Paradoxical false memory for objects after brain damage SM McTighe, RA Cowell, BD Winters, TJ Bussey, LM Saksida Science 330 (6009), 1408-1410, 2010 | 170 | 2010 |
CLK2 inhibition ameliorates autistic features associated with SHANK3 deficiency M Bidinosti, P Botta, S Krüttner, CC Proenca, N Stoehr, M Bernhard, I Fruh, ... Science 351 (6278), 1199-1203, 2016 | 156 | 2016 |
The BTBR mouse model of autism spectrum disorders has learning and attentional impairments and alterations in acetylcholine and kynurenic acid in prefrontal cortex SM McTighe, SJ Neal, Q Lin, ZA Hughes, DG Smith PloS one 8 (4), e62189, 2013 | 139 | 2013 |
Trial-unique, delayed nonmatching-to-location (TUNL): a novel, highly hippocampus-dependent automated touchscreen test of location memory and pattern separation JC Talpos, SM McTighe, R Dias, LM Saksida, TJ Bussey Neurobiology of learning and memory 94 (3), 341-352, 2010 | 133 | 2010 |
A new touchscreen test of pattern separation: effect of hippocampal lesions SM McTighe, AC Mar, C Romberg, TJ Bussey, LM Saksida Neuroreport 20 (9), 881-885, 2009 | 128 | 2009 |
False recognition in a mouse model of Alzheimer’s disease: rescue with sensory restriction and memantine C Romberg, SM McTighe, CJ Heath, DJ Whitcomb, K Cho, TJ Bussey, ... Brain 135 (7), 2103-2114, 2012 | 63 | 2012 |
Emerging gene and small molecule therapies for the neurodevelopmental disorder angelman syndrome NA Copping, SM McTighe, KD Fink, JL Silverman Neurotherapeutics 18 (3), 1535-1547, 2021 | 26 | 2021 |
Discovery of a brain-penetrant ATP-competitive inhibitor of the mechanistic target of rapamycin (mTOR) for CNS disorders S Bonazzi, CP Goold, A Gray, NM Thomsen, J Nunez, RG Karki, A Gorde, ... Journal of Medicinal Chemistry 63 (3), 1068-1083, 2020 | 26 | 2020 |
FK962 and donepezil act synergistically to improve cognition in rats: potential as an add-on therapy for Alzheimer's disease AD McCarthy, IJ Owens, AT Bansal, SM McTighe, TJ Bussey, LM Saksida Pharmacology Biochemistry and Behavior 98 (1), 76-80, 2011 | 21 | 2011 |
Genetic background and sex: impact on generalizability of research findings in pharmacology studies SJ Sukoff Rizzo, S McTighe, DL McKinzie Good Research Practice in Non-Clinical Pharmacology and Biomedicine, 147-162, 2020 | 17 | 2020 |
Translational neuroimaging: tools for CNS drug discovery, development and treatment RA McArthur Academic Press, 2012 | 10 | 2012 |
A new touchscreen test of pattern separation: Effect of hippocampal lesions. NeuroReport: For Rapid Communication of Neuroscience Research, 20 (9), 881–885 SM McTighe, AC Mar, C Romberg, TJ Bussey, LM Saksida | 10 | 2009 |
Discovery and characterization of novel TRPML1 agonists X Peng, CJ Holler, AMF Alves, MG Oliviera, M Speake, A Pugliese, ... Bioorganic & Medicinal Chemistry Letters 98, 129595, 2024 | 2 | 2024 |
Seizure reduction in TSC2‐mutant mouse model by an mTOR catalytic inhibitor SC Dhamne, ME Modi, A Gray, S Bonazzi, L Craig, E Bainbridge, L Lalani, ... Annals of clinical and translational neurology 10 (10), 1790-1801, 2023 | 2 | 2023 |
Translational neuroimaging for drug discovery and development in autism spectrum disorders: guidance from clinical imaging and preclinical research LL Badura, MD Saxe, C Risterucci, MJ Brammer, SM McTighe, RH Ring, ... Translational Neuroimaging, 245-280, 2013 | 2 | 2013 |
ARKD‐104, A Potential Treatment of Frontotemporal Dementia and Other Neurodegenerative Disorders SW Hung, RS Hurst, JF Blain, CJ Holler, AYP Chen, MA Brand, AM Alves, ... Alzheimer's & Dementia 19, e074362, 2023 | | 2023 |
Identification of Brain-Penetrant ATP-Competitive mTOR Inhibitors for CNS Syndromes S Bonazzi, A Gray, NM Thomsen, J Biag, N Labbe-Giguere, EP Keaney, ... Journal of Medicinal Chemistry 66 (13), 9095-9119, 2023 | | 2023 |
Translational Neuroimaging for Drug Discovery and Development in Autism Spectrum Disorders LL Badura, MD Saxe, C Risterucci, MJ Brammer, SM McTighe, RH Ring, ... Tools for CNS Drug Discovery, Development and Treatment, 245, 2012 | | 2012 |
Mechanisms of memory and pattern separation in rodent models of amnesia and dementia SM McTighe University of Cambridge, 2012 | | 2012 |