| Human induced pluripotent stem cell–derived cardiomyocytes recapitulate the predilection of breast cancer patients to doxorubicin-induced cardiotoxicity PW Burridge, YF Li, E Matsa, H Wu, SG Ong, A Sharma, A Holmström, ... Nature medicine 22 (5), 547-556, 2016 | 728 | 2016 |
| High-throughput screening of tyrosine kinase inhibitor cardiotoxicity with human induced pluripotent stem cells A Sharma, PW Burridge, WL McKeithan, R Serrano, P Shukla, N Sayed, ... Science translational medicine 9 (377), eaaf2584, 2017 | 377 | 2017 |
| Screening drug-induced arrhythmia using human induced pluripotent stem cell–derived cardiomyocytes and low-impedance microelectrode arrays EG Navarrete, P Liang, F Lan, V Sanchez-Freire, C Simmons, T Gong, ... Circulation 128 (11_suppl_1), S3-S13, 2013 | 354 | 2013 |
| A tension-based model distinguishes hypertrophic versus dilated cardiomyopathy J Davis, LC Davis, RN Correll, CA Makarewich, JA Schwanekamp, ... Cell 165 (5), 1147-1159, 2016 | 260 | 2016 |
| Patient-specific and genome-edited induced pluripotent stem cell–derived cardiomyocytes elucidate single-cell phenotype of Brugada syndrome P Liang, K Sallam, H Wu, Y Li, I Itzhaki, P Garg, Y Zhang, V Termglichan, ... Journal of the American College of Cardiology 68 (19), 2086-2096, 2016 | 232 | 2016 |
| Fast two-photon imaging of subcellular voltage dynamics in neuronal tissue with genetically encoded indicators S Chamberland, HH Yang, MM Pan, SW Evans, S Guan, M Chavarha, ... elife 6, e25690, 2017 | 224 | 2017 |
| Epigenetic regulation of phosphodiesterases 2A and 3A underlies compromised β-adrenergic signaling in an iPSC model of dilated cardiomyopathy H Wu, J Lee, LG Vincent, Q Wang, M Gu, F Lan, JM Churko, KI Sallam, ... Cell stem cell 17 (1), 89-100, 2015 | 201 | 2015 |
| Activation of PDGF pathway links LMNA mutation to dilated cardiomyopathy J Lee, V Termglinchan, S Diecke, I Itzhaki, CK Lam, P Garg, E Lau, ... Nature 572 (7769), 335-340, 2019 | 188 | 2019 |
| Defining human cardiac transcription factor hierarchies using integrated single-cell heterogeneity analysis JM Churko, P Garg, B Treutlein, M Venkatasubramanian, H Wu, J Lee, ... Nature communications 9 (1), 4906, 2018 | 187 | 2018 |
| Genome editing of isogenic human induced pluripotent stem cells recapitulates long QT phenotype for drug testing Y Wang, P Liang, F Lan, H Wu, L Lisowski, M Gu, S Hu, MA Kay, ... Journal of the American College of Cardiology 64 (5), 451-459, 2014 | 186 | 2014 |
| Transcriptome profiling of patient-specific human iPSC-cardiomyocytes predicts individual drug safety and efficacy responses in vitro E Matsa, PW Burridge, KH Yu, JH Ahrens, V Termglinchan, H Wu, C Liu, ... Cell stem cell 19 (3), 311-325, 2016 | 182 | 2016 |
| Human induced pluripotent stem cell–derived cardiomyocytes as an in vitro model for coxsackievirus B3–induced myocarditis and antiviral drug screening platform A Sharma, C Marceau, R Hamaguchi, PW Burridge, K Rajarajan, ... Circulation research 115 (6), 556-566, 2014 | 172 | 2014 |
| Wnt activation and reduced cell-cell contact synergistically induce massive expansion of functional human iPSC-derived cardiomyocytes JW Buikema, S Lee, WR Goodyer, RG Maas, O Chirikian, G Li, Y Miao, ... Cell stem cell 27 (1), 50-63. e5, 2020 | 167 | 2020 |
| Generation of quiescent cardiac fibroblasts from human induced pluripotent stem cells for in vitro modeling of cardiac fibrosis H Zhang, L Tian, M Shen, C Tu, H Wu, M Gu, DT Paik, JC Wu Circulation research 125 (5), 552-566, 2019 | 142 | 2019 |
| Human AML-iPSCs reacquire leukemic properties after differentiation and model clonal variation of disease MP Chao, AJ Gentles, S Chatterjee, F Lan, A Reinisch, MR Corces, ... Cell stem cell 20 (3), 329-344. e7, 2017 | 140 | 2017 |
| Determining the pathogenicity of a genomic variant of uncertain significance using CRISPR/Cas9 and human-induced pluripotent stem cells N Ma, JZ Zhang, I Itzhaki, SL Zhang, H Chen, F Haddad, T Kitani, ... Circulation 138 (23), 2666-2681, 2018 | 138 | 2018 |
| In vivo suppression of microRNA-24 prevents the transition toward decompensated hypertrophy in aortic-constricted mice RC Li, J Tao, YB Guo, HD Wu, RF Liu, Y Bai, ZZ Lv, GZ Luo, LL Li, ... Circulation research 112 (4), 601-605, 2013 | 131 | 2013 |
| A computational model of induced pluripotent stem‐cell derived cardiomyocytes incorporating experimental variability from multiple data sources DC Kernik, S Morotti, HD Wu, P Garg, HJ Duff, J Kurokawa, J Jalife, ... The Journal of physiology 597 (17), 4533-4564, 2019 | 126 | 2019 |
| A human iPSC double-reporter system enables purification of cardiac lineage subpopulations with distinct function and drug response profiles JZ Zhang, V Termglinchan, NY Shao, I Itzhaki, C Liu, N Ma, L Tian, ... Cell Stem Cell 24 (5), 802-811. e5, 2019 | 125 | 2019 |
| Characterization of the molecular mechanisms underlying increased ischemic damage in the aldehyde dehydrogenase 2 genetic polymorphism using a human … AD Ebert, K Kodo, P Liang, H Wu, BC Huber, J Riegler, J Churko, J Lee, ... Science translational medicine 6 (255), 255ra130-255ra130, 2014 | 125 | 2014 |
Arun SharmaAssistant Professor, Cedars-Sinai Medical CenterDirección de correo verificada de cshs.org