| Interleukin-13 is the key effector Th2 cytokine in ulcerative colitis that affects epithelial tight junctions, apoptosis, and cell restitution F Heller, P Florian, C Bojarski, J Richter, M Christ, B Hillenbrand, ... Gastroenterology 129 (2), 550-564, 2005 | 1516 | 2005 |
| Complex phenotype of mice lacking occludin, a component of tight junction strands M Saitou, M Furuse, H Sasaki, JD Schulzke, M Fromm, H Takano, T Noda, ... Molecular biology of the cell 11 (12), 4131-4142, 2000 | 1498 | 2000 |
| Changes in expression and distribution of claudin 2, 5 and 8 lead to discontinuous tight junctions and barrier dysfunction in active Crohn’s disease S Zeissig, N Bürgel, D Günzel, J Richter, J Mankertz, U Wahnschaffe, ... Gut 56 (1), 61-72, 2007 | 1449 | 2007 |
| Claudin-2 expression induces cation-selective channels in tight junctions of epithelial cells S Amasheh, N Meiri, AH Gitter, T Schöneberg, J Mankertz, JD Schulzke, ... Journal of cell science 115 (24), 4969-4976, 2002 | 996 | 2002 |
| Altered tight junction structure contributes to the impaired epithelial barrier function in ulcerative colitis H Schmitz, C Barmeyer, ML Fromm, N Runkel, HD Foss, CJ Bentzel, ... Gastroenterology 116 (2), 301-309, 1999 | 735 | 1999 |
| E‐cadherin is essential for in vivo epidermal barrier function by regulating tight junctions JA Tunggal, I Helfrich, A Schmitz, H Schwarz, D Günzel, M Fromm, ... The EMBO journal 24 (6), 1146-1156, 2005 | 563 | 2005 |
| Claudin-2, a component of the tight junction, forms a paracellular water channel R Rosenthal, S Milatz, SM Krug, B Oelrich, JD Schulzke, S Amasheh, ... Journal of cell science 123 (11), 1913-1921, 2010 | 520 | 2010 |
| Tumor necrosis factor-alpha (TNFα) regulates the epithelial barrier in the human intestinal cell line HT-29/B6 H Schmitz, M Fromm, CJ Bentzel, P Scholz, K Detjen, J Mankertz, H Bode, ... Journal of cell science 112 (1), 137-146, 1999 | 507 | 1999 |
| Epithelial tight junctions in intestinal inflammation JD Schulzke, S Ploeger, M Amasheh, A Fromm, S Zeissig, H Troeger, ... Annals of the New York Academy of Sciences 1165 (1), 294-300, 2009 | 476 | 2009 |
| Claudins and other tight junction proteins D Günzel, M Fromm Comprehensive Physiology 2 (3), 1819-1852, 2012 | 433 | 2012 |
| Crypts are the site of intestinal fluid and electrolyte secretion MJ Welsh, PL Smith, M Fromm, RA Frizzell Science 218 (4578), 1219-1221, 1982 | 428 | 1982 |
| Epithelial transport and barrier function in occludin-deficient mice JD Schulzke, AH Gitter, J Mankertz, S Spiegel, U Seidler, S Amasheh, ... Biochimica et biophysica acta (BBA)-Biomembranes 1669 (1), 34-42, 2005 | 417 | 2005 |
| Tricellulin forms a barrier to macromolecules in tricellular tight junctions without affecting ion permeability SM Krug, S Amasheh, JF Richter, S Milatz, D Günzel, JK Westphal, ... Molecular biology of the cell 20 (16), 3713-3724, 2009 | 401 | 2009 |
| Expression from the human occludin promoter is affected by tumor necrosis factor α and interferon γ J Mankertz, S Tavalali, H Schmitz, A Mankertz, EO Riecken, M Fromm, ... Journal of cell science 113 (11), 2085-2090, 2000 | 394 | 2000 |
| Downregulation of epithelial apoptosis and barrier repair in active Crohn’s disease by tumour necrosis factor α antibody treatment S Zeissig, C Bojarski, N Buergel, J Mankertz, M Zeitz, M Fromm, ... Gut 53 (9), 1295-1302, 2004 | 382 | 2004 |
| Effect of chronic Giardia lamblia infection on epithelial transport and barrier function in human duodenum H Troeger, HJ Epple, T Schneider, U Wahnschaffe, R Ullrich, ... Gut 56 (3), 328-335, 2007 | 366 | 2007 |
| Tight junction, selective permeability, and related diseases SM Krug, JD Schulzke, M Fromm Seminars in cell & developmental biology 36, 166-176, 2014 | 355 | 2014 |
| Molecular basis for cation selectivity in claudin-2–based paracellular pores: identification of an electrostatic interaction site ASL Yu, MH Cheng, S Angelow, D Günzel, SA Kanzawa, ... The Journal of general physiology 133 (1), 111-127, 2009 | 347 | 2009 |
| Leaks in the epithelial barrier caused by spontaneous and TNF‐α‐induced single‐cell apoptosis AH Gitter, K Bendfeldt, JD Schulzke, M Fromm The FASEB journal 14 (12), 1749-1753, 2000 | 342 | 2000 |
| Mechanisms of diarrhea in collagenous colitis N Bürgel, C Bojarski, J Mankertz, M Zeitz, M Fromm, JD Schulzke Gastroenterology 123 (2), 433-443, 2002 | 333 | 2002 |
