| Distinct cysteine residues in Keap1 are required for Keap1-dependent ubiquitination of Nrf2 and for stabilization of Nrf2 by chemopreventive agents and oxidative stress DD Zhang, M Hannink Molecular and cellular biology, 2003 | 1676 | 2003 |
| Nrf2 is a direct PERK substrate and effector of PERK-dependent cell survival SB Cullinan, D Zhang, M Hannink, E Arvisais, RJ Kaufman, JA Diehl Molecular and cellular biology 23 (20), 7198-7209, 2003 | 1454 | 2003 |
| Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex DD Zhang, SC Lo, JV Cross, DJ Templeton, M Hannink Molecular and cellular biology, 2004 | 1452 | 2004 |
| Phosphorylation-dependent regulation of cyclin D1 nuclear export and cyclin D1–dependent cellular transformation JR Alt, JL Cleveland, M Hannink, JA Diehl Genes & development 14 (24), 3102-3114, 2000 | 693 | 2000 |
| Structure of the Keap1: Nrf2 interface provides mechanistic insight into Nrf2 signaling SC Lo, X Li, MT Henzl, LJ Beamer, M Hannink The EMBO journal 25 (15), 3605-3617, 2006 | 562 | 2006 |
| Ubiquitination of Keap1, a BTB-Kelch substrate adaptor protein for Cul3, targets Keap1 for degradation by a proteasome-independent pathway DD Zhang, SC Lo, Z Sun, GM Habib, MW Lieberman, M Hannink Journal of Biological Chemistry 280 (34), 30091-30099, 2005 | 359 | 2005 |
| The v-rel oncogene encodes a κB enhancer binding protein that inhibits NF-κB function DW Ballard, WH Walker, S Doerre, P Sista, JA Molitor, EP Dixon, ... Cell 63 (4), 803-814, 1990 | 356 | 1990 |
| PGAM5 tethers a ternary complex containing Keap1 and Nrf2 to mitochondria SC Lo, M Hannink Experimental cell research 314 (8), 1789-1803, 2008 | 345 | 2008 |
| Docosahexaenoic acid (DHA): An essential nutrient and a nutraceutical for brain health and diseases GY Sun, A Simonyi, KL Fritsche, DY Chuang, M Hannink, Z Gu, ... Prostaglandins, Leukotrienes and Essential Fatty Acids 136, 3-13, 2018 | 309 | 2018 |
| Crystal structure of the Kelch domain of human Keap1 X Li, D Zhang, M Hannink, LJ Beamer Journal of Biological Chemistry 279 (52), 54750-54758, 2004 | 291 | 2004 |
| PGAM5, a Bcl-XL-interacting protein, is a novel substrate for the redox-regulated Keap1-dependent ubiquitin ligase complex SC Lo, M Hannink Journal of Biological Chemistry 281 (49), 37893-37903, 2006 | 231 | 2006 |
| Embryotoxicity of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD): Theembryonic vasculature is a physiological target for TCDD-induced DNA damage and apoptotic cell death in … SM Cantrell, LH Lutz, DE Tillitt, M Hannink Toxicology and applied pharmacology 141 (1), 23-34, 1996 | 209 | 1996 |
| Nuclear Localization of IκBα Is Mediated by the Second Ankyrin Repeat: the IκBα Ankyrin Repeats Define a Novel Class of cis-Acting Nuclear Import Sequences S Sachdev, A Hoffmann, M Hannink Molecular and cellular biology 18 (5), 2524-2534, 1998 | 208* | 1998 |
| Cul3-mediated Nrf2 ubiquitination and antioxidant response element (ARE) activation are dependent on the partial molar volume at position 151 of Keap1 AL Eggler, E Small, M Hannink, AD Mesecar Biochemical journal 422 (1), 171-180, 2009 | 200 | 2009 |
| Quercetin attenuates inflammatory responses in BV-2 microglial cells: role of MAPKs on the Nrf2 pathway and induction of heme oxygenase-1 GY Sun, Z Chen, KJ Jasmer, DY Chuang, Z Gu, M Hannink, A Simonyi PloS one 10 (10), e0141509, 2015 | 182 | 2015 |
| Correlation of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin-induced apoptotic cell death in the embryonic vasculature with embryotoxicity SM Cantrell, J Joy-Schlezinger, JJ Stegeman, DE Tillitt, M Hannink Toxicology and applied pharmacology 148 (1), 24-34, 1998 | 179 | 1998 |
| Modulation of Phototropic Responsiveness in Arabidopsis through Ubiquitination of Phototropin 1 by the CUL3-Ring E3 Ubiquitin Ligase CRL3NPH3 D Roberts, UV Pedmale, J Morrow, S Sachdev, E Lechner, X Tang, ... The Plant Cell 23 (10), 3627-3640, 2011 | 165 | 2011 |
| Structure and function of platelet-derived growth factor (PDGF) and related proteins M Hannink, DJ Donoghue Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 989 (1), 1-10, 1989 | 162 | 1989 |
| Identification of oxygen-sensitive transcriptional programs in human embryonic stem cells SD Westfall, S Sachdev, P Das, LB Hearne, M Hannink, RM Roberts, ... Stem cells and development 17 (5), 869-882, 2008 | 158 | 2008 |
| Effects of interventions on oxidative stress and inflammation of cardiovascular diseases S Lee, Y Park, MY Zuidema, M Hannink, C Zhang World Journal of Cardiology 3 (1), 18, 2011 | 154 | 2011 |
