| Microglia promote learning-dependent synapse formation through brain-derived neurotrophic factor CN Parkhurst, G Yang, I Ninan, JN Savas, JR Yates, JJ Lafaille, ... Cell 155 (7), 1596-1609, 2013 | 2663 | 2013 |
| Dopamine oxidation mediates mitochondrial and lysosomal dysfunction in Parkinson’s disease LF Burbulla, P Song, JR Mazzulli, E Zampese, YC Wong, S Jeon, ... Science 357 (6357), 1255-1261, 2017 | 790 | 2017 |
| Identification of long-lived proteins reveals exceptional stability of essential cellular structures BH Toyama, JN Savas, SK Park, MS Harris, NT Ingolia, JR Yates, ... Cell 154 (5), 971-982, 2013 | 587 | 2013 |
| Acetylation targets mutant huntingtin to autophagosomes for degradation H Jeong, F Then, TJ Melia, JR Mazzulli, L Cui, JN Savas, C Voisine, ... Cell 137 (1), 60-72, 2009 | 493 | 2009 |
| Phenotypic differences in hiPSC NPCs derived from patients with schizophrenia K Brennand, JN Savas, Y Kim, N Tran, A Simone, K Hashimoto-Torii, ... Molecular psychiatry 20 (3), 361-368, 2015 | 435 | 2015 |
| LRRTM2 interacts with Neurexin1 and regulates excitatory synapse formation J De Wit, E Sylwestrak, ML O'Sullivan, S Otto, K Tiglio, JN Savas, ... Neuron 64 (6), 799-806, 2009 | 422 | 2009 |
| Sirt1 mediates neuroprotection from mutant huntingtin by activation of the TORC1 and CREB transcriptional pathway H Jeong, DE Cohen, L Cui, A Supinski, JN Savas, JR Mazzulli, ... Nature medicine 18 (1), 159-165, 2012 | 408 | 2012 |
| Extremely long-lived nuclear pore proteins in the rat brain JN Savas, BH Toyama, T Xu, JR Yates III, MW Hetzer Science 335 (6071), 942-942, 2012 | 335 | 2012 |
| Secreted amyloid-β precursor protein functions as a GABABR1a ligand to modulate synaptic transmission HC Rice, D De Malmazet, A Schreurs, S Frere, I Van Molle, AN Volkov, ... Science 363 (6423), eaao4827, 2019 | 292 | 2019 |
| FLRT proteins are endogenous latrophilin ligands and regulate excitatory synapse development ML O'Sullivan, J de Wit, JN Savas, D Comoletti, S Otto-Hitt, JR Yates, ... Neuron 73 (5), 903-910, 2012 | 281 | 2012 |
| Progressive accumulation of amyloid‐β oligomers in Alzheimer’s disease and in amyloid precursor protein transgenic mice is accompanied by selective alterations … E Pham, L Crews, K Ubhi, L Hansen, A Adame, A Cartier, D Salmon, ... The FEBS journal 277 (14), 3051-3067, 2010 | 263 | 2010 |
| Differences in AMPA and kainate receptor interactomes facilitate identification of AMPA receptor auxiliary subunit GSG1L NF Shanks, JN Savas, T Maruo, O Cais, A Hirao, S Oe, A Ghosh, Y Noda, ... Cell reports 1 (6), 590-598, 2012 | 210 | 2012 |
| Huntington's disease protein contributes to RNA-mediated gene silencing through association with Argonaute and P bodies JN Savas, A Makusky, S Ottosen, D Baillat, F Then, D Krainc, ... Proceedings of the National Academy of Sciences 105 (31), 10820-10825, 2008 | 188 | 2008 |
| Unbiased discovery of glypican as a receptor for LRRTM4 in regulating excitatory synapse development J de Wit, ML O’Sullivan, JN Savas, G Condomitti, MC Caccese, ... Neuron 79 (4), 696-711, 2013 | 185 | 2013 |
| Resetting the epigenetic balance of Polycomb and COMPASS function at enhancers for cancer therapy L Wang, Z Zhao, PA Ozark, D Fantini, SA Marshall, EJ Rendleman, ... Nature medicine 24 (6), 758-769, 2018 | 158 | 2018 |
| Genomic analysis of 220 CTCLs identifies a novel recurrent gain-of-function alteration in RLTPR (p. Q575E) J Park, J Yang, AT Wenzel, A Ramachandran, WJ Lee, JC Daniels, J Kim, ... Blood, The Journal of the American Society of Hematology 130 (12), 1430-1440, 2017 | 151 | 2017 |
| Proteomic analysis of wild-type and mutant huntingtin-associated proteins in mouse brains identifies unique interactions and involvement in protein synthesis BP Culver, JN Savas, SK Park, JH Choi, S Zheng, SO Zeitlin, JR Yates, ... Journal of Biological Chemistry 287 (26), 21599-21614, 2012 | 147 | 2012 |
| The Rqc2/Tae2 subunit of the ribosome-associated quality control (RQC) complex marks ribosome-stalled nascent polypeptide chains for aggregation R Yonashiro, EB Tahara, MH Bengtson, M Khokhrina, H Lorenz, KC Chen, ... Elife 5, e11794, 2016 | 139 | 2016 |
| A role for huntington disease protein in dendritic RNA granules JN Savas, B Ma, K Deinhardt, BP Culver, S Restituito, L Wu, JG Belasco, ... Journal of Biological Chemistry 285 (17), 13142-13153, 2010 | 114 | 2010 |
| Microarray analysis of the hyperthermophilic archaeon Pyrococcus furiosus exposed to gamma irradiation E Williams, TM Lowe, J Savas, J DiRuggiero Extremophiles 11, 19-29, 2007 | 105 | 2007 |
