| A potent mechanism-inspired O-GlcNAcase inhibitor that blocks phosphorylation of tau in vivo SA Yuzwa, MS Macauley, JE Heinonen, X Shan, RJ Dennis, Y He, ... Nature chemical biology 4 (8), 483-490, 2008 | 811 | 2008 |
| Perturbation of Indole-3-Butyric Acid Homeostasis by the UDP-Glucosyltransferase UGT74E2 Modulates Arabidopsis Architecture and Water Stress Tolerance VB Tognetti, O Van Aken, K Morreel, K Vandenbroucke, B Van De Cotte, ... The Plant Cell 22 (8), 2660-2679, 2010 | 492 | 2010 |
| Structure and mechanism of a bacterial β-glucosaminidase having O-GlcNAcase activity RJ Dennis, EJ Taylor, MS Macauley, KA Stubbs, JP Turkenburg, SJ Hart, ... Nature structural & molecular biology 13 (4), 365-371, 2006 | 246 | 2006 |
| Analysis of PUGNAc and NAG-thiazoline as Transition State Analogues for Human O-GlcNAcase: Mechanistic and Structural Insights into Inhibitor Selectivity and … GE Whitworth, MS Macauley, KA Stubbs, RJ Dennis, EJ Taylor, GJ Davies, ... Journal of the American Chemical Society 129 (3), 635-644, 2007 | 199 | 2007 |
| Carrageenan catabolism is encoded by a complex regulon in marine heterotrophic bacteria E Ficko-Blean, A Préchoux, F Thomas, T Rochat, R Larocque, Y Zhu, ... Nature communications 8 (1), 1685, 2017 | 158 | 2017 |
| Identification of Asp174 and Asp175 as the Key Catalytic Residues of Human O-GlcNAcase by Functional Analysis of Site-Directed Mutants N Çetinbaş, MS Macauley, KA Stubbs, R Drapala, DJ Vocadlo Biochemistry 45 (11), 3835-3844, 2006 | 141 | 2006 |
| Small molecule inhibitors of a glycoside hydrolase attenuate inducible AmpC-mediated β-lactam resistance KA Stubbs, M Balcewich, BL Mark, DJ Vocadlo Journal of Biological Chemistry 282 (29), 21382-21391, 2007 | 140 | 2007 |
| Structure of a lipid A phosphoethanolamine transferase suggests how conformational changes govern substrate binding A Anandan, GL Evans, K Condic-Jurkic, ML O’Mara, CM John, NJ Phillips, ... Proceedings of the National Academy of Sciences 114 (9), 2218-2223, 2017 | 138 | 2017 |
| The structure of the neisserial lipooligosaccharide phosphoethanolamine transferase A (LptA) required for resistance to polymyxin C Wanty, A Anandan, S Piek, J Walshe, J Ganguly, RW Carlson, ... Journal of molecular biology 425 (18), 3389-3402, 2013 | 124 | 2013 |
| Structural and mechanistic insight into the basis of mucopolysaccharidosis IIIB E Ficko-Blean, KA Stubbs, O Nemirovsky, DJ Vocadlo, AB Boraston Proceedings of the National Academy of Sciences 105 (18), 6560-6565, 2008 | 119 | 2008 |
| Molecular insight into evolution of symbiosis between breast-fed infants and a member of the human gut microbiome Bifidobacterium longum C Yamada, A Gotoh, M Sakanaka, M Hattie, KA Stubbs, ... Cell chemical biology 24 (4), 515-524. e5, 2017 | 115 | 2017 |
| Synthesis and Use of Mechanism-Based Protein-Profiling Probes for Retaining β-d-Glucosaminidases Facilitate Identification of Pseudomonas aeruginosa NagZ KA Stubbs, A Scaffidi, AW Debowski, BL Mark, RV Stick, DJ Vocadlo Journal of the American Chemical Society 130 (1), 327-335, 2008 | 115 | 2008 |
| Optimising a vortex fluidic device for controlling chemical reactivity and selectivity L Yasmin, X Chen, KA Stubbs, CL Raston Scientific reports 3 (1), 2282, 2013 | 106 | 2013 |
| O-GlcNAcase Catalyzes Cleavage of Thioglycosides without General Acid Catalysis MS Macauley, KA Stubbs, DJ Vocadlo Journal of the American Chemical Society 127 (49), 17202-17203, 2005 | 105 | 2005 |
| Lipopolysaccharide Structure and Biosynthesis in Helicobacter pylori H Li, T Liao, AW Debowski, H Tang, HO Nilsson, KA Stubbs, BJ Marshall, ... Helicobacter 21 (6), 445-461, 2016 | 103 | 2016 |
| Inhibition of O-GlcNAcase using a potent and cell-permeable inhibitor does not induce insulin resistance in 3T3-L1 adipocytes MS Macauley, Y He, TM Gloster, KA Stubbs, GJ Davies, DJ Vocadlo Chemistry & biology 17 (9), 937-948, 2010 | 101 | 2010 |
| Visualizing the reaction coordinate of an O-GlcNAc hydrolase Y He, MS Macauley, KA Stubbs, DJ Vocadlo, GJ Davies Journal of the American Chemical Society 132 (6), 1807-1809, 2010 | 95 | 2010 |
| Vortex fluidic chemical transformations J Britton, KA Stubbs, GA Weiss, CL Raston Chemistry–A European Journal 23 (54), 13270-13278, 2017 | 90 | 2017 |
| Helicobacter pylori gene silencing in vivo demonstrates urease is essential for chronic infection AW Debowski, SM Walton, EG Chua, ACY Tay, T Liao, B Lamichhane, ... PLoS pathogens 13 (6), e1006464, 2017 | 87 | 2017 |
| A divergent synthesis of 2-acyl derivatives of PUGNAc yields selective inhibitors of O-GlcNAcase KA Stubbs, N Zhang, DJ Vocadlo Organic & Biomolecular Chemistry 4 (5), 839-845, 2006 | 86 | 2006 |
