| Gut microbiota and intestinal FXR mediate the clinical benefits of metformin L Sun, C Xie, G Wang, Y Wu, Q Wu, X Wang, J Liu, Y Deng, J Xia, B Chen, ... Nature medicine 24 (12), 1919-1929, 2018 | 846 | 2018 |
| Intestinal farnesoid X receptor signaling promotes nonalcoholic fatty liver disease C Jiang, C Xie, F Li, L Zhang, RG Nichols, KW Krausz, J Cai, Y Qi, ... The Journal of clinical investigation 125 (1), 386-402, 2015 | 703 | 2015 |
| Ketogenic diets alter the gut microbiome resulting in decreased intestinal Th17 cells QY Ang, M Alexander, JC Newman, Y Tian, J Cai, V Upadhyay, ... Cell 181 (6), 1263-1275. e16, 2020 | 427 | 2020 |
| Microbiota fermentation-NLRP3 axis shapes the impact of dietary fibres on intestinal inflammation V Singh, B San Yeoh, RE Walker, X Xiao, P Saha, RM Golonka, J Cai, ... Gut 68 (10), 1801-1812, 2019 | 196 | 2019 |
| Bile acid metabolism and signaling, the microbiota, and metabolic disease J Cai, B Rimal, C Jiang, JYL Chiang, AD Patterson Pharmacology & Therapeutics 237, 108238, 2022 | 175 | 2022 |
| The microbiome modulating activity of bile acids Y Tian, W Gui, I Koo, PB Smith, EL Allman, RG Nichols, B Rimal, J Cai, ... Gut microbes 11 (4), 979-996, 2020 | 173 | 2020 |
| Caloric restriction disrupts the microbiota and colonization resistance RJ von Schwartzenberg, JE Bisanz, S Lyalina, P Spanogiannopoulos, ... Nature 595 (7866), 272-277, 2021 | 170 | 2021 |
| Microbiota-dependent hepatic lipogenesis mediated by stearoyl CoA desaturase 1 (SCD1) promotes metabolic syndrome in TLR5-deficient mice V Singh, B Chassaing, L Zhang, B San Yeoh, X Xiao, M Kumar, MT Baker, ... Cell metabolism 22 (6), 983-996, 2015 | 167 | 2015 |
| Spleen injury and apoptotic pathway in mice caused by titanium dioxide nanoparticules N Li, Y Duan, M Hong, L Zheng, M Fei, X Zhao, J Wang, Y Cui, H Liu, ... Toxicology letters 195 (2-3), 161-168, 2010 | 135 | 2010 |
| P38-Nrf-2 Signaling Pathway of Oxidative Stress in Mice Caused by Nanoparticulate TiO2 J Wang, N Li, L Zheng, S Wang, Y Wang, X Zhao, Y Duan, Y Cui, M Zhou, ... Biological Trace Element Research 140, 186-197, 2011 | 116 | 2011 |
| Farnesoid X receptor signaling shapes the gut microbiota and controls hepatic lipid metabolism L Zhang, C Xie, RG Nichols, SHJ Chan, C Jiang, R Hao, PB Smith, J Cai, ... MSystems 1 (5), 10.1128/msystems. 00070-16, 2016 | 103 | 2016 |
| Bacterial colonization reprograms the neonatal gut metabolome K Bittinger, C Zhao, Y Li, E Ford, ES Friedman, J Ni, CV Kulkarni, J Cai, ... Nature microbiology 5 (6), 838-847, 2020 | 98 | 2020 |
| Berberine directly affects the gut microbiota to promote intestinal farnesoid X receptor activation Y Tian, J Cai, W Gui, RG Nichols, I Koo, J Zhang, M Anitha, AD Patterson Drug Metabolism and Disposition 47 (2), 86-93, 2019 | 95 | 2019 |
| Oxidative damages of maize seedlings caused by exposure to a combination of potassium deficiency and salt stress X Gong, L Chao, M Zhou, M Hong, L Luo, L Wang, W Ying, C Jingwei, ... Plant and soil 340, 443-452, 2011 | 91 | 2011 |
| Immune dysfunction and liver damage of mice following exposure to lanthanoids J Cheng, Z Cheng, R Hu, Y Cui, J Cai, N Li, S Gui, X Sang, Q Sun, ... Environmental Toxicology 29 (1), 64-73, 2014 | 77 | 2014 |
| Orthogonal Comparison of GC–MS and 1H NMR Spectroscopy for Short Chain Fatty Acid Quantitation J Cai, J Zhang, Y Tian, L Zhang, E Hatzakis, KW Krausz, PB Smith, ... Analytical chemistry 89 (15), 7900-7906, 2017 | 70 | 2017 |
| Vitamin A deficiency in mice alters host and gut microbial metabolism leading to altered energy homeostasis Y Tian, RG Nichols, J Cai, AD Patterson, MT Cantorna The Journal of nutritional biochemistry 54, 28-34, 2018 | 67 | 2018 |
| Ursodeoxycholic acid (UDCA) mitigates the host inflammatory response during Clostridioides difficile infection by altering gut bile acids JA Winston, AJ Rivera, J Cai, R Thanissery, SA Montgomery, ... Infection and Immunity 88 (6), 10.1128/iai. 00045-20, 2020 | 59 | 2020 |
| Attenuation of Microbiotal Dysbiosis and Hypertension in a CRISPR/Cas9 Gene Ablation Rat Model of GPER1 H Waghulde, X Cheng, S Galla, B Mell, J Cai, SM Pruett-Miller, ... Hypertension 72 (5), 1125-1132, 2018 | 58 | 2018 |
| Gdf15 regulates murine stress erythroid progenitor proliferation and the development of the stress erythropoiesis niche S Hao, J Xiang, DC Wu, JW Fraser, B Ruan, J Cai, AD Patterson, ZC Lai, ... Blood advances 3 (14), 2205-2217, 2019 | 45 | 2019 |
Andrew D. PattersonProfessor of Molecular Toxicology, Penn State UniversityVerified email at psu.edu