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Jaecheol Lee
Jaecheol Lee
Associate Professor, School of Pharmacy, Sungkyunkwan University
Dirección de correo verificada de skku.edu - Página principal
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Patient-specific iPSC-derived endothelial cells uncover pathways that protect against pulmonary hypertension in BMPR2 mutation carriers
M Gu, NY Shao, S Sa, D Li, V Termglinchan, M Ameen, I Karakikes, ...
Cell stem cell 20 (4), 490-504. e5, 2017
2112017
Epigenetic regulation of phosphodiesterases 2A and 3A underlies compromised β-adrenergic signaling in an iPSC model of dilated cardiomyopathy
H Wu, J Lee, LG Vincent, Q Wang, M Gu, F Lan, JM Churko, KI Sallam, ...
Cell stem cell 17 (1), 89-100, 2015
2012015
Activation of PDGF pathway links LMNA mutation to dilated cardiomyopathy
J Lee, V Termglinchan, S Diecke, I Itzhaki, CK Lam, P Garg, E Lau, ...
Nature 572 (7769), 335-340, 2019
1882019
Defining human cardiac transcription factor hierarchies using integrated single-cell heterogeneity analysis
JM Churko, P Garg, B Treutlein, M Venkatasubramanian, H Wu, J Lee, ...
Nature communications 9 (1), 4906, 2018
1872018
Human-induced pluripotent stem cell model of trastuzumab-induced cardiac dysfunction in patients with breast cancer
T Kitani, SG Ong, CK Lam, JW Rhee, JZ Zhang, A Oikonomopoulos, N Ma, ...
Circulation 139 (21), 2451-2465, 2019
1772019
Large-scale single-cell RNA-seq reveals molecular signatures of heterogeneous populations of human induced pluripotent stem cell-derived endothelial cells
DT Paik, L Tian, J Lee, N Sayed, IY Chen, S Rhee, JW Rhee, Y Kim, ...
Circulation research 123 (4), 443-450, 2018
1462018
Characterization of the molecular mechanisms underlying increased ischemic damage in the aldehyde dehydrogenase 2 genetic polymorphism using a human induced pluripotent stem …
AD Ebert, K Kodo, P Liang, H Wu, BC Huber, J Riegler, J Churko, J Lee, ...
Science translational medicine 6 (255), 255ra130-255ra130, 2014
1252014
Modelling diastolic dysfunction in induced pluripotent stem cell-derived cardiomyocytes from hypertrophic cardiomyopathy patients
H Wu, H Yang, JW Rhee, JZ Zhang, CK Lam, K Sallam, ACY Chang, ...
European heart journal 40 (45), 3685-3695, 2019
1242019
A premature termination codon mutation in MYBPC3 causes hypertrophic cardiomyopathy via chronic activation of nonsense-mediated decay
T Seeger, R Shrestha, CK Lam, C Chen, WL McKeithan, E Lau, ...
Circulation 139 (6), 799-811, 2019
1222019
Transcriptional repression of cancer stem cell marker CD133 by tumor suppressor p53
EK Park, JC Lee, JW Park, SY Bang, SA Yi, BK Kim, JH Park, SH Kwon, ...
Cell death & disease 6 (11), e1964-e1964, 2015
1042015
Contractile force generation by 3D hiPSC-derived cardiac tissues is enhanced by rapid establishment of cellular interconnection in matrix with muscle-mimicking stiffness
S Lee, V Serpooshan, X Tong, S Venkatraman, M Lee, J Lee, O Chirikian, ...
Biomaterials 131, 111-120, 2017
922017
Novel codon-optimized mini-intronic plasmid for efficient, inexpensive and xeno-free induction of pluripotency
S Diecke, J Lu, J Lee, V Termglinchan, NG Kooreman, PW Burridge, ...
Scientific reports 5 (1), 8081, 2015
862015
S6K1 phosphorylation of H2B mediates EZH2 trimethylation of H3: a determinant of early adipogenesis
SA Yi, SH Um, J Lee, JH Yoo, SY Bang, EK Park, MG Lee, KH Nam, ...
Molecular cell 62 (3), 443-452, 2016
802016
Histone deacetylase inhibitor apicidin downregulates DNA methyltransferase 1 expression and induces repressive histone modifications via recruitment of corepressor complex to …
JS You, JK Kang, EK Lee, JC Lee, SH Lee, YJ Jeon, DH Koh, SH Ahn, ...
Oncogene 27 (10), 1376-1386, 2008
792008
Depletion of embryonic stem cell signature by histone deacetylase inhibitor in NCCIT cells: involvement of Nanog suppression
JS You, JK Kang, DW Seo, JH Park, JW Park, JC Lee, YJ Jeon, EJ Cho, ...
Cancer research 69 (14), 5716-5725, 2009
732009
Protein L-isoaspartyl methyltransferase regulates p53 activity
JC Lee, SU Kang, Y Jeon, JW Park, JS You, SW Ha, N Bae, G Lubec, ...
Nature communications 3 (1), 927, 2012
672012
Recent technological updates and clinical applications of induced pluripotent stem cells
S Diecke, SM Jung, J Lee, JH Ju
The Korean journal of internal medicine 29 (5), 547, 2014
662014
A comprehensive TALEN-based knockout library for generating human-induced pluripotent stem cell–based models for cardiovascular diseases
I Karakikes, V Termglinchan, DA Cepeda, J Lee, S Diecke, A Hendel, ...
Circulation Research 120 (10), 1561-1571, 2017
652017
Infection of brain organoids and 2D cortical neurons with SARS-CoV-2 pseudovirus
SA Yi, KH Nam, J Yun, D Gim, D Joe, YH Kim, HJ Kim, JW Han, J Lee
Viruses 12 (9), 1004, 2020
592020
Histone deacetylase inhibitor apicidin induces cyclin E expression through Sp1 sites
S Kim, JK Kang, YK Kim, DW Seo, SH Ahn, JC Lee, CH Lee, JS You, ...
Biochemical and biophysical research communications 342 (4), 1168-1173, 2006
552006
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Artículos 1–20