| Computational methods and tools in antimicrobial peptide research PGA Aronica, LM Reid, N Desai, J Li, SJ Fox, S Yadahalli, JW Essex, ... Journal of Chemical Information and Modeling 61 (7), 3172-3196, 2021 | 98 | 2021 |
| Macrocyclic α helical peptide therapeutic modality: A perspective of learnings and challenges TK Sawyer, AW Partridge, HYK Kaan, YC Juang, S Lim, C Johannes, ... Bioorganic & Medicinal Chemistry 26 (10), 2807-2815, 2018 | 62 | 2018 |
| Incorporation of putative helix-breaking amino acids in the design of novel stapled peptides: Exploring biophysical and cellular permeability properties AW Partridge, HYK Kaan, YC Juang, A Sadruddin, S Lim, CJ Brown, S Ng, ... Molecules 24 (12), 2292, 2019 | 56 | 2019 |
| Macrocyclization of an all-d linear α-helical peptide imparts cellular permeability S Kannan, PGA Aronica, S Ng, DTG Lian, Y Frosi, S Chee, J Shimin, ... Chemical Science 11 (21), 5577-5591, 2020 | 42 | 2020 |
| De-risking drug discovery of intracellular targeting peptides: screening strategies to eliminate false-positive hits S Ng, YC Juang, A Chandramohan, HYK Kaan, A Sadruddin, TY Yuen, ... ACS Medicinal Chemistry Letters 11 (10), 1993-2001, 2020 | 29 | 2020 |
| Design-rules for stapled peptides with in vivo activity and their application to Mdm2/X antagonists A Chandramohan, H Josien, TY Yuen, R Duggal, D Spiegelberg, L Yan, ... Nature communications 15 (1), 489, 2024 | 19 | 2024 |
| Inhibiting S100B (ββ) for activating wild-type p53: design of stapled peptides S Kannan, PGA Aronica, YS Tan, CS Verma ACS Omega 4 (3), 5335-5344, 2019 | 9 | 2019 |
| Comparison of charge derivation methods applied to amino acid parameterization PGA Aronica, SJ Fox, CS Verma ACS omega 3 (4), 4664-4673, 2018 | 9 | 2018 |
| Mutational Locally Enhanced Sampling (MULES) for quantitative prediction of the effects of mutations at protein–protein interfaces RT Bradshaw, PGA Aronica, EW Tate, RJ Leatherbarrow, IR Gould Chemical Science 3 (5), 1503-1511, 2012 | 7 | 2012 |
| Computational design of macrocyclic binders of S100B (ββ): novel peptide theranostics S Kannan, PGA Aronica, TB Nguyen, J Li, CS Verma Molecules 26 (3), 721, 2021 | 5 | 2021 |
| The Parasol Protocol for computational mutagenesis PGA Aronica, C Verma, B Popovic, RJ Leatherbarrow, IR Gould Protein Engineering, Design and Selection 29 (7), 253-261, 2016 | 4 | 2016 |
| Molecular descriptors suggest stapling as a strategy for optimizing membrane permeability of cyclic peptides J Li, S Kannan, P Aronica, CJ Brown, AW Partridge, CS Verma The Journal of Chemical Physics 156 (6), 2022 | 3 | 2022 |
| DStabilize: a web resource to generate mirror images of biomolecules AJ Malik, PGA Aronica, CS Verma Structure 28 (12), 1358-1360. e2, 2020 | 2 | 2020 |
| Design-Rules for Stapled Alpha-Helical Peptides with On-Target In Vivo Activity: Application to Mdm2/X dual antagonists A Chandramohan, H Josien, TY Yuen, R Duggal, D Spiegelberg, L Yan, ... Biorxiv, 2023.02. 25.530030, 2023 | 1 | 2023 |
| Author Correction: Design-rules for stapled peptides with in vivo activity and their application to Mdm2/X antagonists A Chandramohan, H Josien, TY Yuen, R Duggal, D Spiegelberg, L Yan, ... Nature Communications 16 (1), 1617, 2025 | | 2025 |
| Macrocyclic peptides as potent inhibitors of k-ras g12d mutant NC Boyer, MB Garrigou, SN Ha, C Huang, AW Partridge, TK Sawyer, ... US Patent App. 17/783,224, 2023 | | 2023 |
| P53 activator peptidomimetic macrocycles P Aronica, CJ Brown, FJ Ferrer, CW Johannes, S Kannan, DP Lane, ... US Patent App. 17/618,751, 2022 | | 2022 |
| Macrocyclization of an all-D linear peptide improves target affinity and imparts cellular activity: A novel stapled α-helical peptide modality S Kannan, PGA Aronica, S Ng, D Thean, Y Frosi, S Chee, J Shimin, ... bioRxiv, 767673, 2019 | | 2019 |
| Development of a New Protocol for Computatinal Site-directed Mutagenesis P Aronica, IR Gould, RJ Leatherbarrow Imperial College London, 2016 | | 2016 |
| Developing mutational locally enhanced sampling (MULES) for predicting relative binding free energies at protein-protein interfaces RT Bradshaw, PGA Aronica, EW Tate, RJ Leatherbarrow, IR Gould ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 243, 2012 | | 2012 |
