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Lee Haynes
Lee Haynes
Senior lab manager, Pharmaron Biologics
Dirección de correo verificada de pharmaron-uk.com
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Neuronal Ca2+-sensor proteins: multitalented regulators of neuronal function
RD Burgoyne, DW O'Callaghan, B Hasdemir, LP Haynes, AV Tepikin
Trends in neurosciences 27 (4), 203-209, 2004
2562004
Role of phosphoinositides in STIM1 dynamics and store-operated calcium entry
CM Walsh, M Chvanov, LP Haynes, OH Petersen, AV Tepikin, ...
Biochemical Journal 425 (1), 159-168, 2010
1882010
Interaction of neuronal calcium sensor-1 and ADP-ribosylation factor 1 allows bidirectional control of phosphatidylinositol 4-kinase β and trans-Golgi network-plasma membrane …
LP Haynes, GMH Thomas, RD Burgoyne
Journal of Biological Chemistry 280 (7), 6047-6054, 2005
1562005
Ribosome-free terminals of rough ER allow formation of STIM1 puncta and segregation of STIM1 from IP3 receptors
G Lur, LP Haynes, IA Prior, OV Gerasimenko, S Feske, OH Petersen, ...
Current Biology 19 (19), 1648-1653, 2009
1492009
Calcium-binding protein 1 is an inhibitor of agonist-evoked, inositol 1, 4, 5-trisphosphate-mediated calcium signaling
LP Haynes, AV Tepikin, RD Burgoyne
Journal of Biological Chemistry 279 (1), 547-555, 2004
1462004
The diversity of calcium sensor proteins in the regulation of neuronal function
HV McCue, LP Haynes, RD Burgoyne
Cold Spring Harbor perspectives in biology 2 (8), a004085, 2010
1102010
Understanding the physiological roles of the neuronal calcium sensor proteins
RD Burgoyne, LP Haynes
Molecular brain 5, 1-11, 2012
1062012
Calcium sensors in neuronal function and dysfunction
RD Burgoyne, N Helassa, HV McCue, LP Haynes
Cold Spring Harbor perspectives in biology 11 (5), a035154, 2019
902019
The Rab-binding protein Noc2 is associated with insulin-containing secretory granules and is essential for pancreatic β-cell exocytosis
S Cheviet, T Coppola, LP Haynes, RD Burgoyne, R Regazzi
Molecular Endocrinology 18 (1), 117-126, 2004
902004
Structural and functional deficits in a neuronal calcium sensor-1 mutant identified in a case of autistic spectrum disorder
MTW Handley, LY Lian, LP Haynes, RD Burgoyne
PloS one 5 (5), e10534, 2010
852010
cAMP inhibits migration, ruffling and paxillin accumulation in focal adhesions of pancreatic ductal adenocarcinoma cells: effects of PKA and EPAC
A Burdyga, A Conant, L Haynes, J Zhang, K Jalink, R Sutton, ...
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1833 (12), 2664-2672, 2013
772013
Differential dynamics of Rab3A and Rab27A on secretory granules
MTW Handley, LP Haynes, RD Burgoyne
Journal of cell science 120 (6), 973-984, 2007
752007
InsP3 receptors and Orai channels in pancreatic acinar cells: co-localization and its consequences
G Lur, MW Sherwood, E Ebisui, L Haynes, S Feske, R Sutton, ...
Biochemical Journal 436 (2), 231-239, 2011
702011
Analysis of the interacting partners of the neuronal calcium‐binding proteins L‐CaBP1, hippocalcin, NCS‐1 and neurocalcin δ
LP Haynes, DJ Fitzgerald, B Wareing, DW O'Callaghan, A Morgan, ...
Proteomics 6 (6), 1822-1832, 2006
702006
Sense and specificity in neuronal calcium signalling
RD Burgoyne, LP Haynes
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1853 (9), 1921-1932, 2015
652015
Phospholipase D activity is essential for actin localization and actin-based motility in Dictyostelium
S Zouwail, TR Pettitt, SK Dove, MV Chibalina, DJ Powner, L Haynes, ...
Biochemical Journal 389 (1), 207-214, 2005
652005
A direct inhibitory role for the Rab3-specific effector, Noc2, in Ca2+-regulated exocytosis in neuroendocrine cells
LP Haynes, GJO Evans, A Morgan, RD Burgoyne
Journal of Biological Chemistry 276 (13), 9726-9732, 2001
652001
Specificity, Promiscuity and Localization of ARF Protein Interactions with NCS‐1 and Phosphatidylinositol‐4 Kinase‐IIIβ
LP Haynes, MW Sherwood, NJ Dolman, RD Burgoyne
Traffic 8 (8), 1080-1092, 2007
582007
ATP depletion induces translocation of STIM1 to puncta and formation of STIM1–ORAI1 clusters: translocation and re-translocation of STIM1 does not require ATP
M Chvanov, CM Walsh, LP Haynes, SG Voronina, G Lur, ...
Pflügers Archiv-European Journal of Physiology 457, 505-517, 2008
542008
Identification of phospholipase B from Dictyostelium discoideum reveals a new lipase family present in mammals, flies and nematodes, but not yeast
CP Morgan, R Insall, L Haynes, S Cockcroft
Biochemical Journal 382 (2), 441-449, 2004
512004
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Artículos 1–20