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Reijo Laaksonen
Reijo Laaksonen
Tampere University
Dirección de correo verificada de tuni.fi
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Heart disease and stroke statistics—2014 update: a report from the American Heart Association
AS Go, D Mozaffarian, VL Roger, EJ Benjamin, JD Berry, MJ Blaha, S Dai, ...
circulation 129 (3), e28-e292, 2014
170782014
Biological, clinical and population relevance of 95 loci for blood lipids
TM Teslovich, K Musunuru, AV Smith, AC Edmondson, IM Stylianou, ...
Nature 466 (7307), 707-713, 2010
41392010
Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease
H Schunkert, IR König, S Kathiresan, MP Reilly, TL Assimes, H Holm, ...
Nature genetics 43 (4), 333-338, 2011
22562011
Large-scale association analysis identifies new risk loci for coronary artery disease
CARDIoGRAMplusC4D Consortium, P Deloukas, S Kanoni, C Willenborg, ...
Nature genetics 45 (1), 25-33, 2013
17802013
New genetic loci link adipose and insulin biology to body fat distribution
D Shungin, TW Winkler, DC Croteau-Chonka, T Ferreira, AE Locke, ...
Nature 518 (7538), 187-196, 2015
16902015
Risk of acute coronary events and serum concentration of asymmetrical dimethylarginine
VP Valkonen, H Päivä, JT Salonen, TA Lakka, T Lehtimäki, J Laakso, ...
The Lancet 358 (9299), 2127-2128, 2001
8062001
Plasma ceramides predict cardiovascular death in patients with stable coronary artery disease and acute coronary syndromes beyond LDL-cholesterol
R Laaksonen, K Ekroos, M Sysi-Aho, M Hilvo, T Vihervaara, D Kauhanen, ...
European heart journal 37 (25), 1967-1976, 2016
5862016
miR-21, miR-210, miR-34a, and miR-146a/b are up-regulated in human atherosclerotic plaques in the Tampere Vascular Study
E Raitoharju, LP Lyytikäinen, M Levula, N Oksala, A Mennander, ...
Atherosclerosis 219 (1), 211-217, 2011
5382011
Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function
C Pattaro, A Teumer, M Gorski, AY Chu, M Li, V Mijatovic, M Garnaas, ...
Nature communications 7 (1), 10023, 2016
5162016
Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants
M Dichgans, R Malik, IR König, J Rosand, R Clarke, S Gretarsdottir, ...
Stroke 45 (1), 24-36, 2014
3932014
High‐dose statins and skeletal muscle metabolism in humans: a randomized, controlled trial
H Päivä, KM Thelen, R Van Coster, J Smet, B De Paepe, KM Mattila, ...
Clinical Pharmacology & Therapeutics 78 (1), 60-68, 2005
3872005
Low-density lipoprotein-independent effects of statins
J Davignon, R Laaksonen
Current opinion in lipidology 10 (6), 543-560, 1999
3531999
Circulating ceramides predict cardiovascular outcomes in the population-based FINRISK 2002 cohort
AS Havulinna, M Sysi-Aho, M Hilvo, D Kauhanen, R Hurme, K Ekroos, ...
Arteriosclerosis, thrombosis, and vascular biology 36 (12), 2424-2430, 2016
3202016
Phenotype standardization for statin‐induced myotoxicity
A Alfirevic, D Neely, J Armitage, H Chinoy, RG Cooper, R Laaksonen, ...
Clinical Pharmacology & Therapeutics 96 (4), 470-476, 2014
2522014
Development and validation of a ceramide-and phospholipid-based cardiovascular risk estimation score for coronary artery disease patients
M Hilvo, PJ Meikle, ER Pedersen, GS Tell, I Dhar, H Brenner, B Schöttker, ...
European heart journal 41 (3), 371-380, 2020
2452020
Molecular Lipids Identify Cardiovascular Risk and Are Efficiently Lowered by Simvastatin and PCSK9 Deficiency
K Tarasov, K Ekroos, M Suoniemi, D Kauhanen, T Sylvänne, R Hurme, ...
The Journal of Clinical Endocrinology & Metabolism 99 (1), E45-E52, 2014
2452014
Design of the Coronary ARtery DIsease Genome-Wide Replication And Meta-Analysis (CARDIoGRAM) Study: a genome-wide association meta-analysis involving more than 22 000 cases and …
M Preuss, IR König, JR Thompson, J Erdmann, D Absher, TL Assimes, ...
Circulation: Cardiovascular Genetics 3 (5), 475-483, 2010
2442010
A systems biology strategy reveals biological pathways and plasma biomarker candidates for potentially toxic statin-induced changes in muscle
R Laaksonen, M Katajamaa, H Päivä, M Sysi-Aho, L Saarinen, P Junni, ...
PloS one 1 (1), e97, 2006
2352006
The effect of simvastatin treatment on natural antioxidants in low-density lipoproteins and high-energy phosphates and ubiquinone in skeletal muscle
R Laaksonen, K Jokelainen, J Laakso, T Sahi, M Härkönen, MJ Tikkanen, ...
The American journal of cardiology 77 (10), 851-854, 1996
2341996
Decreases in serum ubiquinone concentrations do not result in reduced levels in muscle tissue during short‐term simvastatin treatment in humans
R Laaksonen, K Jokelainen, T Sahi, MJ Tikkanen, JJ Himberg
Clinical Pharmacology & Therapeutics 57 (1), 62-66, 1995
2271995
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