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Michael Ashton
Michael Ashton
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Neural correlates of the DMT experience assessed with multivariate EEG
C Timmermann, L Roseman, M Schartner, R Milliere, LTJ Williams, ...
Scientific reports 9 (1), 16324, 2019
2882019
Identification of the human cytochrome P450 enzymes involved in the in vitro metabolism of artemisinin
Svensson, Ashton
British journal of clinical pharmacology 48 (4), 528-535, 1999
2421999
High prevalence of the CYP2B6 516G→T(*6) variant and effect on the population pharmacokinetics of efavirenz in HIV/AIDS outpatients in Zimbabwe
C Nyakutira, D Röshammar, E Chigutsa, P Chonzi, M Ashton, C Nhachi, ...
European journal of clinical pharmacology 64, 357-365, 2008
2412008
Artemisinin pharmacokinetics is time-dependent during repeated oral administration in healthy male adults
M Ashton, TN Hai, ND Sy, DX Huong, N Van Huong, NT Nieu
Drug Metabolism and Disposition 26 (1), 25-27, 1998
1671998
Multiple dose pharmacokinetics of oral artemisinin and comparison of its efficacy with that of oral artesunate in falciparum malaria patients
MH Alin, M Ashton, CM Kihamia, GJB Mtey, A Björkman
Transactions of the Royal Society of Tropical Medicine and Hygiene 90 (1), 61-65, 1996
1571996
Population pharmacokinetics of piperaquine after two different treatment regimens with dihydroartemisinin-piperaquine in patients with Plasmodium falciparum malaria in Thailand
J Tarning, EA Ashley, N Lindegardh, K Stepniewska, L Phaiphun, ...
Antimicrobial agents and chemotherapy 52 (3), 1052-1061, 2008
1532008
Artemisinin kinetics and dynamics during oral and rectal treatment of uncomplicated malaria
M Ashton, ND Sy, N Van Huong, T Gordi, TN Hai, DX Huong, NT Niêu, ...
Clinical Pharmacology & Therapeutics 63 (4), 482-493, 1998
1531998
Artemisinin autoinduction is caused by involvement of cytochrome P450 2B6 but not 2C9
USH Simonsson, B Jansson, TN Hai, DX Huong, G Tybring, M Ashton
Clinical Pharmacology & Therapeutics 74 (1), 32-43, 2003
1272003
A semiphysiological pharmacokinetic model for artemisinin in healthy subjects incorporating autoinduction of metabolism and saturable first‐pass hepatic extraction
T Gordi, R Xie, NV Huong, DX Huong, MO Karlsson, M Ashton
British journal of clinical pharmacology 59 (2), 189-198, 2005
1262005
Artemisinin induces omeprazole metabolism in human beings
USH Svensson, M Ashton, TN Hai, L Bertilsson, DX Huong, N Van Huong, ...
Clinical Pharmacology & Therapeutics 64 (2), 160-167, 1998
1061998
Artemisinin pharmacokinetics and efficacy in uncomplicated-malaria patients treated with two different dosage regimens
T Gordi, DX Huong, TN Hai, NT Nieu, M Ashton
Antimicrobial agents and chemotherapy 46 (4), 1026-1031, 2002
962002
Pitfalls in estimating piperaquine elimination
J Tarning, N Lindegårdh, A Annerberg, T Singtoroj, NPJ Day, M Ashton, ...
Antimicrobial agents and chemotherapy 49 (12), 5127-5128, 2005
952005
Artemisinin antimalarials moderately affect cytochrome P450 enzyme activity in healthy subjects
S Asimus, D Elsherbiny, TN Hai, B Jansson, NV Huong, MG Petzold, ...
Fundamental & clinical pharmacology 21 (3), 307-316, 2007
922007
A new approach to evaluate regression models during validation of bioanalytical assays
T Singtoroj, J Tarning, A Annerberg, M Ashton, Y Bergqvist, NJ White, ...
Journal of pharmaceutical and biomedical analysis 41 (1), 219-227, 2006
882006
Artemisinin pharmacokinetics in healthy adults after 250, 500 and 1000 mg single oral doses
M Ashton, T Gordi, TN Hai, N Van Huong, ND Sy, NT Nieu, DX Huong, ...
Biopharmaceutics & drug disposition 19 (4), 245-250, 1998
851998
Clinical efficacy and pharmacokinetics of artemisinin monotherapy and in combination with mefloquine in patients with falciparum malaria
M Hassan Alin, M Ashton, CM Kihamia, GJB Mtey, A Björkman
British journal of clinical pharmacology 41 (6), 587-592, 1996
851996
High in situ rat intestinal permeability of artemisinin unaffected by multiple dosing and with no evidence of P-glycoprotein involvement
USH Svensson, R Sandström, Ö Carlborg, H Lennernäs, M Ashton
Drug metabolism and disposition 27 (2), 227-232, 1999
841999
Safety and tolerability of high-dose angiotensin receptor blocker therapy in patients with chronic kidney disease: a pilot study
AJ Weinberg, DH Zappe, M Ashton, MS Weinberg
American journal of nephrology 24 (3), 340-345, 2004
792004
Pharmacogenomics of CYP2A6, CYP2B6, CYP2C19, CYP2D6, CYP3A4, CYP3A5 and MDR1 in Vietnam
MI Veiga, S Asimus, PE Ferreira, JP Martins, I Cavaco, V Ribeiro, TN Hai, ...
European journal of clinical pharmacology 65, 355-363, 2009
732009
Population pharmacokinetic and pharmacodynamic modelling of artemisinin and mefloquine enantiomers in patients with falciparum malaria
US Svensson, M Alin, MO Karlsson, Y Bergqvist, M Ashton
European journal of clinical pharmacology 58, 339-351, 2002
662002
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Artículos 1–20