| Parkinsonism-inducing neurotoxin, N-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine: uptake of the metabolite N-methyl-4-phenylpyridine by dopamine neurons explains selective … JA Javitch, RJ D'Amato, SM Strittmatter, SH Snyder Proceedings of the National Academy of Sciences 82 (7), 2173-2177, 1985 | 1602 | 1985 |
| Structure of the human dopamine D3 receptor in complex with a D2/D3 selective antagonist EYT Chien, W Liu, Q Zhao, V Katritch, G Won Han, MA Hanson, L Shi, ... Science 330 (6007), 1091-1095, 2010 | 1358 | 2010 |
| Functional selectivity and classical concepts of quantitative pharmacology JD Urban, WP Clarke, M Von Zastrow, DE Nichols, B Kobilka, H Weinstein, ... Journal of Pharmacology and Experimental Therapeutics 320 (1), 1-13, 2007 | 1330 | 2007 |
| Activation of the β2-adrenergic receptor involves disruption of an ionic lock between the cytoplasmic ends of transmembrane segments 3 and 6 JA Ballesteros, AD Jensen, G Liapakis, SGF Rasmussen, L Shi, U Gether, ... Journal of Biological Chemistry 276 (31), 29171-29177, 2001 | 829 | 2001 |
| Structural mimicry in G protein-coupled receptors: implications of the high-resolution structure of rhodopsin for structure-function analysis of rhodopsin-like receptors JA Ballesteros, L Shi, JA Javitch Molecular Pharmacology 60 (1), 1-19, 2001 | 539 | 2001 |
| β2 adrenergic receptor activation: Modulation of the proline kink in transmembrane 6 by a rotamer toggle switch L Shi, G Liapakis, R Xu, F Guarnieri, JA Ballesteros, JA Javitch Journal of Biological Chemistry 277 (43), 40989-40996, 2002 | 506 | 2002 |
| Building a new conceptual framework for receptor heteromers S Ferré, R Baler, M Bouvier, MG Caron, LA Devi, T Durroux, K Fuxe, ... Nature chemical biology 5 (3), 131-134, 2009 | 484 | 2009 |
| Amphetamine-induced loss of human dopamine transporter activity: an internalization-dependent and cocaine-sensitive mechanism C Saunders, JV Ferrer, L Shi, J Chen, G Merrill, ME Lamb, ... Proceedings of the National Academy of Sciences 97 (12), 6850-6855, 2000 | 480 | 2000 |
| Treatment resistant depression: a multi-scale, systems biology approach H Akil, J Gordon, R Hen, J Javitch, H Mayberg, B McEwen, MJ Meaney, ... Neuroscience & Biobehavioral Reviews 84, 272-288, 2018 | 460 | 2018 |
| The mechanism of a neurotransmitter: sodium symporter—inward release of Na+ and substrate is triggered by substrate in a second binding site L Shi, M Quick, Y Zhao, H Weinstein, JA Javitch Molecular cell 30 (6), 667-677, 2008 | 430 | 2008 |
| The binding sites for cocaine and dopamine in the dopamine transporter overlap T Beuming, J Kniazeff, ML Bergmann, L Shi, L Gracia, K Raniszewska, ... Nature neuroscience 11 (7), 780-789, 2008 | 424 | 2008 |
| Allosteric communication between protomers of dopamine class A GPCR dimers modulates activation Y Han, IS Moreira, E Urizar, H Weinstein, JA Javitch Nature chemical biology 5 (9), 688-695, 2009 | 402 | 2009 |
| The binding site of aminergic G protein–coupled receptors: the transmembrane segments and second extracellular loop L Shi, JA Javitch Annual review of pharmacology and toxicology 42 (1), 437-467, 2002 | 402 | 2002 |
| Time-resolved FRET between GPCR ligands reveals oligomers in native tissues L Albizu, M Cottet, M Kralikova, S Stoev, R Seyer, I Brabet, T Roux, ... Nature chemical biology 6 (8), 587-594, 2010 | 393 | 2010 |
| Discovery of β-arrestin–biased dopamine D2 ligands for probing signal transduction pathways essential for antipsychotic efficacy JA Allen, JM Yost, V Setola, X Chen, MF Sassano, M Chen, S Peterson, ... Proceedings of the National Academy of Sciences 108 (45), 18488-18493, 2011 | 388 | 2011 |
| Amphetamine induces dopamine efflux through a dopamine transporter channel KM Kahlig, F Binda, H Khoshbouei, RD Blakely, DG McMahon, JA Javitch, ... Proceedings of the National Academy of Sciences 102 (9), 3495-3500, 2005 | 384 | 2005 |
| Dopamine D2 receptors form higher order oligomers at physiological expression levels W Guo, E Urizar, M Kralikova, JC Mobarec, L Shi, M Filizola, JA Javitch The EMBO journal 27 (17), 2293-2304, 2008 | 380 | 2008 |
| [3H] mazindol binding associated with neuronal dopamine and norepinephrine uptake sites. JA Javitch, RO Blaustein, SH Snyder Molecular Pharmacology 26 (1), 35-44, 1984 | 369 | 1984 |
| Uptake of MPP (+) by dopamine neurons explains selectivity of parkinsonism-inducing neurotoxin, MPTP JA Javitch Eur. J. Pharmacol. 106, 455-456, 1984 | 365 | 1984 |
| The role of kinetic context in apparent biased agonism at GPCRs C Klein Herenbrink, DA Sykes, P Donthamsetti, M Canals, T Coudrat, ... Nature communications 7 (1), 10842, 2016 | 346 | 2016 |
