Daniel Coombs

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MA IrvineBC Centre for Disease ControlDirección de correo verificada de bccdc.ca
Byron GoldsteinLaboratory Fellow, Theoretical Biology and Biophysics Group, Los Alamos National LaboratoryDirección de correo verificada de lanl.gov
Omer DushekProfessor, University of OxfordDirección de correo verificada de path.ox.ac.uk
Raibatak DasFounder and Scientific Director, Quantilogix LLCDirección de correo verificada de cornell.edu
Michael A. GilchristAssociate Professor, University of Tennessee, KnoxvilleDirección de correo verificada de utk.edu
Michael OtterstatterEmmes CanadaDirección de correo verificada de emmes.com
Mark GilbertAssociate Professor, University of British ColumbiaDirección de correo verificada de bccdc.ca
Michael R. GoldMicrobiology and Immunology, University of British ColumbiaDirección de correo verificada de mail.ubc.ca
Rebeca Cardim FalcãoPostdoctoral Researcher at BCCDCDirección de correo verificada de bccdc.ca
Philip Anton van der MerweProfessor of Molecular Immunology, University of OxfordDirección de correo verificada de path.ox.ac.uk
Robert BalshawCentre for Healthcare Innovation, Rady Faculty of Health Sciences, University of ManitobaDirección de correo verificada de umanitoba.ca
Sarafa Adewale IyaniwuraAssociate Research Scientist, Fred Hutchinson Cancer CenterDirección de correo verificada de aims.ac.za
Caroline ColijnSimon Fraser University, Department of MathematicsDirección de correo verificada de sfu.ca
Soren GanttUniversité de MontréalDirección de correo verificada de umontreal.ca
Alan S PerelsonSenior Fellow, Los Alamos National LaboratoryDirección de correo verificada de lanl.gov
Jane A BuxtonProfessor SPPH UBCDirección de correo verificada de ubc.ca
Bernhard KonradUBC VancouverDirección de correo verificada de math.ubc.ca
Naveed Zafar JanjuaBritish Columbia Centre for Disease Control & University of British ColumbiaDirección de correo verificada de bccdc.ca
Mark TyndallProfessor, School of Population and Public Health, UBCDirección de correo verificada de ubc.ca
Guy TanentzapfThe University of British ColumbiaDirección de correo verificada de mail.ubc.ca

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Daniel Coombs

Professor, Mathematics, University of British Columbia

Dirección de correo verificada de math.ubc.ca - Página principal

theoretical immunology virus dynamics cell biophysics epidemiology


Título Ordenar por citas Ordenar por año Ordenar por título	Citado por Citado por	Año
Dependence of T cell antigen recognition on T cell receptor-peptide MHC confinement time M Aleksic, O Dushek, H Zhang, E Shenderov, JL Chen, V Cerundolo, ... Immunity 32 (2), 163-174, 2010	301	2010
Modelling the combined impact of interventions in averting deaths during a synthetic‐opioid overdose epidemic MA Irvine, M Kuo, JA Buxton, R Balshaw, M Otterstatter, L Macdougall, ... Addiction 114 (9), 1602-1613, 2019	219	2019
T cell receptor binding kinetics required for T cell activation depend on the density of cognate ligand on the antigen-presenting cell PA González, LJ Carreño, D Coombs, JE Mora, E Palmieri, B Goldstein, ... Proceedings of the National Academy of Sciences 102 (13), 4824-4829, 2005	184	2005
An age-structured model of HIV infection that allows for variations in the production rate of viral particles and the death rate of productively infected cells PW Nelson, MA Gilchrist, D Coombs, JM Hyman, AS Perelson Mathematical Biosciences & Engineering 1 (2), 267-288, 2004	179	2004
Activated TCRs remain marked for internalization after dissociation from pMHC D Coombs, AM Kalergis, SG Nathenson, C Wofsy, B Goldstein Nature immunology 3 (10), 926-931, 2002	165	2002
Evolution of virulence: interdependence, constraints, and selection using nested models MA Gilchrist, D Coombs Theoretical population biology 69 (2), 145-153, 2006	162	2006
Evaluating the importance of within-and between-host selection pressures on the evolution of chronic pathogens D Coombs, MA Gilchrist, CL Ball Theoretical population biology 72 (4), 576-591, 2007	160	2007
A hidden Markov model for single particle tracks quantifies dynamic interactions between LFA-1 and the actin cytoskeleton R Das, CW Cairo, D Coombs PLoS computational biology 5 (11), e1000556, 2009	159	2009
The influence of transport on the kinetics of binding to surface receptors: application to cells and BIAcore B Goldstein, D Coombs, X He, AR Pineda, C Wofsy Journal of molecular recognition 12 (5), 293-299, 1999	140	1999
Diffusion on a sphere with localized traps: Mean first passage time, eigenvalue asymptotics, and Fekete points D Coombs, R Straube, M Ward SIAM Journal on Applied Mathematics 70 (1), 302-332, 2009	124	2009
Optimizing within-host viral fitness: infected cell lifespan and virion production rate MA Gilchrist, D Coombs, AS Perelson Journal of theoretical biology 229 (2), 281-288, 2004	117	2004
Quantifying the impact of COVID-19 control measures using a Bayesian model of physical distancing SC Anderson, AM Edwards, M Yerlanov, N Mulberry, JE Stockdale, ... PLoS computational biology 16 (12), e1008274, 2020	116	2020
Distribution of take-home opioid antagonist kits during a synthetic opioid epidemic in British Columbia, Canada: a modelling study MA Irvine, JA Buxton, M Otterstatter, R Balshaw, R Gustafson, M Tyndall, ... The Lancet Public Health 3 (5), e218-e225, 2018	110	2018
Equilibrium thermodynamics of cell-cell adhesion mediated by multiple ligand-receptor pairs D Coombs, M Dembo, C Wofsy, B Goldstein Biophysical journal 86 (3), 1408-1423, 2004	108	2004
Toll-like receptor ligands sensitize B-cell receptor signalling by reducing actin-dependent spatial confinement of the receptor SA Freeman, V Jaumouillé, K Choi, BE Hsu, HS Wong, L Abraham, ... Nature communications 6 (1), 6168, 2015	106	2015
A stochastic model of latently infected cell reactivation and viral blip generation in treated HIV patients JM Conway, D Coombs PLoS computational biology 7 (4), e1002033, 2011	106	2011
A role for rebinding in rapid and reliable T cell responses to antigen O Dushek, R Das, D Coombs PLoS computational biology 5 (11), e1000578, 2009	100	2009
Antigen potency and maximal efficacy reveal a mechanism of efficient T cell activation O Dushek, M Aleksic, RJ Wheeler, H Zhang, SP Cordoba, YC Peng, ... Science signaling 4 (176), ra39-ra39, 2011	97	2011
Mechanical force regulates integrin turnover in Drosophila in vivo M Pines, R Das, SJ Ellis, A Morin, S Czerniecki, L Yuan, M Klose, ... Nature cell biology 14 (9), 935-943, 2012	88	2012
Calculations show substantial serial engagement of T cell receptors C Wofsy, D Coombs, B Goldstein Biophysical journal 80 (2), 606-612, 2001	87	2001

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