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Helene Couthon
Helene Couthon
Maître de Conférences
Verified email at univ-brest.fr
Title
Cited by
Cited by
Year
Atherton–Todd reaction: mechanism, scope and applications
SS Le Corre, M Berchel, H Couthon-Gourvès, JP Haelters, PA Jaffrès
Beilstein journal of organic chemistry 10 (1), 1166-1196, 2014
1902014
Phosphonic acid: preparation and applications
CM Sevrain, M Berchel, H Couthon, PA Jaffrès
Beilstein journal of organic chemistry 13 (1), 2186-2213, 2017
1802017
New alkyl-lipid blockers of SK3 channels reduce cancer cell migration and occurrence of metastasis
A Girault, JP Haelters, M Potier-Cartereau, A Chantome, M Pinault, ...
Current cancer drug targets 11 (9), 1111-1125, 2011
762011
Synthesis of gem-bisphosphonic methotrexate conjugates and their biological response towards Walker's osteosarcoma
G Sturtz, H Couthon, O Fabulet, M Mian, S Rosini
European journal of medicinal chemistry 28 (11), 899-903, 1993
761993
Alkyl ether lipids, ion channels and lipid raft reorganization in cancer therapy
PA Jaffres, C Gajate, AM Bouchet, H Couthon-Gourves, A Chantome, ...
Pharmacology & Therapeutics 165, 114-131, 2016
732016
Targeted delivery of antineoplastic agent to bone: biodistribution studies of technetium-99m-labeled gem-bisphosphonate conjugate of methotrexate.
F Hosain, RP Spencer, HM Couthon, GL Sturtz
Journal of Nuclear Medicine: Official Publication, Society of Nuclear …, 1996
711996
Lipophosphonate/lipophosphoramidates: a family of synthetic vectors efficient for gene delivery
M Berchel, T Le Gall, H Couthon-Gourvès, JP Haelters, T Montier, ...
Biochimie 94 (1), 33-41, 2012
562012
The gene transfection properties of a lipophosphoramidate derivative with two phytanyl chains
MF Lindberg, N Carmoy, T Le Gall, A Fraix, M Berchel, C Lorilleux, ...
Biomaterials 33 (26), 6240-6253, 2012
512012
Structural Study of Hydrated/Dehydrated Manganese Thiophene-2,5-diphosphonate Metal Organic Frameworks, Mn2(O3P–C4H2S–PO3)·2H2O
JM Rueff, O Perez, A Pautrat, N Barrier, GB Hix, S Hernot, ...
Inorganic Chemistry 51 (19), 10251-10261, 2012
402012
Towards the syntheses of N‐H and N‐alkylated derivatives of meridianins
B Corbel, FO Michaud, L Meijer, G Simon, H Couthon‐Gourves, ...
Journal of heterocyclic chemistry 44 (4), 793-801, 2007
392007
Cationic lipo-thiophosphoramidates for gene delivery: synthesis, physico-chemical characterization and gene transfection activity–comparison with lipo-phosphoramidates
A Fraix, T Montier, N Carmoy, D Loizeau, L Burel-Deschamps, T Le Gall, ...
Organic & Biomolecular Chemistry 9 (7), 2422-2432, 2011
382011
First general approach to cyclohex-3-ene-1, 1-bis (phosphonates) by Diels− Alder cycloaddition of tetraethyl vinylidenebis (phosphonate) to 1, 3-dienes
R Ruzziconi, G Ricci, A Gioiello, H Couthon-Gourves, JP Gourves
The Journal of Organic Chemistry 68 (3), 736-742, 2003
272003
Singular interaction between an antimetastatic agent and the lipid bilayer: the ohmline case
FE Herrera, CM Sevrain, PA Jaffrès, H Couthon, A Grélard, EJ Dufourc, ...
ACS omega 2 (10), 6361-6370, 2017
252017
3, 5-Diphosphonobenzoic Acid, a New Rigid Heterotrifunctional Building Block to Design Metal Organic Frameworks. Illustration with the Characterization of Cu5 [(O3P) 2-C6H3-CO2 …
JM Rueff, O Perez, C Simon, C Lorilleux, H Couthon-Gourvès, PA Jaffres
Crystal growth & design 9 (10), 4262-4268, 2009
252009
Synthesis of functionalized alkoxyalkylidene gem-bisphosphonates
JP Haelters, H Couthon-Gourves, A Le Goff, G Simon, B Corbel, ...
Tetrahedron 64 (27), 6537-6543, 2008
232008
New disaccharide‐based ether lipids as SK3 ion channel inhibitors
W Berthe, CM Sevrain, A Chantôme, AM Bouchet, M Gueguinou, ...
ChemMedChem 11 (14), 1531-1539, 2016
222016
DiGalactosyl-Glycero-Ether Lipid: synthetic approaches and evaluation as SK3 channel inhibitor
CM Sevrain, JP Haelters, A Chantôme, H Couthon-Gourvès, ...
Organic & Biomolecular Chemistry 11 (27), 4479-4487, 2013
222013
A NEW EFFICIENT SYNTHESIS OF ω-AMINOALKYLIDENE-1, 1-BISPHOSPHONATE TETRAETHYLESTERS
JP Gourves, H Couthon, G Sturtz
Phosphorus, Sulfur, and Silicon and the Related Elements 132 (1), 219-229, 1998
221998
Triggering bilayer to inverted-hexagonal nanostructure formation by thiol–ene click chemistry on cationic lipids: consequences on gene transfection
D Afonso, T Le Gall, H Couthon-Gourvès, A Grélard, S Prakash, ...
Soft matter 12 (20), 4516-4520, 2016
212016
Synthesis of 3,4‐Dihydro‐2H‐pyrido[1,2‐b]isoindol‐1‐one and 3,4‐Dihydro‐2H‐pyrido[1,2‐b]pyrrolidin‐1‐one Functionalized at the C‐6 Position by an …
JP Gourves, H Couthon, G Sturtz
European journal of organic chemistry 1999 (12), 3489-3493, 1999
211999
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