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Craig Mermel
Craig Mermel
President and Chief Product Officer, Precision Neuroscience
Dirección de correo verificada de precisionneuro.io
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Comprehensive genomic characterization defines human glioblastoma genes and core pathways
Cancer Genome Atlas Research Network Tissue source sites: Duke University ...
Nature 455 (7216), 1061-1068, 2008
75892008
Integrated genomic analyses of ovarian carcinoma
Cancer Genome Atlas Research Network
Nature 474 (7353), 609, 2011
70922011
Mutational heterogeneity in cancer and the search for new cancer-associated genes
MS Lawrence, P Stojanov, P Polak, GV Kryukov, K Cibulskis, ...
Nature 499 (7457), 214-218, 2013
60052013
Age-related clonal hematopoiesis associated with adverse outcomes
S Jaiswal, P Fontanillas, J Flannick, A Manning, PV Grauman, BG Mar, ...
New England Journal of Medicine 371 (26), 2488-2498, 2014
46342014
The landscape of somatic copy-number alteration across human cancers
R Beroukhim, CH Mermel, D Porter, G Wei, S Raychaudhuri, J Donovan, ...
Nature 463 (7283), 899-905, 2010
44222010
Discovery and saturation analysis of cancer genes across 21 tumour types
MS Lawrence, P Stojanov, CH Mermel, JT Robinson, LA Garraway, ...
Nature 505 (7484), 495-501, 2014
33452014
Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1
DA Barbie, P Tamayo, JS Boehm, SY Kim, SE Moody, IF Dunn, ...
Nature 462 (7269), 108-112, 2009
33302009
GISTIC2. 0 facilitates sensitive and confident localization of the targets of focal somatic copy-number alteration in human cancers
CH Mermel, SE Schumacher, B Hill, ML Meyerson, R Beroukhim, G Getz
Genome biology 12, 1-14, 2011
31422011
Pan-cancer patterns of somatic copy number alteration
TI Zack, SE Schumacher, SL Carter, AD Cherniack, G Saksena, B Tabak, ...
Nature genetics 45 (10), 1134-1140, 2013
20002013
EML4-ALK Fusion Gene and Efficacy of an ALK Kinase Inhibitor in Lung Cancer
JP Koivunen, C Mermel, K Zejnullahu, C Murphy, E Lifshits, AJ Holmes, ...
Clinical cancer research 14 (13), 4275-4283, 2008
12582008
SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas
AJ Bass, H Watanabe, CH Mermel, S Yu, S Perner, RG Verhaak, SY Kim, ...
Nature genetics 41 (11), 1238-1242, 2009
10882009
Lin28 promotes transformation and is associated with advanced human malignancies
SR Viswanathan, JT Powers, W Einhorn, Y Hoshida, TL Ng, S Toffanin, ...
Nature genetics 41 (7), 843-848, 2009
9652009
CDK8 is a colorectal cancer oncogene that regulates β-catenin activity
R Firestein, AJ Bass, SY Kim, IF Dunn, SJ Silver, I Guney, E Freed, ...
Nature 455 (7212), 547-551, 2008
8162008
Subtype-specific genomic alterations define new targets for soft-tissue sarcoma therapy
J Barretina, BS Taylor, S Banerji, AH Ramos, M Lagos-Quintana, ...
Nature genetics 42 (8), 715-721, 2010
8082010
Prognostically relevant gene signatures of high-grade serous ovarian carcinoma
RGW Verhaak, P Tamayo, JY Yang, D Hubbard, H Zhang, CJ Creighton, ...
The Journal of clinical investigation 123 (1), 2012
6742012
PTEN loss contributes to erlotinib resistance in EGFR-mutant lung cancer by activation of Akt and EGFR
ML Sos, M Koker, BA Weir, S Heynck, R Rabinovsky, T Zander, ...
Cancer research 69 (8), 3256-3261, 2009
6622009
Highly parallel identification of essential genes in cancer cells
B Luo, HW Cheung, A Subramanian, T Sharifnia, M Okamoto, X Yang, ...
Proceedings of the National Academy of Sciences 105 (51), 20380-20385, 2008
6512008
The histone methyltransferase SETDB1 is recurrently amplified in melanoma and accelerates its onset
CJ Ceol, Y Houvras, J Jane-Valbuena, S Bilodeau, DA Orlando, V Battisti, ...
Nature 471 (7339), 513-517, 2011
6312011
ErbB-3 mediates phosphoinositide 3-kinase activity in gefitinib-sensitive non-small cell lung cancer cell lines
JA Engelman, PA Jänne, C Mermel, J Pearlberg, T Mukohara, C Fleet, ...
Proceedings of the National Academy of Sciences 102 (10), 3788-3793, 2005
6152005
RB loss in resistant EGFR mutant lung adenocarcinomas that transform to small-cell lung cancer
MJ Niederst, LV Sequist, JT Poirier, CH Mermel, EL Lockerman, ...
Nature communications 6 (1), 6377, 2015
6112015
El sistema no puede realizar la operación en estos momentos. Inténtalo de nuevo más tarde.
Artículos 1–20