Impairment of an endothelial NAD+-H2S signaling network is a reversible cause of vascular aging A Das, GX Huang, MS Bonkowski, A Longchamp, C Li, MB Schultz, ... Cell 173 (1), 74-89. e20, 2018 | 432 | 2018 |
Loss of epigenetic information as a cause of mammalian aging JH Yang, M Hayano, PT Griffin, JA Amorim, MS Bonkowski, ... Cell 186 (2), 305-326. e27, 2023 | 354 | 2023 |
Amino acid restriction triggers angiogenesis via GCN2/ATF4 regulation of VEGF and H2S production A Longchamp, T Mirabella, A Arduini, MR MacArthur, A Das, ... Cell 173 (1), 117-129. e14, 2018 | 297 | 2018 |
SIRT1 activates MAO-A in the brain to mediate anxiety and exploratory drive S Libert, K Pointer, EL Bell, A Das, DE Cohen, JM Asara, K Kapur, ... Cell 147 (7), 1459-1472, 2011 | 281 | 2011 |
Biosynthesis of aromatic polyketides in bacteria A Das, C Khosla Accounts of chemical research 42 (5), 631-639, 2009 | 207 | 2009 |
Acid‐sensing ion channels regulate nucleus pulposus cell inflammation and pyroptosis via the NLRP3 inflammasome in intervertebral disc degeneration K Zhao, R An, Q Xiang, G Li, K Wang, Y Song, Z Liao, S Li, W Hua, X Feng, ... Cell proliferation 54 (1), e12941, 2021 | 153 | 2021 |
A selective inhibitor of ceramide synthase 1 reveals a novel role in fat metabolism N Turner, XY Lim, HD Toop, B Osborne, AE Brandon, EN Taylor, ... Nature communications 9 (1), 3165, 2018 | 128 | 2018 |
Ultrastructure of the liver microcirculation influences hepatic and systemic insulin activity and provides a mechanism for age‐related insulin resistance M Mohamad, SJ Mitchell, LE Wu, MY White, SJ Cordwell, J Mach, ... Aging Cell 15 (4), 706-715, 2016 | 74 | 2016 |
Evidence for Transcriptional Regulation of the Glucose-6-Phosphate Transporter by HIF-1α: Targeting G6PT with Mumbaistatin Analogs in Hypoxic Mesenchymal … S Lord-Dufour, IB Copland, LC Levros Jr, M Post, A Das, C Khosla, ... Stem Cells 27 (3), 489-497, 2009 | 64 | 2009 |
Degenerative cervical myelopathy: insights into its pathobiology and molecular mechanisms J Tu, J Vargas Castillo, A Das, AD Diwan Journal of Clinical Medicine 10 (6), 1214, 2021 | 62 | 2021 |
Gut-disc axis: A cause of intervertebral disc degeneration and low back pain? W Li, K Lai, N Chopra, Z Zheng, A Das, AD Diwan European Spine Journal 31 (4), 917-925, 2022 | 48 | 2022 |
Impairment of an endothelial NAD+-H2S signaling network is a reversible cause of vascular aging A Das, GX Huang, MS Bonkowski, A Longchamp, C Li, MB Schultz, ... Cell 176 (4), 944-945, 2019 | 43 | 2019 |
DNA break-induced epigenetic drift as a cause of mammalian aging M Hayano, JH Yang, MS Bonkowski, JA Amorim, JM Ross, G Coppotelli, ... BioRxiv, 808659, 2019 | 41 | 2019 |
In vivo and in vitro analysis of the hedamycin polyketide synthase A Das, C Khosla Chemistry & biology 16 (11), 1197-1207, 2009 | 36 | 2009 |
Niclosamide reduces glucagon sensitivity via hepatic PKA inhibition in obese mice: Implications for glucose metabolism improvements in type 2 diabetes MKH Chowdhury, N Turner, NL Bentley, A Das, LE Wu, D Richani, ... Scientific reports 7 (1), 40159, 2017 | 32 | 2017 |
Structural and Biochemical Studies of the Hedamycin Type II Polyketide Ketoreductase (HedKR): Molecular Basis of Stereo- and Regiospecificities P Javidpour, A Das, C Khosla, SC Tsai Biochemistry 50 (34), 7426-7439, 2011 | 32 | 2011 |
Impacts of obesity, maternal obesity and nicotinamide mononucleotide supplementation on sperm quality in mice NA Youngson, GM Uddin, A Das, C Martinez, HS Connaughton, S Whiting, ... Reproduction 158 (2), 169-179, 2019 | 27 | 2019 |
Mechanism and engineering of polyketide chain initiation in fredericamycin biosynthesis A Das, PH Szu, JT Fitzgerald, C Khosla Journal of the American Chemical Society 132 (26), 8831-8833, 2010 | 25 | 2010 |
Analysis of the ketosynthase-chain length factor heterodimer from the fredericamycin polyketide synthase PH Szu, S Govindarajan, MJ Meehan, A Das, DD Nguyen, PC Dorrestein, ... Chemistry & biology 18 (8), 1021-1031, 2011 | 23 | 2011 |
The REDD1/TXNIP Complex Accelerates Oxidative Stress‐Induced Apoptosis of Nucleus Pulposus Cells through the Mitochondrial Pathway H Yin, K Wang, A Das, G Li, Y Song, R Luo, JPY Cheung, T Zhang, S Li, ... Oxidative Medicine and Cellular Longevity 2021 (1), 7397516, 2021 | 22 | 2021 |