| Voltage-gated ion channels in cancer cell proliferation VR Rao, M Perez-Neut, S Kaja, S Gentile Cancers 7 (2), 849-875, 2015 | 230 | 2015 |
| Rapid signaling at the plasma membrane by a nuclear receptor for thyroid hormone NM Storey, S Gentile, H Ullah, A Russo, M Muessel, C Erxleben, ... Proceedings of the National Academy of Sciences 103 (13), 5197-5201, 2006 | 142 | 2006 |
| Cyclosporin and Timothy syndrome increase mode 2 gating of CaV1. 2 calcium channels through aberrant phosphorylation of S6 helices C Erxleben, Y Liao, S Gentile, D Chin, C Gomez-Alegria, Y Mori, ... Proceedings of the National Academy of Sciences 103 (10), 3932-3937, 2006 | 133 | 2006 |
| A rapid cytoplasmic mechanism for PI3 kinase regulation by the nuclear thyroid hormone receptor, TRß, and genetic evidence for its role in the maturation of mouse hippocampal … DLA Negin P. Martin, Ezequiel Marron Fernandez de Velasco, Fengxia Mizuno ... Endocrinology, 2013-2058, 2014 | 90* | 2014 |
| Caveolin-1 controls mitochondrial damage and ROS production by regulating fission-fusion dynamics and mitophagy Y Jiang, S Krantz, X Qin, S Li, H Gunasekara, YM Kim, A Zimnicka, M Bae, ... Redox biology 52, 102304, 2022 | 87 | 2022 |
| Potassium channel activity controls breast cancer metastasis by affecting β-catenin signaling EK Breuer, D Fukushiro-Lopes, A Dalheim, M Burnette, J Zartman, S Kaja, ... Cell death & disease 10 (3), 180, 2019 | 82 | 2019 |
| Potassium channel activation inhibits proliferation of breast cancer cells by activating a senescence program K Lansu, S Gentile Cell death & disease 4 (6), e652-e652, 2013 | 82 | 2013 |
| Rac GTPase signaling through the PP5 protein phosphatase S Gentile, T Darden, C Erxleben, C Romeo, A Russo, N Martin, S Rossie, ... Proceedings of the National Academy of Sciences 103 (13), 5202-5206, 2006 | 56 | 2006 |
| Preclinical study of a Kv11. 1 potassium channel activator as antineoplastic approach for breast cancer DF Fukushiro-Lopes, AD Hegel, V Rao, D Wyatt, A Baker, EK Breuer, ... Oncotarget 9 (3), 3321, 2017 | 53 | 2017 |
| The human ERG1 channel polymorphism, K897T, creates a phosphorylation site that inhibits channel activity S Gentile, N Martin, E Scappini, J Williams, C Erxleben, DL Armstrong Proceedings of the National Academy of Sciences 105 (38), 14704-14708, 2008 | 53 | 2008 |
| Multiomic analysis identifies CPT1A as a potential therapeutic target in platinum-refractory, high-grade serous ovarian cancer D Huang, S Chowdhury, H Wang, SR Savage, RG Ivey, JJ Kennedy, ... Cell Reports Medicine 2 (12), 2021 | 44 | 2021 |
| Activation of hERG3 channel stimulates autophagy and promotes cellular senescence in melanoma M Perez-Neut, L Haar, V Rao, S Santha, K Lansu, B Rana, WK Jones, ... Oncotarget 7 (16), 21991, 2016 | 40 | 2016 |
| (+)-Strebloside-induced cytotoxicity in ovarian cancer cells is mediated through cardiac glycoside signaling networks WL Chen, Y Ren, J Ren, C Erxleben, ME Johnson, S Gentile, ... Journal of natural products 80 (3), 659-669, 2017 | 37 | 2017 |
| Stimulation of hERG1 channel activity promotes a calcium-dependent degradation of cyclin E2, but not cyclin E1, in breast cancer cells M Perez-Neut, A Shum, BD Cuevas, R Miller, S Gentile Oncotarget 6 (3), 1631, 2015 | 36 | 2015 |
| hERG1/Kv11. 1 activation stimulates transcription of p21waf/cip in breast cancer cells via a calcineurin-dependent mechanism M Perez-Neut, VR Rao, S Gentile Oncotarget 7 (37), 58893, 2015 | 35 | 2015 |
| Repurposing Kir6/SUR2 channel activator minoxidil to arrests growth of gynecologic cancers D Fukushiro-Lopes, AD Hegel, A Russo, V Senyuk, M Liotta, GC Beeson, ... Frontiers in Pharmacology 11, 577, 2020 | 23 | 2020 |
| hERG1 potassium channel in cancer cells: a tool to reprogram immortality S Gentile European Biophysics Journal 45, 649-655, 2016 | 20 | 2016 |
| Compensatory expression of NRF2-dependent antioxidant genes is required to overcome the lethal effects of Kv11. 1 activation in breast cancer cells and PDOs V Senyuk, N Eskandari, Y Jiang, R Garcia-Varela, R Sundstrom, L Leanza, ... Redox biology 45, 102030, 2021 | 16 | 2021 |
| MEKK2 regulates paxillin ubiquitylation and localization in MDA-MB 231 breast cancer cells M Ameka, MP Kahle, M Perez-Neut, S Gentile, AA Mirza, BD Cuevas Biochemical Journal 464 (1), 99-108, 2014 | 15 | 2014 |
| Molecular activation of the Kv11. 1 channel reprograms EMT in colon cancer by inhibiting TGFβ signaling via activation of calcineurin N Eskandari, V Senyuk, J Moore, Z Kalik, Q Luan, I Papautsky, A Moshiri, ... Cancers 13 (23), 6025, 2021 | 14 | 2021 |