Maternal immune activation alters fetal brain development through interleukin-6 SEP Smith, J Li, K Garbett, K Mirnics, PH Patterson Journal of Neuroscience 27 (40), 10695-10702, 2007 | 1857 | 2007 |
Activation of the maternal immune system during pregnancy alters behavioral development of rhesus monkey offspring MD Bauman, AM Iosif, SEP Smith, C Bregere, DG Amaral, PH Patterson Biological psychiatry 75 (4), 332-341, 2014 | 335 | 2014 |
Activation of the maternal immune system alters cerebellar development in the offspring L Shi, SEP Smith, N Malkova, D Tse, Y Su, PH Patterson Brain, behavior, and immunity 23 (1), 116-123, 2009 | 331 | 2009 |
Increased gene dosage of Ube3a results in autism traits and decreased glutamate synaptic transmission in mice SEP Smith, YD Zhou, G Zhang, Z Jin, DC Stoppel, MP Anderson Science translational medicine 3 (103), 103ra97-103ra97, 2011 | 304 | 2011 |
Arrested maturation of excitatory synapses in autosomal dominant lateral temporal lobe epilepsy YD Zhou, S Lee, Z Jin, M Wright, SEP Smith, MP Anderson Nature medicine 15 (10), 1208-1214, 2009 | 206 | 2009 |
Maternal immune activation alters nonspatial information processing in the hippocampus of the adult offspring HT Ito, SEP Smith, E Hsiao, PH Patterson Brain, behavior, and immunity 24 (6), 930-941, 2010 | 163 | 2010 |
Maternal immune activation in nonhuman primates alters social attention in juvenile offspring CJ Machado, AM Whitaker, SEP Smith, PH Patterson, MD Bauman Biological psychiatry 77 (9), 823-832, 2015 | 157 | 2015 |
Reintroduction of the archaic variant of NOVA1 in cortical organoids alters neurodevelopment CA Trujillo, ES Rice, NK Schaefer, IA Chaim, EC Wheeler, AA Madrigal, ... Science 371 (6530), eaax2537, 2021 | 142 | 2021 |
Ultrasensitive measurement of huntingtin protein in cerebrospinal fluid demonstrates increase with Huntington disease stage and decrease following brain huntingtin suppression AL Southwell, SEP Smith, TR Davis, NS Caron, EB Villanueva, Y Xie, ... Scientific reports 5 (1), 12166, 2015 | 116 | 2015 |
Preliminary evidence of neuropathology in nonhuman primates prenatally exposed to maternal immune activation RK Weir, R Forghany, SEP Smith, PH Patterson, AK McAllister, ... Brain, behavior, and immunity 48, 139-146, 2015 | 95 | 2015 |
Mutant huntingtin is cleared from the brain via active mechanisms in Huntington disease NS Caron, R Banos, C Yanick, AE Aly, LM Byrne, ED Smith, Y Xie, ... Journal of Neuroscience 41 (4), 780-796, 2021 | 65 | 2021 |
Altered network and rescue of human neurons derived from individuals with early-onset genetic epilepsy PD Negraes, CA Trujillo, NK Yu, W Wu, H Yao, N Liang, JD Lautz, E Kwok, ... Molecular psychiatry 26 (11), 7047-7068, 2021 | 60 | 2021 |
Maternal immune activation increases neonatal mouse cortex thickness and cell density SEP Smith, RM Elliott, MP Anderson Journal of Neuroimmune Pharmacology 7, 529-532, 2012 | 43 | 2012 |
Reciprocal regulation among TRPV1 channels and phosphoinositide 3-kinase in response to nerve growth factor A Stratiievska, S Nelson, EN Senning, JD Lautz, SEP Smith, SE Gordon Elife 7, e38869, 2018 | 35 | 2018 |
Resolving the synaptic versus developmental dichotomy of autism risk genes WE Heavner, SEP Smith Trends in neurosciences 43 (4), 227-241, 2020 | 34 | 2020 |
Synaptic activity induces input‐specific rearrangements in a targeted synaptic protein interaction network JD Lautz, EA Brown, AA Williams VanSchoiack, SEP Smith Journal of neurochemistry 146 (5), 540-559, 2018 | 33 | 2018 |
Multiplex matrix network analysis of protein complexes in the human TCR signalosome SEP Smith, SC Neier, BK Reed, TR Davis, JP Sinnwell, JE Eckel-Passow, ... Science signaling 9 (439), rs7-rs7, 2016 | 32 | 2016 |
Maternal immune activation, cytokines and autism AW Zimmerman, PH Patterson, W Xu, SEP Smith, BE Devarman Autism: current theories and evidence, 289-307, 2008 | 30 | 2008 |
Clustering the autisms using glutamate synapse protein interaction networks from cortical and hippocampal tissue of seven mouse models EA Brown, JD Lautz, TR Davis, EP Gniffke, AAW VanSchoiack, SC Neier, ... Molecular autism 9, 1-16, 2018 | 27 | 2018 |
A repurposed drug screen identifies compounds that inhibit the binding of the COVID-19 spike protein to ACE2 KB Tsegay, CM Adeyemi, EP Gniffke, DN Sather, JK Walker, SEP Smith Frontiers in pharmacology 12, 685308, 2021 | 21 | 2021 |