Local and global cytosolic Ca2+ oscillations in exocrine cells evoked by agonists and inositol trisphosphate P Thorn, AM Lawrie, PM Smith, DV Gallacher, OH Petersen Cell 74 (4), 661-668, 1993 | 558 | 1993 |
Hyaluronic acid modified mesoporous silica nanoparticles for targeted drug delivery to CD44-overexpressing cancer cells M Yu, S Jambhrunkar, P Thorn, J Chen, W Gu, C Yu Nanoscale 5 (1), 178-183, 2013 | 369 | 2013 |
Cyclic ADP‐ribose regulation of ryanodine receptors involved in agonist evoked cytosolic Ca2+ oscillations in pancreatic acinar cells. P Thorn, O Gerasimenko, OH Petersen The EMBO journal 13 (9), 2038-2043, 1994 | 252 | 1994 |
Paclitaxel affects cytosolic calcium signals by opening the mitochondrial permeability transition pore JF Kidd, MF Pilkington, MJ Schell, KE Fogarty, JN Skepper, CW Taylor, ... Journal of Biological Chemistry 277 (8), 6504-6510, 2002 | 249 | 2002 |
Intracellular Ca2+ and Cl– Channel Activation in Secretory Cells JF Kidd, P Thorn Annual review of physiology 62 (1), 493-513, 2000 | 143 | 2000 |
Zymogen granule exocytosis is characterized by long fusion pore openings and preservation of vesicle lipid identity P Thorn, KE Fogarty, I Parker Proceedings of the National Academy of Sciences 101 (17), 6774-6779, 2004 | 136 | 2004 |
Calcium signalling: IP3 rises again… and again CW Taylor, P Thorn Current Biology 11 (9), R352-R355, 2001 | 109 | 2001 |
Cell polarity defines three distinct domains in pancreatic β-cells WJ Gan, M Zavortink, C Ludick, R Templin, R Webb, R Webb, W Ma, ... Journal of cell science 130 (1), 143-151, 2017 | 99 | 2017 |
Vesicle-associated membrane protein 8 (VAMP8) is a SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) selectively required for sequential granule-to … N Behrendorff, S Dolai, W Hong, HY Gaisano, P Thorn Journal of Biological Chemistry 286 (34), 29627-29634, 2011 | 98 | 2011 |
Insulin secretion from beta cells in intact mouse islets is targeted towards the vasculature JT Low, M Zavortink, JM Mitchell, WJ Gan, OH Do, CJ Schwiening, ... Diabetologia 57, 1655-1663, 2014 | 97 | 2014 |
Activation of nonselective cation channels by physiological cholecystokinin concentrations in mouse pancreatic acinar cells. P Thorn, OH Petersen Journal of General Physiology 100 (1), 11-25, 1992 | 97 | 1992 |
A simple approach to prepare monodisperse mesoporous silica nanospheres with adjustable sizes M Yu, L Zhou, J Zhang, P Yuan, P Thorn, W Gu, C Yu Journal of colloid and interface science 376 (1), 67-75, 2012 | 96 | 2012 |
Protons released during pancreatic acinar cell secretion acidify the lumen and contribute to pancreatitis in mice N Behrendorff, M Floetenmeyer, C Schwiening, P Thorn Gastroenterology 139 (5), 1711-1720. e5, 2010 | 87 | 2010 |
Regulation of adenylyl cyclase by membrane potential DMF Cooper, MJ Schell, P Thorn, RF Irvine Journal of Biological Chemistry 273 (42), 27703-27707, 1998 | 86 | 1998 |
Cytosolic Ca2+ spikes evoked by the thiol reagent thimerosal in both intact and internally perfused single pancreatic acinar cells P Thorn, P Brady, J Llopis, DV Gallacher, OH Petersen Pflügers Archiv 422, 173-178, 1992 | 80 | 1992 |
The role of the islet niche on beta cell structure and function E Lammert, P Thorn Journal of molecular biology 432 (5), 1407-1418, 2020 | 78 | 2020 |
Dynamic regulation of the large exocytotic fusion pore in pancreatic acinar cells O Larina, P Bhat, JA Pickett, BS Launikonis, A Shah, WA Kruger, ... Molecular biology of the cell 18 (9), 3502-3511, 2007 | 77 | 2007 |
Local integrin activation in pancreatic β cells targets insulin secretion to the vasculature WJ Gan, OH Do, L Cottle, W Ma, E Kosobrodova, J Cooper-White, M Bilek, ... Cell reports 24 (11), 2819-2826. e3, 2018 | 76 | 2018 |
Ca2+ oscillations in pancreatic acinar cells: spatiotemporal relationships and functional implications P Thorn, AM Lawrie, PM Smith, DV Gallacher, OH Petersen Cell calcium 14 (10), 746-757, 1993 | 75 | 1993 |
Ex vivo human pancreatic slice preparations offer a valuable model for studying pancreatic exocrine biology T Liang, S Dolai, L Xie, E Winter, AI Orabi, N Karimian, LI Cosen-Binker, ... Journal of Biological Chemistry 292 (14), 5957-5969, 2017 | 71 | 2017 |