clinical Immunology 137 (5), 1498-1505. e1, 2016
1292016
SARS-CoV-2–specific T cells are rapidly expanded for therapeutic use and target conserved regions of the membrane protein
MD Keller, KM Harris, MA Jensen-Wachspress, VV Kankate, H Lang, ...
Blood, The Journal of the American Society of Hematology 136 (25), 2905-2917, 2020
1282020
Derivation of human T lymphocytes from cord blood and peripheral blood with antiviral and antileukemic specificity from a single culture as protection against infection and …
KP Micklethwaite, B Savoldo, PJ Hanley, AM Leen, GJ Demmler-Harrison, ...
Blood, The Journal of the American Society of Hematology 115 (13), 2695-2703, 2010
1282010
Controlling cytomegalovirus: helping the immune system take the lead
PJ Hanley, CM Bollard
Viruses 6 (6), 2242-2258, 2014
1202014
CMV-specific T cells generated from naive T cells recognize atypical epitopes and may be protective in vivo
PJ Hanley, JJ Melenhorst, S Nikiforow, P Scheinberg, JW Blaney, ...
Science translational medicine 7 (285), 285ra63-285ra63, 2015
1172015
Adverse events following infusion of T cells for adoptive immunotherapy: a 10-year experience
CR Cruz, PJ Hanley, H Liu, V Torrano, YF Lin, JA Arce, S Gottschalk, ...
Cytotherapy 12 (6), 743-749, 2010
1132010
The time is now: moving toward virus-specific T cells after allogeneic hematopoietic stem cell transplantation as the standard of care
F Saglio, PJ Hanley, CM Bollard
Cytotherapy 16 (2), 149-159, 2014
912014
Generation of polyclonal CMV-specific T cells for the adoptive immunotherapy of glioblastoma
A Ghazi, A Ashoori, PJ Hanley, VS Brawley, DR Shaffer, Y Kew, ...
Journal of immunotherapy 35 (2), 159-168, 2012
842012
Manufacturing mesenchymal stromal cells for phase I clinical trials
PJ Hanley, Z Mei, M da Graca Cabreira-Hansen, M Klis, W Li, Y Zhao, ...
Cytotherapy 15 (4), 416-422, 2013
802013
The effects of age and latent cytomegalovirus infection on the redeployment of CD8+ T cell subsets in response to acute exercise in humans
G Spielmann, CM Bollard, AB Bigley, PJ Hanley, JW Blaney, ECP LaVoy, ...
Brain, behavior, and immunity 39, 142-151, 2014
792014
Activation of Wnt signaling arrests effector differentiation in human peripheral and cord blood-derived T lymphocytes
S Muralidharan, PJ Hanley, E Liu, R Chakraborty, C Bollard, E Shpall, ...
The Journal of Immunology 187 (10), 5221-5232, 2011
762011
Immunotherapy of relapsed and refractory solid tumors with ex vivo expanded multi-tumor associated antigen specific cytotoxic T lymphocytes: a phase I study
AB Hont, CR Cruz, R Ulrey, B O’Brien, M Stanojevic, A Datar, S Albihani, ...
Journal of Clinical Oncology 37 (26), 2349-2359, 2019
712019
EBV/LMP-specific T cells maintain remissions of T-and B-cell EBV lymphomas after allogeneic bone marrow transplantation
LP McLaughlin, R Rouce, S Gottschalk, V Torrano, G Carrum, MF Wu, ...
Blood, The Journal of the American Society of Hematology 132 (22), 2351-2361, 2018
712018
Mobilizing immune cells with exercise for cancer immunotherapy
RJ Simpson, AB Bigley, N Agha, PJ Hanley, CM Bollard
Exercise and sport sciences reviews 45 (3), 163-172, 2017
692017
Expansion of T cells targeting multiple antigens of cytomegalovirus, Epstein–Barr virus and adenovirus to provide broad antiviral specificity after stem cell transplantation
PJ Hanley, DR Shaffer, CRY Cruz, S Ku, B Tzou, H Liu, ...
Cytotherapy 13 (8), 976-986, 2011
672011
Virus-specific T-cell therapy to treat BK polyomavirus infection in bone marrow and solid organ transplant recipients
AS Nelson, D Heyenbruch, JD Rubinstein, A Sabulski, S Jodele, ...
Blood advances 4 (22), 5745-5754, 2020
662020
A single bout of dynamic exercise enhances the expansion of MAGE-A4 and PRAME-specific cytotoxic T-cells from healthy adults.
ECP LaVoy, CM Bollard, PJ Hanley, JW Blaney, DP O'Connor, JA Bosch, ...
Exercise immunology review 21, 2015
642015
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