| Inhibition of mTOR by rapamycin abolishes cognitive deficits and reduces amyloid-β levels in a mouse model of Alzheimer's disease P Spilman, N Podlutskaya, MJ Hart, J Debnath, O Gorostiza, D Bredesen, ... PloS one 5 (4), e9979, 2010 | 1167 | 2010 |
| Downregulation of β-catenin by human Axin and its association with the APC tumor suppressor, β-catenin and GSK3β MJ Hart, R De Los Santos, IN Albert, B Rubinfeld, P Polakis Current Biology 8 (10), 573-581, 1998 | 1120 | 1998 |
| p115 RhoGEF, a GTPase activating protein for Gα12 and Gα13 T Kozasa, X Jiang, MJ Hart, PM Sternweis, WD Singer, AG Gilman, ... Science 280 (5372), 2109-2111, 1998 | 1094 | 1998 |
| Direct stimulation of the guanine nucleotide exchange activity of p115 RhoGEF by Gα13 MJ Hart, X Jiang, T Kozasa, W Roscoe, WD Singer, AG Gilman, ... Science 280 (5372), 2112-2114, 1998 | 1047 | 1998 |
| The F-box protein β-TrCP associates with phosphorylated β-catenin and regulates its activity in the cell M Hart, JP Concordet, I Lassot, I Albert, R Del los Santos, H Durand, ... Current biology 9 (4), 207-211, 1999 | 867 | 1999 |
| Catalysis of guanine nucleotide exchange on the CDC42Hs protein by the dbloncogene product MJ Hart, A Eva, T Evans, SA Aaronson, RA Cerione Nature 354 (6351), 311-314, 1991 | 580 | 1991 |
| IQGAP1, a calmodulin‐binding protein with a rasGAP‐related domain, is a potential effector for cdc42Hs. MJ Hart, MG Callow, B Souza, P Polakis The EMBO journal 15 (12), 2997-3005, 1996 | 495 | 1996 |
| Cellular transformation and guanine nucleotide exchange activity are catalyzed by a common domain on the dbl oncogene product. MJ Hart, A Eva, D Zangrilli, SA Aaronson, T Evans, RA Cerione, Y Zheng Journal of Biological Chemistry 269 (1), 62-65, 1994 | 436 | 1994 |
| IQGAP1, a Rac-and Cdc42-binding protein, directly binds and cross-links microfilaments AM Bashour, AT Fullerton, MJ Hart, GS Bloom The Journal of cell biology 137 (7), 1555-1566, 1997 | 329 | 1997 |
| Molecular cloning of the gene for the human placental GTP-binding protein Gp (G25K): identification of this GTP-binding protein as the human homolog of the yeast cell-division … K Shinjo, JG Koland, MJ Hart, V Narasimhan, DI Johnson, T Evans, ... Proceedings of the National Academy of Sciences 87 (24), 9853-9857, 1990 | 302 | 1990 |
| A tyrosine-phosphorylated protein that binds to an important regulatory region on the cool family of p21-activated kinase-binding proteins S Bagrodia, D Bailey, Z Lenard, M Hart, JL Guan, RT Premont, SJ Taylor, ... Journal of Biological Chemistry 274 (32), 22393-22400, 1999 | 275 | 1999 |
| The identification and characterization of a GDP-dissociation inhibitor (GDI) for the CDC42Hs protein D Leonard, MJ Hart, JV Platko, A Eva, W Henzel, T Evans, RA Cerione Journal of Biological Chemistry 267 (32), 22860-22868, 1992 | 239 | 1992 |
| Chronic rapamycin restores brain vascular integrity and function through NO synthase activation and improves memory in symptomatic mice modeling Alzheimer’s disease AL Lin, W Zheng, JJ Halloran, RR Burbank, SA Hussong, MJ Hart, ... Journal of Cerebral Blood Flow & Metabolism 33 (9), 1412-1421, 2013 | 229 | 2013 |
| Chronic inhibition of mammalian target of rapamycin by rapamycin modulates cognitive and non-cognitive components of behavior throughout lifespan in mice J Halloran, SA Hussong, R Burbank, N Podlutskaya, KE Fischer, ... Neuroscience 223, 102-113, 2012 | 229 | 2012 |
| A GDP dissociation inhibitor that serves as a GTPase inhibitor for the Ras-like protein CDC42Hs MJ Hart, Y Maru, D Leonard, ON Witte, T Evans, RA Cerione Science 258 (5083), 812-815, 1992 | 224 | 1992 |
| Identification of a novel guanine nucleotide exchange factor for the Rho GTPase MJ Hart, S Sharma, RG Qiu, P McCabe, P Polakis, G Bollag Journal of Biological Chemistry 271 (41), 25452-25458, 1996 | 212 | 1996 |
| Identification of an actin cytoskeletal complex that includes IQGAP and the Cdc42 GTPase JW Erickson, RA Cerione, MJ Hart Journal of Biological Chemistry 272 (39), 24443-24447, 1997 | 193 | 1997 |
| GDP dissociation inhibitor prevents intrinsic and GTPase activating protein-stimulated GTP hydrolysis by the Rac GTP-binding protein. TH Chuang, X Xu, UG Knaus, MJ Hart, GM Bokoch Journal of Biological Chemistry 268 (2), 775-778, 1993 | 186 | 1993 |
| Cloning and expression of a human CDC42 GTPase-activating protein reveals a functional SH3-binding domain. ET Barfod, Y Zheng, WJ Kuang, MJ Hart, T Evans, RA Cerione, ... Journal of Biological Chemistry 268 (35), 26059-26062, 1993 | 173 | 1993 |
| Platelet endothelial aggregation receptor 1 (PEAR1), a novel epidermal growth factor repeat-containing transmembrane receptor, participates in platelet contact-induced activation N Nanda, M Bao, H Lin, K Clauser, L Komuves, T Quertermous, ... Journal of Biological Chemistry 280 (26), 24680-24689, 2005 | 171 | 2005 |
