| Intestinal microbiota metabolism of l-carnitine, a nutrient in red meat, promotes atherosclerosis RA Koeth, Z Wang, BS Levison, JA Buffa, E Org, BT Sheehy, EB Britt, X Fu, ... Nature medicine 19 (5), 576-585, 2013 | 4851 | 2013 |
| Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk CKDGen Consortium, KidneyGen Consortium, EchoGen consortium, ... Nature 478 (7367), 103-109, 2011 | 2370 | 2011 |
| Gut microbial metabolite TMAO enhances platelet hyperreactivity and thrombosis risk W Zhu, JC Gregory, E Org, JA Buffa, N Gupta, Z Wang, L Li, X Fu, Y Wu, ... Cell 165 (1), 111-124, 2016 | 1901 | 2016 |
| Genome-wide association study identifies eight loci associated with blood pressure C Newton-Cheh, T Johnson, V Gateva, MD Tobin, M Bochud, L Coin, ... Nature genetics 41 (6), 666-676, 2009 | 1456 | 2009 |
| Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits E Evangelou, HR Warren, D Mosen-Ansorena, B Mifsud, R Pazoki, H Gao, ... Nature genetics 50 (10), 1412-1425, 2018 | 1380 | 2018 |
| Non-lethal inhibition of gut microbial trimethylamine production for the treatment of atherosclerosis Z Wang, AB Roberts, JA Buffa, BS Levison, W Zhu, E Org, X Gu, Y Huang, ... Cell 163 (7), 1585-1595, 2015 | 1337 | 2015 |
| Large-scale association analyses identify host factors influencing human gut microbiome composition A Kurilshikov, C Medina-Gomez, R Bacigalupe, D Radjabzadeh, J Wang, ... Nature genetics 53 (2), 156-165, 2021 | 1334 | 2021 |
| Polymorphisms in FKBP5 are associated with increased recurrence of depressive episodes and rapid response to antidepressant treatment EB Binder, D Salyakina, P Lichtner, GM Wochnik, M Ising, B Pütz, ... Nature genetics 36 (12), 1319-1325, 2004 | 1159 | 2004 |
| Genome-wide association analyses identify 18 new loci associated with serum urate concentrations A Köttgen, E Albrecht, A Teumer, V Vitart, J Krumsiek, C Hundertmark, ... Nature genetics 45 (2), 145-154, 2013 | 934 | 2013 |
| Sex differences and hormonal effects on gut microbiota composition in mice E Org, M Mehrabian, BW Parks, P Shipkova, X Liu, TA Drake, AJ Lusis Gut microbes 7 (4), 313-322, 2016 | 749 | 2016 |
| Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk HR Warren, E Evangelou, CP Cabrera, H Gao, M Ren, B Mifsud, I Ntalla, ... Nature genetics 49 (3), 403-415, 2017 | 630 | 2017 |
| Genetic control of obesity and gut microbiota composition in response to high-fat, high-sucrose diet in mice BW Parks, E Nam, E Org, E Kostem, F Norheim, ST Hui, C Pan, M Civelek, ... Cell metabolism 17 (1), 141-152, 2013 | 627 | 2013 |
| γ-Butyrobetaine is a proatherogenic intermediate in gut microbial metabolism of L-carnitine to TMAO RA Koeth, BS Levison, MK Culley, JA Buffa, Z Wang, JC Gregory, E Org, ... Cell metabolism 20 (5), 799-812, 2014 | 575 | 2014 |
| A first-generation linkage disequilibrium map of human chromosome 22 E Dawson, GR Abecasis, S Bumpstead, Y Chen, S Hunt, DM Beare, ... Nature 418 (6897), 544-548, 2002 | 552 | 2002 |
| Individual diet has sex-dependent effects on vertebrate gut microbiota DI Bolnick, LK Snowberg, PE Hirsch, CL Lauber, E Org, B Parks, AJ Lusis, ... Nature communications 5 (1), 4500, 2014 | 548 | 2014 |
| Transmission of atherosclerosis susceptibility with gut microbial transplantation JC Gregory, JA Buffa, E Org, Z Wang, BS Levison, W Zhu, MA Wagner, ... Journal of Biological Chemistry 290 (9), 5647-5660, 2015 | 547 | 2015 |
| Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function C Pattaro, A Teumer, M Gorski, AY Chu, M Li, V Mijatovic, M Garnaas, ... Nature communications 7 (1), 10023, 2016 | 529 | 2016 |
| Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure LV Wain, GC Verwoert, PF O'reilly, G Shi, T Johnson, AD Johnson, ... Nature genetics 43 (10), 1005-1011, 2011 | 513 | 2011 |
| SLC2A9 is a high-capacity urate transporter in humans MJ Caulfield, PB Munroe, D O'Neill, K Witkowska, FJ Charchar, ... PLoS medicine 5 (10), e197, 2008 | 447 | 2008 |
| Interactions between Roseburia intestinalis and diet modulate atherogenesis in a murine model K Kasahara, KA Krautkramer, E Org, KA Romano, RL Kerby, EI Vivas, ... Nature microbiology 3 (12), 1461-1471, 2018 | 435 | 2018 |