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Dr. Mahima Sharma
Dr. Mahima Sharma
Research Fellow, University of York
Dirección de correo verificada de york.ac.uk - Página principal
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A reductive aminase from Aspergillus oryzae
GA Aleku, SP France, H Man, J Mangas-Sanchez, SL Montgomery, ...
Nature chemistry 9 (10), 961-969, 2017
3602017
Imine reductases (IREDs)
J Mangas-Sanchez, SP France, SL Montgomery, GA Aleku, H Man, ...
Current opinion in chemical biology 37, 19-25, 2017
2502017
NAD (P) H‐dependent dehydrogenases for the asymmetric reductive amination of ketones: Structure, mechanism, evolution and application
M Sharma, J Mangas‐Sanchez, NJ Turner, G Grogan
Advanced Synthesis & Catalysis 359 (12), 2011-2025, 2017
1292017
A mechanism for reductive amination catalyzed by fungal reductive aminases
M Sharma, J Mangas-Sanchez, SP France, GA Aleku, SL Montgomery, ...
ACS Catalysis 8 (12), 11534-11541, 2018
1012018
Biocatalytic Routes to Enantiomerically Enriched Dibenz[c,e]azepines
SP France, GA Aleku, M Sharma, J Mangas‐Sanchez, RM Howard, ...
Angewandte Chemie International Edition 56 (49), 15589-15593, 2017
822017
Asymmetric synthesis of primary amines catalyzed by thermotolerant fungal reductive aminases
J Mangas-Sanchez, M Sharma, SC Cosgrove, JI Ramsden, JR Marshall, ...
Chemical Science 11, 5052-5057, 2020
682020
New imine-reducing enzymes from β-hydroxyacid dehydrogenases by single amino acid substitutions
M Lenz, S Fademrecht, M Sharma, J Pleiss, G Grogan, BM Nestl
Protein Engineering, Design and Selection 31 (4), 109-120, 2018
442018
Substrate Anchoring and Flexibility Reduction in CYP153AM.aq Leads to Highly Improved Efficiency toward Octanoic Acid
LR Rapp, SM Marques, E Zukic, B Rowlinson, M Sharma, G Grogan, ...
ACS Catalysis 11 (5), 3182-3189, 2021
362021
Asymmetric synthesis of primary and secondary β-fluoro-arylamines using reductive aminases from fungi
GJ Grogan, M Sharma, A Cuetos, I Lavandera, V Gotor-Fernández, ...
ChemCatChem, 2020
362020
Inverted binding of non-natural substrates in strictosidine synthase leads to a switch of stereochemical outcome in enzyme-catalyzed pictet–spengler reactions
E Eger, A Simon, M Sharma, S Yang, WB Breukelaar, G Grogan, KN Houk, ...
Journal of the American Chemical Society 142 (2), 792-800, 2020
332020
Sulfoglycolysis: catabolic pathways for metabolism of sulfoquinovose
AJD Snow, L Burchill, M Sharma, GJ Davies, SJ Williams
Chemical Society Reviews, https://doi.org/10.1039/D1CS00846C, 2021
272021
Oxidative desulfurization pathway for complete catabolism of sulfoquinovose by bacteria
M Sharma, JP Lingford, M Petricevic, AJD Snow, Y Zhang, MA Järvå, ...
Proceedings of the National Academy of Sciences 119 (4), e2116022119, 2022
232022
A sulfoglycolytic Entner-Doudoroff pathway in Rhizobium leguminosarum bv. trifolii SRDI565
J Li, R Epa, NE Scott, D Skoneczny, M Sharma, AJD Snow, JP Lingford, ...
Applied and Environmental Microbiology 86 (15), e00750-20, 2020
222020
Dynamic structural changes accompany the production of dihydroxypropanesulfonate by sulfolactaldehyde reductase
M Sharma, P Abayakoon, JP Lingford, R Epa, A John, Y Jin, ...
ACS Catalysis 10 (4), 2826-2836, 2020
222020
Molecular basis of sulfosugar selectivity in sulfoglycolysis
M Sharma, P Abayakoon, R Epa, Y Jin, JP Lingford, T Shimada, ...
ACS Central Science 7 (3), 476-487, 2021
212021
Inverting the stereoselectivity of an NADH-dependent imine reductase variant
P Stockinger, N Borlinghaus, M Sharma, B Aberle, G Grogan, J Pleiss, ...
ChemCatChem, https://doi.org/10.1002/cctc.202101057, 2021
132021
Characterization and structure‐guided engineering of the novel versatile terpene monooxygenase CYP109Q5 from Chondromyces apiculatus DSM436
JM Klenk, P Dubiel, M Sharma, G Grogan, B Hauer
Microbial Biotechnology 12 (2), 377-391, 2019
132019
Identification and characterization of cytochrome P450 1232A24 and 1232F1 from Arthrobacter sp. and their role in the metabolic pathway of papaverine
JM Klenk, MP Fischer, P Dubiel, M Sharma, B Rowlinson, G Grogan, ...
The journal of biochemistry 166 (1), 51-66, 2019
92019
Widespread Family of NAD+-Dependent Sulfoquinovosidases at the Gateway to Sulfoquinovose Catabolism
A Kaur, IB Pickles, M Sharma, N Madeido Soler, NE Scott, SJ Pidot, ...
Journal of the American Chemical Society 145 (51), 28216-28223, 2023
82023
Molecular basis of sulfolactate synthesis by sulfolactaldehyde dehydrogenase from Rhizobium leguminosarum
J Li, M Sharma, R Meek, A Alhifthi, Z Armstrong, NM Soler, M Lee, ...
Chemical Science 14 (41), 11429-11440, 2023
42023
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Artículos 1–20