| Comparative tropism, replication kinetics, and cell damage profiling of SARS-CoV-2 and SARS-CoV with implications for clinical manifestations, transmissibility, and laboratory … H Chu, JFW Chan, TTT Yuen, H Shuai, S Yuan, Y Wang, B Hu, CCY Yip, ... The Lancet Microbe 1 (1), e14-e23, 2020 | 886 | 2020 |
| Treatment with lopinavir/ritonavir or interferon-β1b improves outcome of MERS-CoV infection in a nonhuman primate model of common marmoset JFW Chan, Y Yao, ML Yeung, W Deng, L Bao, L Jia, F Li, C Xiao, H Gao, ... The Journal of infectious diseases 212 (12), 1904-1913, 2015 | 804 | 2015 |
| Comparative replication and immune activation profiles of SARS-CoV-2 and SARS-CoV in human lungs: an ex vivo study with implications for the pathogenesis of COVID-19 H Chu, JFW Chan, Y Wang, TTT Yuen, Y Chai, Y Hou, H Shuai, D Yang, ... Clinical Infectious Diseases 71 (6), 1400-1409, 2020 | 754 | 2020 |
| Attenuated replication and pathogenicity of SARS-CoV-2 B. 1.1. 529 Omicron H Shuai, JFW Chan, B Hu, Y Chai, TTT Yuen, F Yin, X Huang, C Yoon, ... Nature 603 (7902), 693-699, 2022 | 592 | 2022 |
| Infection of bat and human intestinal organoids by SARS-CoV-2 J Zhou, C Li, X Liu, MC Chiu, X Zhao, D Wang, Y Wei, A Lee, AJ Zhang, ... Nature medicine 26 (7), 1077-1083, 2020 | 572 | 2020 |
| Active replication of Middle East respiratory syndrome coronavirus and aberrant induction of inflammatory cytokines and chemokines in human macrophages: implications for … J Zhou, H Chu, C Li, BHY Wong, ZS Cheng, VKM Poon, T Sun, CCY Lau, ... The Journal of infectious diseases 209 (9), 1331-1342, 2014 | 496 | 2014 |
| Middle East respiratory syndrome coronavirus efficiently infects human primary T lymphocytes and activates the extrinsic and intrinsic apoptosis pathways H Chu, J Zhou, BHY Wong, C Li, JFW Chan, ZS Cheng, D Yang, D Wang, ... The Journal of infectious diseases 213 (6), 904-914, 2016 | 493 | 2016 |
| Human intestinal tract serves as an alternative infection route for Middle East respiratory syndrome coronavirus J Zhou, C Li, G Zhao, H Chu, D Wang, HHN Yan, VKM Poon, L Wen, ... Science advances 3 (11), eaao4966, 2017 | 442 | 2017 |
| Differentiated human airway organoids to assess infectivity of emerging influenza virus J Zhou, C Li, N Sachs, MC Chiu, BHY Wong, H Chu, VKM Poon, D Wang, ... Proceedings of the National Academy of Sciences 115 (26), 6822-6827, 2018 | 269 | 2018 |
| SREBP-dependent lipidomic reprogramming as a broad-spectrum antiviral target S Yuan, H Chu, JFW Chan, ZW Ye, L Wen, B Yan, PM Lai, KM Tee, ... Nature communications 10 (1), 120, 2019 | 244 | 2019 |
| Productive replication of Middle East respiratory syndrome coronavirus in monocyte-derived dendritic cells modulates innate immune response H Chu, J Zhou, BHY Wong, C Li, ZS Cheng, X Lin, VKM Poon, T Sun, ... Virology 454, 197-205, 2014 | 217 | 2014 |
| The adamantane-derived bananins are potent inhibitors of the helicase activities and replication of SARS coronavirus JA Tanner, BJ Zheng, J Zhou, RM Watt, JQ Jiang, KL Wong, YP Lin, LY Lu, ... Chemistry & biology 12 (3), 303-311, 2005 | 206 | 2005 |
| Attenuated interferon and proinflammatory response in SARS-CoV-2–infected human dendritic cells is associated with viral antagonism of STAT1 phosphorylation D Yang, H Chu, Y Hou, Y Chai, H Shuai, ACY Lee, X Zhang, Y Wang, ... The Journal of infectious diseases 222 (5), 734-745, 2020 | 200 | 2020 |
| Middle East respiratory syndrome coronavirus and bat coronavirus HKU9 both can utilize GRP78 for attachment onto host cells H Chu, CM Chan, X Zhang, Y Wang, S Yuan, J Zhou, RKH Au-Yeung, ... Journal of Biological Chemistry 293 (30), 11709-11726, 2018 | 190 | 2018 |
| MERS coronavirus induces apoptosis in kidney and lung by upregulating Smad7 and FGF2 ML Yeung, Y Yao, L Jia, JFW Chan, KH Chan, KF Cheung, H Chen, ... Nature microbiology 1 (3), 1-8, 2016 | 190 | 2016 |
| Identification of TMPRSS2 as a Susceptibility Gene for Severe 2009 Pandemic A(H1N1) Influenza and A(H7N9) Influenza Z Cheng, J Zhou, KKW To, H Chu, C Li, D Wang, D Yang, S Zheng, K Hao, ... The Journal of infectious diseases 212 (8), 1214-1221, 2015 | 187 | 2015 |
| A novel peptide with potent and broad-spectrum antiviral activities against multiple respiratory viruses H Zhao, J Zhou, K Zhang, H Chu, D Liu, VKM Poon, CCS Chan, ... Scientific reports 6 (1), 22008, 2016 | 178 | 2016 |
| SARS-related virus predating SARS outbreak, Hong Kong BJ Zheng, Y Guan, KH Wong, J Zhou, KL Wong, BWY Young, LW Lu, ... Emerging infectious diseases 10 (2), 176, 2004 | 161 | 2004 |
| Host and viral determinants for efficient SARS-CoV-2 infection of the human lung H Chu, B Hu, X Huang, Y Chai, D Zhou, Y Wang, H Shuai, D Yang, Y Hou, ... Nature communications 12 (1), 134, 2021 | 144 | 2021 |
| Selective functional deficit in dendritic cell–T cell interaction is a crucial mechanism in chronic hepatitis B virus infection BJ Zheng, J Zhou, D Qu, KL Siu, TW Lam, HY Lo, SS Lee, YM Wen Journal of viral hepatitis 11 (3), 217-224, 2004 | 140 | 2004 |