Laszlo Nagy

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Peter TontonozProfessor of Pathology and Laboratory Medicine, UCLAVerified email at mednet.ucla.edu
Istvan SzatmariUniversity of DebrecenVerified email at med.unideb.hu
Attila HorvathSenior Post-Doctoral Fellow, PeterMac and The University of MelbourneVerified email at petermac.org
Balint, Balint LaszloUniversity of DebrecenVerified email at med.unideb.hu
Zoltan SimandiPostdoctoral Researcher, University of PennsylvaniaVerified email at seas.upenn.edu
Ixchelt Cuaranta MonroyResearcher UASLPVerified email at uaslp.mx
Eva RajnavolgyiUniversity of Debrecen Medical and Health Science Centre Department of ImmunologyVerified email at med.unideb.hu
Richard J. Lin, MD, PhDMemorial Sloan Kettering Cancer CenterVerified email at mskcc.org
Ralph RühlCISCAREX UG, Berlin, GermanyVerified email at ciscarex.com
Szilvia Benkőuniversity of debrecen, department of physiologyVerified email at med.unideb.hu
Endre BartaAgricultural Biotechnology Center, University of DebrecenVerified email at abc.naik.hu
Bertalan Meskó, MD, PhDDirector of The Medical Futurist InstituteVerified email at med.unideb.hu
Peter GogolakUniversity of DebrecenVerified email at med.unideb.hu
Máté KissUniversity of GenevaVerified email at unige.ch
György VámosiSenior scientist, Department of Biophysics and Cell Biology, University of DebrecenVerified email at med.unideb.hu
Zoltán SzekaneczProfessor of Rheumatology, Immunology and Medicine, University of Debrecen Faculty of MedicineVerified email at med.unideb.hu
Peter Brazdaassistant professor, University Medical Center Utrecht, Center for Translational ImmunologyVerified email at umcutrecht.nl
Christos C. ZouboulisProf. Dr. med. Prof. honoraire Dr. h.c. - Staedtisches Klinikum Dessau, Brandenburg Medical SchoolVerified email at mhb-fontane.de
Eva RemenyikProfessor of DermatologyVerified email at med.unideb.hu
Károly Palatkahabil. egyetemi docens, gasztroenterológus, belgyógyász, Debreceni Egyetem Belgyógyászati IntézetVerified email at med.unideb.hu

Laszlo Nagy

Professor and Co-Director, Johns Hopkins University School of Medicine and University of Debrecen

Verified email at jhmi.edu - Homepage

epigenomics transcription nuclear hormone receptors macrophages metabolism


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PPARγ promotes monocyte/macrophage differentiation and uptake of oxidized LDL P Tontonoz, L Nagy, JGA Alvarez, VA Thomazy, RM Evans Cell 93 (2), 241-252, 1998	2400	1998
Oxidized LDL regulates macrophage gene expression through ligand activation of PPARγ L Nagy, P Tontonoz, JGA Alvarez, H Chen, RM Evans Cell 93 (2), 229-240, 1998	2376	1998
Nuclear receptor coactivator ACTR is a novel histone acetyltransferase and forms a multimeric activation complex with P/CAF and CBP/p300 H Chen, RJ Lin, RL Schiltz, D Chakravarti, A Nash, L Nagy, ML Privalsky, ... Cell 90 (3), 569-580, 1997	1891	1997
A PPARγ-LXR-ABCA1 pathway in macrophages is involved in cholesterol efflux and atherogenesis A Chawla, WA Boisvert, CH Lee, BA Laffitte, Y Barak, SB Joseph, D Liao, ... Molecular cell 7 (1), 161-171, 2001	1743	2001
Nuclear receptor repression mediated by a complex containing SMRT, mSin3A, and histone deacetylase L Nagy, HY Kao, D Chakravarti, RJ Lin, CA Hassig, DE Ayer, ... Cell 89 (3), 373-380, 1997	1644	1997
Role of the histone deacetylase complex in acute promyelocytic leukaemia RJ Lin, L Nagy, S Inoue, W Shao, WH Miller Jr, RM Evans Nature 391 (6669), 811-814, 1998	1438	1998
PPAR-γ dependent and independent effects on macrophage-gene expression in lipid metabolism and inflammation A Chawla, Y Barak, L Nagy, D Liao, P Tontonoz, RM Evans Nature medicine 7 (1), 48-52, 2001	1362	2001
PPARs are a unique set of fatty acid regulated transcription factors controlling both lipid metabolism and inflammation T Varga, Z Czimmerer, L Nagy Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1812 (8 …, 2011	1007	2011
Structural basis for the activation of PPARγ by oxidized fatty acids T Itoh, L Fairall, K Amin, Y Inaba, A Szanto, BL Balint, L Nagy, ... Nature structural & molecular biology 15 (9), 924-931, 2008	537	2008
Mechanism of corepressor binding and release from nuclear hormone receptors L Nagy, HY Kao, JD Love, C Li, E Banayo, JT Gooch, V Krishna, ... Genes & development 13 (24), 3209-3216, 1999	521	1999
Mechanism of the nuclear receptor molecular switch L Nagy, JWR Schwabe Trends in biochemical sciences 29 (6), 317-324, 2004	502	2004
STAT6 transcription factor is a facilitator of the nuclear receptor PPARγ-regulated gene expression in macrophages and dendritic cells A Szanto, BL Balint, ZS Nagy, E Barta, B Dezso, A Pap, L Szeles, ... Immunity 33 (5), 699-712, 2010	492	2010
Role for peroxisome proliferator-activated receptor α in oxidized phospholipid–induced synthesis of monocyte chemotactic protein-1 and interleukin-8 by endothelial cells H Lee, W Shi, P Tontonoz, S Wang, G Subbanagounder, CC Hedrick, ... Circulation research 87 (6), 516-521, 2000	379	2000
Retinoid X receptors: X-ploring their (patho) physiological functions A Szanto, V Narkar, Q Shen, IP Uray, PJA Davies, L Nagy Cell Death & Differentiation 11 (2), S126-S143, 2004	358	2004
1, 25-dihydroxyvitamin D3 is an autonomous regulator of the transcriptional changes leading to a tolerogenic dendritic cell phenotype L Széles, G Keresztes, D Töröcsik, Z Balajthy, L Krenács, S Póliska, ... The Journal of Immunology 182 (4), 2074-2083, 2009	284	2009
Activation of retinoid X receptors induces apoptosis in HL-60 cell lines L Nagy, VA Thomázy, GL Shipley, L Fésüs, W Lamph, RA Heyman, ... Molecular and cellular biology 15 (7), 3540-3551, 1995	279	1995
Nuclear hormone receptors enable macrophages and dendritic cells to sense their lipid environment and shape their immune response L Nagy, A Szanto, I Szatmari, L Széles Physiological reviews 92 (2), 739-789, 2012	261	2012
PPARγ controls CD1d expression by turning on retinoic acid synthesis in developing human dendritic cells I Szatmari, A Pap, R Rühl, JX Ma, PA Illarionov, GS Besra, ... The Journal of experimental medicine 203 (10), 2351-2362, 2006	257	2006
Peroxisome proliferator-activated receptor γ-regulated ABCG2 expression confers cytoprotection to human dendritic cells I Szatmari, G Vámosi, P Brazda, BL Balint, S Benko, L Széles, V Jeney, ... Journal of Biological Chemistry 281 (33), 23812-23823, 2006	232	2006
The transcription factor STAT6 mediates direct repression of inflammatory enhancers and limits activation of alternatively polarized macrophages Z Czimmerer, B Daniel, A Horvath, D Rückerl, G Nagy, M Kiss, M Peloquin, ... Immunity 48 (1), 75-90. e6, 2018	230	2018

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